Glucocorticosteroids as Dengue Therapeutics: Resolving Clinical Observations With a Primary Human Macrophage Model

por Sayce, Andrew C., Miller, Joanna L., Zitzmann, Nicole
Publicado 2013

Mechanisms of Antiviral Activity of Iminosugars Against Dengue Virus

por Miller, Joanna L., Tyrrell, Beatrice E., Zitzmann, Nicole
Publicado 2018

Iminosugar antivirals: the therapeutic sweet spot

por Alonzi, Dominic S., Scott, Kathryn A., Dwek, Raymond A., Zitzmann, Nicole
Publicado 2017

Absolute quantitation of disease protein biomarkers in a single LC-MS acquisition using apolipoprotein F as an example

por Kumar, Abhinav, Gangadharan, Bevin, Cobbold, Jeremy, Thursz, Mark, Zitzmann, Nicole
Publicado 2017

Host-targeting oral antiviral drugs to prevent pandemics

por Dwek, Raymond A, Bell, John I, Feldmann, Marc, Zitzmann, Nicole
Publicado 2022

Role of disulfide bond formation in the folding and assembly of the envelope glycoproteins of a pestivirus

por Branza-Nichita, Norica, Lazar, Catalin, Durantel, David, Dwek, Raymond A, Zitzmann, Nicole
Publicado 2002

In Planta Preliminary Screening of ER Glycoprotein Folding Quality Control (ERQC) Modulators

por Marti, Lucia, Lia, Andrea, Reca, Ida-Barbara, Roversi, Pietro, Santino, Angelo, Zitzmann, Nicole
Publicado 2018

Iminosugars: Promising therapeutics for influenza infection

por Tyrrell, Beatrice Ellen, Sayce, Andrew Cameron, Warfield, Kelly Lyn, Miller, Joanna Louise, Zitzmann, Nicole
Publicado 2017

Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells

por Perera, Nilanka, Brun, Juliane, Alonzi, Dominic S., Tyrrell, Beatrice E., Miller, Joanna L., Zitzmann, Nicole
Publicado 2022

Iminosugars counteract the downregulation of the interferon γ receptor by dengue virus

por Miller, Joanna L., Hill, Michelle L., Brun, Juliane, Pountain, Andrew, Sayce, Andrew C., Zitzmann, Nicole
Publicado 2019

Molecular basis of MHC I quality control in the peptide loading complex

por Domnick, Alexander, Winter, Christian, Sušac, Lukas, Hennecke, Leon, Hensen, Mario, Zitzmann, Nicole, Trowitzsch, Simon, Thomas, Christoph, Tampé, Robert
Publicado 2022

New Approaches for Biomarker Discovery: The Search for Liver Fibrosis Markers in Hepatitis C Patients

por Gangadharan, Bevin, Antrobus, Robin, Chittenden, David, Rossa, Jan, Bapat, Manisha, Klenerman, Paul, Barnes, Eleanor, Dwek, Raymond A., Zitzmann, Nicole
Publicado 2011

Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review

por Bharucha, Tehmina, Gangadharan, Bevin, Kumar, Abhinav, de Lamballerie, Xavier, Newton, Paul N., Winterberg, Markus, Dubot-Pérès, Audrey, Zitzmann, Nicole
Publicado 2019

Discovery of Novel Biomarker Candidates for Liver Fibrosis in Hepatitis C Patients: A Preliminary Study

por Gangadharan, Bevin, Bapat, Manisha, Rossa, Jan, Antrobus, Robin, Chittenden, David, Kampa, Bettina, Barnes, Eleanor, Klenerman, Paul, Dwek, Raymond A., Zitzmann, Nicole
Publicado 2012

Transcriptome Sequencing, Microarray, and Proteomic Analyses Reveal Cellular and Metabolic Impact of Hepatitis C Virus Infection In Vitro

por Woodhouse, Stephen D, Narayan, Ramamurthy, Latham, Sally, Lee, Sheena, Antrobus, Robin, Gangadharan, Bevin, Luo, Shujun, Schroth, Gary P, Klenerman, Paul, Zitzmann, Nicole
Publicado 2010

ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity

por Kiappes, J. L., Hill, Michelle L., Alonzi, Dominic S., Miller, Joanna L., Iwaki, Ren, Sayce, Andrew C., Caputo, Alessandro T., Kato, Atsushi, Zitzmann, Nicole
Publicado 2017

Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features

por Oestringer, Benjamin P., Bolivar, Juan H., Claridge, Jolyon K., Almanea, Latifah, Chipot, Chris, Dehez, François, Holzmann, Nicole, Schnell, Jason R., Zitzmann, Nicole
Publicado 2019

A need to raise the bar — A systematic review of temporal trends in diagnostics for Japanese encephalitis virus infection, and perspectives for future research

por Bharucha, Tehmina, Shearer, Freya M., Vongsouvath, Manivanh, Mayxay, Mayfong, de Lamballerie, Xavier, Newton, Paul N., Zitzmann, Nicole, Gould, Ernest, Dubot-Pérès, Audrey
Publicado 2020

Pathogen‐induced inflammation is attenuated by the iminosugar MON‐DNJ via modulation of the unfolded protein response

por Sayce, Andrew C., Martinez, Fernando O., Tyrrell, Beatrice E., Perera, Nilanka, Hill, Michelle L., Dwek, Raymond A., Miller, Joanna L., Zitzmann, Nicole
Publicado 2021

Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint

por Caputo, Alessandro T., Ibba, Roberta, Le Cornu, James D., Darlot, Benoit, Hensen, Mario, Lipp, Colette B., Marcianò, Gabriele, Vasiljević, Snežana, Zitzmann, Nicole, Roversi, Pietro
Publicado 2022