Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

por Rut, Wioletta, Zmudzinski, Mikolaj, Snipas, Scott J., Bekes, Miklos, Huang, Tony T., Drag, Marcin
Publicado 2020

Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors–Molecular Docking and In Vitro Study

por Nawrot-Hadzik, Izabela, Zmudzinski, Mikolaj, Matkowski, Adam, Preissner, Robert, Kęsik-Brodacka, Małgorzata, Hadzik, Jakub, Drag, Marcin, Abel, Renata
Publicado 2021

Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding

por Perlinska, Agata P., Stasiulewicz, Adam, Nguyen, Mai Lan, Swiderska, Karolina, Zmudzinski, Mikolaj, Maksymiuk, Alicja W., Drag, Marcin, Sulkowska, Joanna I.
Publicado 2022

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design

por Rut, Wioletta, Lv, Zongyang, Zmudzinski, Mikolaj, Patchett, Stephanie, Nayak, Digant, Snipas, Scott J., El Oualid, Farid, Huang, Tony T., Bekes, Miklos, Drag, Marcin, Olsen, Shaun K.
Publicado 2020

Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts

por Strub, Daniel Jan, Talma, Michał, Strub, Maria, Rut, Wioletta, Zmudzinski, Mikolaj, Brud, Władysław, Neyts, Johan, Vangeel, Laura, Zhang, Linlin, Sun, Xinyuanyuan, Lv, Zongyang, Nayak, Digant, Olsen, Shaun K., Hilgenfeld, Rolf, Jochmans, Dirk, Drąg, Marcin
Publicado 2022

Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PL(pro) and M(pro) proteases, and nsp14 guanine N7-methyltransferase

por Zmudzinski, Mikolaj, Rut, Wioletta, Olech, Kamila, Granda, Jarosław, Giurg, Mirosław, Burda-Grabowska, Małgorzata, Kaleta, Rafał, Zgarbova, Michala, Kasprzyk, Renata, Zhang, Linlin, Sun, Xinyuanyuan, Lv, Zongyang, Nayak, Digant, Kesik-Brodacka, Malgorzata, Olsen, Shaun K., Weber, Jan, Hilgenfeld, Rolf, Jemielity, Jacek, Drag, Marcin
Publicado 2023

SARS-CoV-2 M(pro) Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals

por Chen, Sizhu Amelia, Arutyunova, Elena, Lu, Jimmy, Khan, Muhammad Bashir, Rut, Wioletta, Zmudzinski, Mikolaj, Shahbaz, Shima, Iyyathurai, Jegan, Moussa, Eman W., Turner, Zoe, Bai, Bing, Lamer, Tess, Nieman, James A., Vederas, John C., Julien, Olivier, Drag, Marcin, Elahi, Shokrollah, Young, Howard S., Lemieux, M. Joanne
Publicado 2023