Discovery of the SHP2 allosteric inhibitor 2-((3R,4R)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-5-(2,3-dichlorophenyl)-3-methylpyrrolo[2,1-f][1,2,4] triazin-4(3H)-one

por Luo, Yanmei, Li, Jin, Zong, Yuliang, Sun, Mengxin, Zheng, Wan, Zhu, Jiapeng, Liu, Liu, Liu, Bing
Publicado 2022

Structures of the CcmABCD heme release complex at multiple states

por Li, Jiao, Zheng, Wan, Gu, Ming, Han, Long, Luo, Yanmei, Yu, Koukou, Sun, Mengxin, Zong, Yuliang, Ma, Xiuxiu, Liu, Bing, Lowder, Ethan P., Mendez, Deanna L., Kranz, Robert G., Zhang, Kai, Zhu, Jiapeng
Publicado 2022