PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity

por Fischer, Jan M. F., Zubel, Tabea, Jander, Kirsten, Fix, Jelena, Trussina, Irmela R. E. A., Gebhard, Daniel, Bergemann, Jörg, Bürkle, Alexander, Mangerich, Aswin
Publicado 2017

Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo

por Schuhwerk, Harald, Bruhn, Christopher, Siniuk, Kanstantsin, Min, Wookee, Erener, Suheda, Grigaravicius, Paulius, Krüger, Annika, Ferrari, Elena, Zubel, Tabea, Lazaro, David, Monajembashi, Shamci, Kiesow, Kirstin, Kroll, Torsten, Bürkle, Alexander, Mangerich, Aswin, Hottiger, Michael, Wang, Zhao-Qi
Publicado 2017

PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response

por Aberle, Lisa, Krüger, Annika, Reber, Julia M, Lippmann, Michelle, Hufnagel, Matthias, Schmalz, Michael, Trussina, Irmela R E A, Schlesiger, Sarah, Zubel, Tabea, Schütz, Karina, Marx, Andreas, Hartwig, Andrea, Ferrando-May, Elisa, Bürkle, Alexander, Mangerich, Aswin
Publicado 2020

Analyzing structure–function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells

por Rank, Lisa, Veith, Sebastian, Gwosch, Eva C., Demgenski, Janine, Ganz, Magdalena, Jongmans, Marjolijn C., Vogel, Christopher, Fischbach, Arthur, Buerger, Stefanie, Fischer, Jan M.F., Zubel, Tabea, Stier, Anna, Renner, Christina, Schmalz, Michael, Beneke, Sascha, Groettrup, Marcus, Kuiper, Roland P., Bürkle, Alexander, Ferrando-May, Elisa, Mangerich, Aswin
Publicado 2016