The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome

por Zuliani, Ilaria, Lanzillotta, Chiara, Tramutola, Antonella, Francioso, Antonio, Pagnotta, Sara, Barone, Eugenio, Perluigi, Marzia, Di Domenico, Fabio
Publicado 2020

BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain—Implications for Neurodegeneration

por Lanzillotta, Chiara, Zuliani, Ilaria, Vasavda, Chirag, Snyder, Solomon H., Paul, Bindu D., Perluigi, Marzia, Di Domenico, Fabio, Barone, Eugenio
Publicado 2020

Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome

por Tramutola, Antonella, Lanzillotta, Chiara, Barone, Eugenio, Arena, Andrea, Zuliani, Ilaria, Mosca, Luciana, Blarzino, Carla, Butterfield, D. Allan, Perluigi, Marzia, Di Domenico, Fabio
Publicado 2018

The Anti-Diabetic Drug Metformin Rescues Aberrant Mitochondrial Activity and Restrains Oxidative Stress in a Female Mouse Model of Rett Syndrome

por Zuliani, Ilaria, Urbinati, Chiara, Valenti, Daniela, Quattrini, Maria Cristina, Medici, Vanessa, Cosentino, Livia, Pietraforte, Donatella, Di Domenico, Fabio, Perluigi, Marzia, Vacca, Rosa Anna, De Filippis, Bianca
Publicado 2020

Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome

por Di Domenico, Fabio, Tramutola, Antonella, Barone, Eugenio, Lanzillotta, Chiara, Defever, Olivia, Arena, Andrea, Zuliani, Ilaria, Foppoli, Cesira, Iavarone, Federica, Vincenzoni, Federica, Castagnola, Massimo, Butterfield, D. Allan, Perluigi, Marzia
Publicado 2019

High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer’s Disease Signatures

por Zuliani, Ilaria, Lanzillotta, Chiara, Tramutola, Antonella, Barone, Eugenio, Perluigi, Marzia, Rinaldo, Serena, Paone, Alessio, Cutruzzolà, Francesca, Bellanti, Francesco, Spinelli, Matteo, Natale, Francesca, Fusco, Salvatore, Grassi, Claudio, Di Domenico, Fabio
Publicado 2021