A Highly Focused Antigen Receptor Repertoire Characterizes γδ T Cells That are Poised to Make IL-17 Rapidly in Naive Animals

por Wei, Yu-Ling, Han, Arnold, Glanville, Jacob, Fang, Fengqin, Zuniga, Luis Alejandro, Lee, Jacob S., Cua, Daniel J., Chien, Yueh-hsiu
Publicado 2015

Intratumoral delivery of TransCon(™) TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction

por Zúñiga, Luis Alejandro, Leßmann, Torben, Uppal, Karan, Bisek, Nicola, Hong, Enping, Rasmussen, Caroline E., Karlsson, Jens-Jakob, Zettler, Joachim, Holten-Andersen, Lars, Bang, Kathy, Thakar, Dhruv, Lee, Yu-Chi, Martinez, Salomon, Sabharwal, Simran Singh, Stark, Sebastian, Faltinger, Frank, Kracker, Oliver, Weisbrod, Samuel, Müller, Robin, Voigt, Tobias, Bigott, Kornelia, Tabrizifard, Mohammad, Breinholt, Vibeke Miller, Mirza, Amer M., Rosen, David B., Sprogøe, Kennett, Punnonen, Juha
Publicado 2022

TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune...

por Rosen, David B, Kvarnhammar, Anne Månsson, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Hong, Enping, Lee, Yu-Chi, Thakar, Dhruv, Zúñiga, Luis Alejandro, Bang, Kathy, Sabharwal, Simran Singh, Uppal, Karan, Olling, Janne Damm, Kjaergaard, Kristian, Kurpiers, Thomas, Schnabel, Meike, Reich, Diana, Glock, Philipp, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Hehn, Yvonne, Killian, Steffen, Viet, Laura, Runz, Josefine, Faltinger, Frank, Tabrizi, Mohammad, Abel, Kristin Laura, Breinholt, Vibeke Miller, Singel, Stina M, Sprogøe, Kennett, Punnonen, Juha
Publicado 2022