A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells

por Nagarkar-Jaiswal, Sonal, Manivannan, Sathiya N, Zuo, Zhongyuan, Bellen, Hugo J
Publicado 2017

Ubiquilins Regulate Autophagic Flux through mTOR Signaling and Lysosomal Acidification

por Şentürk, Mümine, Lin, Guang, Zuo, Zhongyuan, Mao, Dongxue, Watson, Emma, Mikos, Antonios G., Bellen, Hugo J.
Publicado 2019

Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia

por Wang, Liping, Lin, Guang, Zuo, Zhongyuan, Li, Yarong, Byeon, Seul Kee, Pandey, Akhilesh, Bellen, Hugo J.
Publicado 2022

Daam2 phosphorylation by CK2α negatively regulates Wnt activity during white matter development and injury

por Wang, Chih-Yen, Zuo, Zhongyuan, Jo, Juyeon, Kim, Kyoung In, Madamba, Christine, Ye, Qi, Jung, Sung Yun, Bellen, Hugo J., Lee, Hyun Kyoung
Publicado 2023

An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

por Li-Kroeger, David, Kanca, Oguz, Lee, Pei-Tseng, Cowan, Sierra, Lee, Michael T, Jaiswal, Manish, Salazar, Jose Luis, He, Yuchun, Zuo, Zhongyuan, Bellen, Hugo J
Publicado 2018

A genetic toolkit for tagging intronic MiMIC containing genes

por Nagarkar-Jaiswal, Sonal, DeLuca, Steven Z, Lee, Pei-Tseng, Lin, Wen-Wen, Pan, Hongling, Zuo, Zhongyuan, Lv, Jiangxing, Spradling, Allan C, Bellen, Hugo J
Publicado 2015

Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells

por Brown, Amanda M., Arancillo, Marife, Lin, Tao, Catt, Daniel R., Zhou, Joy, Lackey, Elizabeth P., Stay, Trace L., Zuo, Zhongyuan, White, Joshua J., Sillitoe, Roy V.
Publicado 2019

Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila

por Bosch, Justin A, Ugur, Berrak, Pichardo-Casas, Israel, Rabasco, Jordan, Escobedo, Felipe, Zuo, Zhongyuan, Brown, Ben, Celniker, Susan, Sinclair, David A, Bellen, Hugo J, Perrimon, Norbert
Publicado 2022

Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain

por Ye, Hui, Ojelade, Shamsideen A, Li-Kroeger, David, Zuo, Zhongyuan, Wang, Liping, Li, Yarong, Gu, Jessica YJ, Tepass, Ulrich, Rodal, Avital Adah, Bellen, Hugo J, Shulman, Joshua M
Publicado 2020

Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease

por Chouhan, Amit K., Guo, Caiwei, Hsieh, Yi-Chen, Ye, Hui, Senturk, Mumine, Zuo, Zhongyuan, Li, Yarong, Chatterjee, Shreyasi, Botas, Juan, Jackson, George R., Bellen, Hugo J., Shulman, Joshua M.
Publicado 2016

Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies

por Martelli, Felipe, Hernandes, Natalia H, Zuo, Zhongyuan, Wang, Julia, Wong, Ching-On, Karagas, Nicholas E, Roessner, Ute, Rupasinghe, Thusita, Robin, Charles, Venkatachalam, Kartik, Perry, Trent, Batterham, Philip, Bellen, Hugo J
Publicado 2022

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

por Kanca, Oguz, Zirin, Jonathan, Hu, Yanhui, Tepe, Burak, Dutta, Debdeep, Lin, Wen-Wen, Ma, Liwen, Ge, Ming, Zuo, Zhongyuan, Liu, Lu-Ping, Levis, Robert W, Perrimon, Norbert, Bellen, Hugo J
Publicado 2022

Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14)

por Lin, Guang, Tepe, Burak, McGrane, Geoff, Tipon, Regine C, Croft, Gist, Panwala, Leena, Hope, Amanda, Liang, Agnes JH, Zuo, Zhongyuan, Byeon, Seul Kee, Wang, Lily, Pandey, Akhilesh, Bellen, Hugo J
Publicado 2023

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

por Cunningham, Kathleen M, Maulding, Kirstin, Ruan, Kai, Senturk, Mumine, Grima, Jonathan C, Sung, Hyun, Zuo, Zhongyuan, Song, Helen, Gao, Junli, Dubey, Sandeep, Rothstein, Jeffrey D, Zhang, Ke, Bellen, Hugo J, Lloyd, Thomas E
Publicado 2020

cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis

por Ojelade, Shamsideen A., Lee, Tom V., Giagtzoglou, Nikolaos, Yu, Lei, Ugur, Berrak, Li, Yarong, Duraine, Lita, Zuo, Zhongyuan, Petyuk, Vlad, De Jager, Philip L., Bennett, David A., Arenkiel, Benjamin R., Bellen, Hugo J., Shulman, Joshua M.
Publicado 2019

The Daam2–VHL–Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation

por Ding, Xiaoyun, Jo, Juyeon, Wang, Chih-Yen, Cristobal, Carlo D., Zuo, Zhongyuan, Ye, Qi, Wirianto, Marvin, Lindeke-Myers, Aaron, Choi, Jong Min, Mohila, Carrie A., Kawabe, Hiroshi, Jung, Sung Yun, Bellen, Hugo J., Yoo, Seung-Hee, Lee, Hyun Kyoung
Publicado 2020

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

por Kanca, Oguz, Zirin, Jonathan, Garcia-Marques, Jorge, Knight, Shannon Marie, Yang-Zhou, Donghui, Amador, Gabriel, Chung, Hyunglok, Zuo, Zhongyuan, Ma, Liwen, He, Yuchun, Lin, Wen-Wen, Fang, Ying, Ge, Ming, Yamamoto, Shinya, Schulze, Karen L, Hu, Yanhui, Spradling, Allan C, Mohr, Stephanie E, Perrimon, Norbert, Bellen, Hugo J
Publicado 2019

A gene-specific T2A-GAL4 library for Drosophila

por Lee, Pei-Tseng, Zirin, Jonathan, Kanca, Oguz, Lin, Wen-Wen, Schulze, Karen L, Li-Kroeger, David, Tao, Rong, Devereaux, Colby, Hu, Yanhui, Chung, Verena, Fang, Ying, He, Yuchun, Pan, Hongling, Ge, Ming, Zuo, Zhongyuan, Housden, Benjamin E, Mohr, Stephanie E, Yamamoto, Shinya, Levis, Robert W, Spradling, Allan C, Perrimon, Norbert, Bellen, Hugo J
Publicado 2018

Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially

por Luo, Xi, Rosenfeld, Jill A., Yamamoto, Shinya, Harel, Tamar, Zuo, Zhongyuan, Hall, Melissa, Wierenga, Klaas J., Pastore, Matthew T., Bartholomew, Dennis, Delgado, Mauricio R., Rotenberg, Joshua, Lewis, Richard Alan, Emrick, Lisa, Bacino, Carlos A., Eldomery, Mohammad K., Coban Akdemir, Zeynep, Xia, Fan, Yang, Yaping, Lalani, Seema R., Lotze, Timothy, Lupski, James R., Lee, Brendan, Bellen, Hugo J., Wangler, Michael F.
Publicado 2017

Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling

por Marcogliese, Paul C., Dutta, Debdeep, Ray, Shrestha Sinha, Dang, Nghi D. P., Zuo, Zhongyuan, Wang, Yuchun, Lu, Di, Fazal, Fatima, Ravenscroft, Thomas A., Chung, Hyunglok, Kanca, Oguz, Wan, JiJun, Douine, Emilie D., Network, Undiagnosed Diseases, Pena, Loren D. M., Yamamoto, Shinya, Nelson, Stanley F., Might, Matthew, Meyer, Kathrin C., Yeo, Nan Cher, Bellen, Hugo J.
Publicado 2022