Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β(0)39-Globin Gene Editing and Induction of Fetal Hemoglobin

por Cosenza, Lucia Carmela, Zuccato, Cristina, Zurlo, Matteo, Gambari, Roberto, Finotti, Alessia
Publicado 2022

Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology

por Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Corradini, Roberto, Gambari, Roberto, Finotti, Alessia
Publicado 2019

Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR...

por Zurlo, Matteo, Romagnoli, Romeo, Oliva, Paola, Gasparello, Jessica, Finotti, Alessia, Gambari, Roberto
Publicado 2021

Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imi...

por Zurlo, Matteo, Romagnoli, Romeo, Oliva, Paola, Gasparello, Jessica, Finotti, Alessia, Gambari, Roberto
Publicado 2022

The Cystic Fibrosis Transmembrane Conductance Regulator Gene (CFTR) Is under Post-Transcriptional Control of microRNAs: Analysis of the Effects of agomiRNAs Mimicking miR-145-5p, m...

por Papi, Chiara, Gasparello, Jessica, Zurlo, Matteo, Cosenza, Lucia Carmela, Gambari, Roberto, Finotti, Alessia
Publicado 2023

Effects of Sirolimus Treatment on Fetal Hemoglobin Production and Response to SARS-CoV-2 Vaccination: A Case Report Study

por Gamberini, Maria Rita, Zuccato, Cristina, Zurlo, Matteo, Cosenza, Lucia Carmela, Finotti, Alessia, Gambari, Roberto
Publicado 2023

Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β(0)39-thalassemia patients

por Cosenza, Lucia Carmela, Gasparello, Jessica, Romanini, Nicola, Zurlo, Matteo, Zuccato, Cristina, Gambari, Roberto, Finotti, Alessia
Publicado 2021

Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibr...

por Papi, Chiara, Gasparello, Jessica, Zurlo, Matteo, Manicardi, Alex, Corradini, Roberto, Cabrini, Giulio, Gambari, Roberto, Finotti, Alessia
Publicado 2022

Production and Characterization of K562 Cellular Clones Hyper-Expressing the Gene Encoding α-Globin: Preliminary Analysis of Biomarkers Associated with Autophagy

por Zurlo, Matteo, Gasparello, Jessica, Cosenza, Lucia Carmela, Breveglieri, Giulia, Papi, Chiara, Zuccato, Cristina, Gambari, Roberto, Finotti, Alessia
Publicado 2023

Treatment of Erythroid Precursor Cells from β-Thalassemia Patients with Cinchona Alkaloids: Induction of Fetal Hemoglobin Production

por Zuccato, Cristina, Cosenza, Lucia Carmela, Zurlo, Matteo, Lampronti, Ilaria, Borgatti, Monica, Scapoli, Chiara, Gambari, Roberto, Finotti, Alessia
Publicado 2021

Teaching during COVID-19 pandemic in practical laboratory classes of applied biochemistry and pharmacology: A validated fast and simple protocol for detection of SARS-CoV-2 Spike s...

por Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Cosenza, Lucia Carmela, Breveglieri, Giulia, Zuccato, Cristina, Gambari, Roberto, Finotti, Alessia
Publicado 2022

Combined Treatment of Cancer Cells Using Allyl Palladium Complexes Bearing Purine-Based NHC Ligands and Molecules Targeting MicroRNAs miR-221-3p and miR-222-3p: Synergistic Effects...

por Tupini, Chiara, Zurlo, Matteo, Gasparello, Jessica, Lodi, Irene, Finotti, Alessia, Scattolin, Thomas, Visentin, Fabiano, Gambari, Roberto, Lampronti, Ilaria
Publicado 2023

Cationic Calix[4]arene Vectors to Efficiently Deliver AntimiRNA Peptide Nucleic Acids (PNAs) and miRNA Mimics

por Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Volpi, Stefano, Gambari, Roberto, Corradini, Roberto, Casnati, Alessandro, Sansone, Francesco, Finotti, Alessia
Publicado 2023

The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathie...

por Gambari, Roberto, Zuccato, Cristina, Cosenza, Lucia Carmela, Zurlo, Matteo, Gasparello, Jessica, Finotti, Alessia, Gamberini, Maria Rita, Prosdocimi, Marco
Publicado 2023

Effects of Sulforaphane on SARS-CoV-2 infection and NF-κB dependent expression of genes involved in the COVID-19 'cytokine storm'

por Gasparello, Jessica, Marzaro, Giovanni, Papi, Chiara, Gentili, Valentina, Rizzo, Roberta, Zurlo, Matteo, Scapoli, Chiara, Finotti, Alessia, Gambari, Roberto
Publicado 2023

Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis

por Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Gambari, Laura, Rozzi, Andrea, Manicardi, Alex, Corradini, Roberto, Gambari, Roberto, Finotti, Alessia
Publicado 2022

MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of A...

por Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Gambari, Laura, Manicardi, Alex, Rozzi, Andrea, Ferrarini, Matteo, Corradini, Roberto, Gambari, Roberto, Finotti, Alessia
Publicado 2022

Decrease in α-Globin and Increase in the Autophagy-Activating Kinase ULK1 mRNA in Erythroid Precursors from β-Thalassemia Patients Treated with Sirolimus

por Zurlo, Matteo, Zuccato, Cristina, Cosenza, Lucia Carmela, Gasparello, Jessica, Gamberini, Maria Rita, Stievano, Alice, Fortini, Monica, Prosdocimi, Marco, Finotti, Alessia, Gambari, Roberto
Publicado 2023

The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated wi...

por Zuccato, Cristina, Cosenza, Lucia Carmela, Zurlo, Matteo, Breveglieri, Giulia, Bianchi, Nicoletta, Lampronti, Ilaria, Gasparello, Jessica, Scapoli, Chiara, Borgatti, Monica, Finotti, Alessia, Gambari, Roberto
Publicado 2023

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

por Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Cacciari, Barbara, Balzarini, Jan, Liekens, Sandra, Hamel, Ernest, Brancale, Andrea, Ferla, Salvatore, Manfredini, Stefano, Zurlo, Matteo, Finotti, Alessia, Gambari, Roberto
Publicado 2020