Correction of copy number induced false positives in CRISPR screens

por de Weck, Antoine, Golji, Javad, Jones, Michael D., Korn, Joshua M., Billy, Eric, McDonald, E. Robert, Schmelzle, Tobias, Bitter, Hans, Kauffmann, Audrey
Publicado 2018

Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens

por Montazeri, Hesam, Coto-Llerena, Mairene, Bianco, Gaia, Zangene, Ehsan, Taha-Mehlitz, Stephanie, Paradiso, Viola, Srivatsa, Sumana, de Weck, Antoine, Roma, Guglielmo, Lanzafame, Manuela, Bolli, Martin, Beerenwinkel, Niko, von Flüe, Markus, Terracciano, Luigi M, Piscuoglio, Salvatore, Ng, Charlotte K Y
Publicado 2021

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway

por Dafflon, Caroline, Gaulis, Swann, Barys, Louise, Kapur, Karen, Cornacchione, Vanessa, Schukur, Lina, Bergling, Sebastian, Traggiai, Elisabetta, Jansky, Selina, Hellmann, Leon, Engstler, Barbara Schacher, Kerr, Grainne, de Weck, Antoine, Ruddy, David A., Naumann, Ulrike, Stauffer, Frédéric, Gaul, Christoph, Lin, Ying, Billy, Eric, Weiss, Andreas, Hofmann, Francesco, Ito, Moriko, Tiedt, Ralph
Publicado 2020

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer

por Witwicki, Robert M., Ekram, Muhammad B., Qiu, Xintao, Janiszewska, Michalina, Shu, Shaokun, Kwon, Mijung, Trinh, Anne, Frias, Elizabeth, Ramadan, Nadire, Hoffman, Greg, Yu, Kristine, Xie, Yingtian, McAllister, Gregory, McDonald, Rob, Golji, Javad, Schlabach, Michael, deWeck, Antoine, Keen, Nicholas, Chan, Ho Man, Ruddy, David, Rejtar, Tomas, Sovath, Sosathya, Silver, Serena, Sellers, William R., Jagani, Zainab, Hogarty, Michael D., Roberts, Charles, Brown, Myles, Stegmaier, Kimberly, Long, Henry, Shivdasani, Ramesh A., Pellman, David, Polyak, Kornelia
Publicado 2018

TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts

por Grauel, Angelo L., Nguyen, Beverly, Ruddy, David, Laszewski, Tyler, Schwartz, Stephanie, Chang, Jonathan, Chen, Julie, Piquet, Michelle, Pelletier, Marc, Yan, Zheng, Kirkpatrick, Nathaniel D., Wu, Jincheng, deWeck, Antoine, Riester, Markus, Hims, Matt, Geyer, Felipe Correa, Wagner, Joel, MacIsaac, Kenzie, Deeds, James, Diwanji, Rohan, Jayaraman, Pushpa, Yu, Yenyen, Simmons, Quincey, Weng, Shaobu, Raza, Alina, Minie, Brian, Dostalek, Mirek, Chikkegowda, Pavitra, Ruda, Vera, Iartchouk, Oleg, Chen, Naiyan, Thierry, Raphael, Zhou, Joseph, Pruteanu-Malinici, Iulian, Fabre, Claire, Engelman, Jeffrey A., Dranoff, Glenn, Cremasco, Viviana
Publicado 2020