Spatial Genome Organization: From Development to Disease

por Sivakumar, Aishwarya, de las Heras, Jose I., Schirmer, Eric C.
Publicado 2019

Optimization of DamID for use in primary cultures of mouse hepatocytes

por Gatticchi, Leonardo, de las Heras, Jose I., Roberti, Rita, Schirmer, Eric C.
Publicado 2019

TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation

por Batrakou, Dzmitry G., de las Heras, Jose I., Czapiewski, Rafal, Mouras, Rabah, Schirmer, Eric C.
Publicado 2015

Tm7sf2 Disruption Alters Radial Gene Positioning in Mouse Liver Leading to Metabolic Defects and Diabetes Characteristics

por Gatticchi, Leonardo, de las Heras, Jose I., Sivakumar, Aishwarya, Zuleger, Nikolaj, Roberti, Rita, Schirmer, Eric C.
Publicado 2020

Tissue-specific NETs alter genome organization and regulation even in a heterologous system

por de las Heras, Jose I., Zuleger, Nikolaj, Batrakou, Dzmitry G., Czapiewski, Rafal, Kerr, Alastair R. W., Schirmer, Eric C.
Publicado 2017

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

por Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Sivakumar, Aishwarya, Kerr, Alastair R.W., Schirmer, Eric C.
Publicado 2017

Tissue specificity in the nuclear envelope supports its functional complexity

por de las Heras, Jose I, Meinke, Peter, Batrakou, Dzmitry G, Srsen, Vlastimil, Zuleger, Nikolaj, Kerr, Alastair RW, Schirmer, Eric C
Publicado 2013

Metabolic, fibrotic and splicing pathways are all altered in Emery-Dreifuss muscular dystrophy spectrum patients to differing degrees

por de las Heras, Jose I, Todorow, Vanessa, Krečinić-Balić, Lejla, Hintze, Stefan, Czapiewski, Rafal, Webb, Shaun, Schoser, Benedikt, Meinke, Peter, Schirmer, Eric C
Publicado 2022

NET23/STING Promotes Chromatin Compaction from the Nuclear Envelope

por Malik, Poonam, Zuleger, Nikolaj, de las Heras, Jose I., Saiz-Ros, Natalia, Makarov, Alexandr A., Lazou, Vassiliki, Meinke, Peter, Waterfall, Martin, Kelly, David A., Schirmer, Eric C.
Publicado 2014

Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

por Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Lê Thành, Phú, Booth, Daniel G., Kelly, David A., Webb, Shaun, Kerr, Alastair R.W., Schirmer, Eric C.
Publicado 2016

Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy

por Czapiewski, Rafal, Batrakou, Dzmitry G., de las Heras, Jose I., Carter, Roderick N., Sivakumar, Aishwarya, Sliwinska, Magdalena, Dixon, Charles R., Webb, Shaun, Lattanzi, Giovanna, Morton, Nicholas M., Schirmer, Eric C.
Publicado 2022

A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism

por Meinke, Peter, Kerr, Alastair R.W., Czapiewski, Rafal, de las Heras, Jose I., Dixon, Charles R., Harris, Elizabeth, Kölbel, Heike, Muntoni, Francesco, Schara, Ulrike, Straub, Volker, Schoser, Benedikt, Wehnert, Manfred, Schirmer, Eric C.
Publicado 2019

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery

por Zuleger, Nikolaj, Boyle, Shelagh, Kelly, David A, de las Heras, Jose I, Lazou, Vassiliki, Korfali, Nadia, Batrakou, Dzmitry G, Randles, K Natalie, Morris, Glenn E, Harrison, David J, Bickmore, Wendy A, Schirmer, Eric C
Publicado 2013

STING nuclear partners contribute to innate immune signaling responses

por Dixon, Charles R., Malik, Poonam, de las Heras, Jose I., Saiz-Ros, Natalia, de Lima Alves, Flavia, Tingey, Mark, Gaunt, Eleanor, Richardson, A. Christine, Kelly, David A., Goldberg, Martin W., Towers, Greg J., Yang, Weidong, Rappsilber, Juri, Digard, Paul, Schirmer, Eric C.
Publicado 2021

Repo-Man/PP1 regulates heterochromatin formation in interphase

por de Castro, Inês J., Budzak, James, Di Giacinto, Maria L., Ligammari, Lorena, Gokhan, Ezgi, Spanos, Christos, Moralli, Daniela, Richardson, Christine, de las Heras, Jose I., Salatino, Silvia, Schirmer, Eric C., Ullman, Katharine S., Bickmore, Wendy A., Green, Catherine, Rappsilber, Juri, Lamble, Sarah, Goldberg, Martin W., Vinciotti, Veronica, Vagnarelli, Paola
Publicado 2017