Editorial: Gene therapy 2.0: Biotechnology for circuit engineering and complex therapeutic approaches

por Quintino, Luís, de Almeida, Luís Pereira, Lundberg, Cecilia
Publicado 2022

Mesenchymal stromal cells to fight SARS-CoV-2: Taking advantage of a pleiotropic therapy

por Barros, Inês, Silva, António, de Almeida, Luís Pereira, Miranda, Catarina Oliveira
Publicado 2021

Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

por Marcelo, Adriana, Koppenol, Rebekah, de Almeida, Luís Pereira, Matos, Carlos A., Nóbrega, Clévio
Publicado 2021

Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

por Nóbrega, Clévio, Nascimento-Ferreira, Isabel, Onofre, Isabel, Albuquerque, David, Hirai, Hirokazu, Déglon, Nicole, de Almeida, Luís Pereira
Publicado 2013

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

por Ferreira-Marques, Marisa, Aveleira, Célia A., Carmo-Silva, Sara, Botelho, Mariana, de Almeida, Luís Pereira, Cavadas, Cláudia
Publicado 2016

Using genetically modified extracellular vesicles as a non-invasive strategy to evaluate brain-specific cargo

por Rufino-Ramos, David, Lule, Sevda, Mahjoum, Shadi, Ughetto, Stefano, Bragg, D. Cristopher, de Almeida, Luís Pereira, Breakefield, Xandra O., Breyne, Koen
Publicado 2022

Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles

por Conceição, Mariana, Mendonça, Liliana, Nóbrega, Clévio, Gomes, Célia, Costa, Pedro, Hirai, Hirokazu, Moreira, João Nuno, Lima, Maria C., Manjunath, N., de Almeida, Luís Pereira
Publicado 2016

Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment

por Onofre, Isabel, Mendonça, Nuno, Lopes, Sara, Nobre, Rui, de Melo, Joana Barbosa, Carreira, Isabel Marques, Januário, Cristina, Gonçalves, António Freire, de Almeida, Luis Pereira
Publicado 2016

Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases

por Brás, João, Henriques, Daniel, Moreira, Ricardo, Santana, Magda M., Silva-Pedrosa, Rita, Adão, Diana, Braz, Sandra, Álvaro, Ana Rita, de Almeida, Luís Pereira, Mendonça, Liliana S.
Publicado 2022

Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus Ultracentrifugation

por Soares, Maria, Pinto, Maria M., Nobre, Rui Jorge, de Almeida, Luís Pereira, da Graça Rasteiro, Maria, Almeida-Santos, Teresa, Ramalho-Santos, João, Sousa, Ana Paula
Publicado 2023

Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease

por Miranda, Catarina Oliveira, Nobre, Rui Jorge, Paiva, Vitor Hugo, Duarte, João Valente, Castelhano, João, Petrella, Lorena Itatí, Sereno, José, Santana, Magda, Afonso, Sónia, Januário, Cristina, Castelo-Branco, Miguel, de Almeida, Luís Pereira
Publicado 2022

Extracellular communication between brain cells through functional transfer of Cre mRNA

por Rufino-Ramos, David, Leandro, Kevin, Perdigão, Pedro R.L., O’Brien, Killian, Pinto, Maria Manuel, Santana, Magda M., van Solinge, Thomas S, Mahjoum, Shadi, Breakefield, Xandra O, Breyne, Koen, de Almeida, Luís Pereira
Publicado 2023

Photodynamic disinfection of SARS-CoV-2 clinical samples using a methylene blue formulation

por Lobo, Catarina S., Rodrigues-Santos, Paulo, Pereira, Dina, Núñez, Jisette, Trêpa, João C. D., Sousa, David Lopes, Lourenço, Jorge Vaz, Coelho, Maria Filomena, de Almeida, Luis Pereira, da Cunha, José Saraiva, Arnaut, Luis G.
Publicado 2022

Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy

por Marcelo, Adriana, Afonso, Inês T., Afonso-Reis, Ricardo, Brito, David V. C., Costa, Rafael G., Rosa, Ana, Alves-Cruzeiro, João, Ferreira, Benedita, Henriques, Carina, Nobre, Rui J., Matos, Carlos A., de Almeida, Luís Pereira, Nóbrega, Clévio
Publicado 2021

A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia

por Martins, Mariana, Oliveira, Ana Rafaela, Martins, Solange, Vieira, José Pedro, Perdigão, Pedro, Fernandes, Ana Rita, de Almeida, Luís Pereira, Palma, Paulo Jorge, Sequeira, Diana Bela, Santos, João Miguel Marques, Duque, Frederico, Oliveira, Guiomar, Cardoso, Ana Luísa, Peça, João, Seabra, Catarina Morais
Publicado 2023

The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors

por Hengel, Holger, Martus, Peter, Faber, Jennifer, Giunit, Paola, Garcia-Moreno, Hector, Solanky, Nita, Klockgether, Thomas, Reetz, Kathrin, van de Warrenburg, Bart P., Santana, Magda M., Silva, Patrick, Cunha, Inês, de Almeida, Luís Pereira, Timmann, Dagmar, Infante, Jon, de Vries, Jeroen, Lima, Manuela, Pires, Paula, Bushara, Khalaf, Jacobi, Heike, Onyike, Chiadi, Schmahmann, Jeremy D., Hübener-Schmid, Jeannette, Synofzik, Matthis, Schöls, Ludger
Publicado 2022

Stage-dependent biomarker changes in spinocerebellar ataxia type 3

por Faber, Jennifer, Berger, Moritz, Carlo, Wilke, Hübener-Schmid, Jeannette, Schaprian, Tamara, Santana, Magda M, Grobe-Einsler, Marcus, Onder, Dement, Koyak, Berkan, Giunti, Paola, Garcia-Moreno, Hector, Gonzalez-Robles, Cristina, Lima, Manuela, Raposo, Mafalda, Melo, Ana Rosa Vieira, de Almeida, Luis Pereira, Silva, Patrick, Pinto, Maria M, van de Warrenburg, Bart P., van Gaalen, Judith, de Vries, Jeroen, Jeroen, Oz, Gulin, Joers, James M., Synofzik, Matthis, Schöls, Ludger, Riess, Olaf, Infante, Jon, Manrique, Leire, Timmann, Dagmar, Thieme, Andreas, Jacobi, Heike, Reetz, Kathrin, Dogan, Imis, Onyike, Chiadikaobi, Povazan, Michal, Schmahmann, Jeremy, Ratai, Eva-Maria, Schmid, Matthias, Klockgether, Thomas
Publicado 2023