Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion

por Jalan-Sakrikar, Nidhi, De Assuncao, Thiago M., Lu, Jie, Almada, Luciana L., Lomberk, Gwen, Fernandez-Zapico, Martin E., Urrutia, Raul, Huebert, Robert C.
Publicado 2016

Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry

por Pollin, Gareth, De Assuncao, Thiago M., Doria Jorge, Salomao, Chi, Young-In, Charlesworth, M. Cristine, Madden, Benjamin, Iovanna, Juan, Zimmermann, Michael T., Urrutia, Raul, Lomberk, Gwen
Publicado 2023

Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers

por Chi, Young-In, Stodola, Timothy J., De Assuncao, Thiago M., Leverence, Elise N., Smith, Brian C., Volkman, Brian F., Mathison, Angela J., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul
Publicado 2022

The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage

por Leonard, Phoebe H., Grzenda, Adrienne, Mathison, Angela, Morbeck, Dean E., Fredrickson, Jolene R., de Assuncao, Thiago M., Christensen, Trace, Salisbury, Jeffrey, Calvo, Ezequiel, Iovanna, Juan, Coddington, Charles C., Urrutia, Raul, Lomberk, Gwen
Publicado 2015

Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1‐like (DOT1L) and partnering complexes involved in leukemogenesis...

por Stodola, Timothy J., Chi, Young‐In, De Assuncao, Thiago M., Leverence, Elise N., Tripathi, Swarnendu, Dsouza, Nikita R., Mathison, Angela J., Volkman, Brian F., Smith, Brian C., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul
Publicado 2021

Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction

por Chi, Young-In, Stodola, Timothy J., De Assuncao, Thiago M., Levrence, Elise N., Tripathi, Swarnendu, Dsouza, Nikita R., Mathison, Angela J., Basel, Donald G., Volkman, Brian F., Smith, Brian C., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul
Publicado 2021

Correction to: Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction

por Chi, Young-In, Stodola, Timothy J., De Assuncao, Thiago M., Levrence, Elise N., Tripathi, Swarnendu, Dsouza, Nikita R., Mathison, Angela J., Basel, Donald G., Volkman, Brian F., Smith, Brian C., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul
Publicado 2021

Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Cholangiocytes

por De Assuncao, Thiago M., Sun, Yan, Jalan-Sakrikar, Nidhi, Drinane, Mary, Huang, Bing Q., Li, Ying, Davila, Jaime I., Wang, Ruisi, O’Hara, Steven P., Lomberk, Gwen A., Urrutia, Raul A., Ikeda, Yasuhiro, Huebert, Robert C.
Publicado 2015

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis

por Martin-Mateos, Rosa, De Assuncao, Thiago M., Arab, Juan Pablo, Jalan-Sakrikar, Nidhi, Yaqoob, Usman, Greuter, Thomas, Verma, Vikas K., Mathison, Angela J., Cao, Sheng, Lomberk, Gwen, Mathurin, Philippe, Urrutia, Raul, Huebert, Robert C., Shah, Vijay H.
Publicado 2018

Development and Characterization of Cholangioids from Normal and Diseased Human Cholangiocytes as an In Vitro Model to Study Primary Sclerosing Cholangitis

por Loarca, Lorena, De Assuncao, Thiago M., Jalan-Sakrikar, Nidhi, Bronk, Steve, Krishan, Anuradha, Huang, Bing, Morton, Leslie, Trussoni, Christy, Bonilla, Lorena Marcano, Krueger, Eugene, O’Hara, Steve, Splinter, Patrick, Shi, Guang, Pisarello, María José Lorenzo, Gores, Gregory J., Huebert, Robert C., LaRusso, Nicholas F.
Publicado 2017

Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation

por Jalan‐Sakrikar, Nidhi, De Assuncao, Thiago M., Navarro‐Corcuera, Amaia, Hamdan, Feda H., Loarca, Lorena, Kirkeby, Lindsey A., Resch, Zachary T., O’Hara, Steven P., Juran, Brian D., Lazaridis, Konstantinos N., Rosen, Charles B., Heimbach, Julie K., Taner, Timucin, Shah, Vijay H., LaRusso, Nicholas F., Huebert, Robert C.
Publicado 2021

Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy

por Lu, Jie, Zhou, Yingqun, Hu, Tianyuan, Zhang, Hui, Shen, Miao, Cheng, Ping, Dai, Weiqi, Wang, Fan, Chen, Kan, Zhang, Yan, Wang, Chengfeng, Li, Jingjing, Zheng, Yuanyuan, Yang, Jing, Zhu, Rong, Wang, Jianrong, Lu, Wenxia, Zhang, Huawei, Wang, Junshan, Xia, Yujing, De Assuncao, Thiago M., Jalan-Sakrikar, Nidhi, Huebert, Robert C., Bin Zhou, Guo, Chuanyong
Publicado 2016