Sex, drugs, and heart failure: a sex‐sensitive review of the evidence base behind current heart failure clinical guidelines

por Levinsson, Anna, Dubé, Marie‐Pierre, Tardif, Jean‐Claude, de Denus, Simon
Publicado 2018

A systematic review and meta-analysis of the impact of mineralocorticoid receptor antagonists on glucose homeostasis

por Korol, Sandra, Mottet, Fannie, Perreault, Sylvie, Baker, William L., White, Michel, de Denus, Simon
Publicado 2017

Construction of a femininity score in the UK Biobank and its association with angina diagnosis prior to myocardial infarction

por Levinsson, Anna, de Denus, Simon, Sandoval, Johanna, Lemieux Perreault, Louis-Philippe, Rouleau, Joëlle, Tardif, Jean-Claude, Hussin, Julie, Dubé, Marie-Pierre
Publicado 2022

Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation

por Iannino, Nadia, Nasri, Amine, Räkel, Agnès, Ducharme, Anique, Lachance, Kim, Racine, Normand, de Denus, Simon, Tremblay-Gravel, Maxime, Fortier, Annik, White, Michel
Publicado 2018

Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof‐of‐concept study

por Meloche, Maxime, Leclair, Grégoire, Jutras, Martin, Oussaïd, Essaïd, Gaulin, Marie‐Josée, Mongrain, Ian, Busseuil, David, Tardif, Jean‐Claude, Dubé, Marie‐Pierre, de Denus, Simon
Publicado 2022

Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure

por Kassem, Imad, Sanche, Steven, Li, Jun, Bonnefois, Guillaume, Dubé, Marie‐Pierre, Rouleau, Jean‐Lucien, Tardif, Jean‐Claude, White, Michel, Turgeon, Jacques, Nekka, Fahima, de Denus, Simon
Publicado 2020

CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction

por de Denus, Simon, Rouleau, Jean L., Mann, Douglas L., Huggins, Gordon S., Pereira, Naveen L., Shah, Svati H., Cappola, Thomas P., Fouodjio, René, Mongrain, Ian, Dubé, Marie-Pierre
Publicado 2017

Comparative Effectiveness and Safety of Low-Dose Oral Anticoagulants in Patients With Atrial Fibrillation

por Perreault, Sylvie, Dragomir, Alice, Côté, Robert, Lenglet, Aurélie, de Denus, Simon, Dorais, Marc, White-Guay, Brian, Brophy, James, Schnitzer, Mireille E., Dubé, Marie-Pierre, Tardif, Jean-Claude
Publicado 2022

Impact of amiodarone use on metoprolol concentrations, α‐OH‐metoprolol concentrations, metoprolol dosing and heart rate: A cross‐sectional study

por Robert, Sabrina, Pilon, Marc‐Olivier, Oussaïd, Essaïd, Meloche, Maxime, Leclair, Grégoire, Jutras, Martin, Gaulin, Marie‐Josée, Mongrain, Ian, Busseuil, David, Tardif, Jean‐Claude, Dubé, Marie‐Pierre, de Denus, Simon
Publicado 2023

A genetic model of ivabradine recapitulates results from randomized clinical trials

por Legault, Marc-André, Sandoval, Johanna, Provost, Sylvie, Barhdadi, Amina, Lemieux Perreault, Louis-Philippe, Shah, Sonia, Lumbers, R. Thomas, de Denus, Simon, Tyl, Benoit, Tardif, Jean-Claude, Dubé, Marie-Pierre
Publicado 2020

An association study of ABCG2 rs2231142 on the concentrations of allopurinol and its metabolites

por Pilon, Marc‐Olivier, Leclair, Grégoire, Oussaïd, Essaïd, St‐Jean, Isabelle, Jutras, Martin, Gaulin, Marie‐Josée, Mongrain, Ian, Busseuil, David, Rouleau, Jean Lucien, Tardif, Jean‐Claude, Dubé, Marie‐Pierre, de Denus, Simon
Publicado 2022

Impact of diabetes on serum biomarkers in heart failure with preserved ejection fraction: insights from the TOPCAT trial

por De Marco, Corrado, Claggett, Brian L., de Denus, Simon, Zile, Michael R., Huynh, Thao, Desai, Akshay S., Sirois, Martin G., Solomon, Scott D., Pitt, Bertram, Rouleau, Jean L., Pfeffer, Marc A., O'Meara, Eileen
Publicado 2021

Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved E...

por Vitiello, Damien, Harel, François, Touyz, Rhian M., Sirois, Martin G., Lavoie, Joel, Myers, Jonathan, Ducharme, Anique, Racine, Normand, O'Meara, Eileen, Gayda, Mathieu, Chabot-Blanchet, Malorie, Rouleau, Jean Lucien, de Denus, Simon, White, Michel
Publicado 2014

Females present higher dose‐adjusted drug concentrations of metoprolol and allopurinol/oxypurinol than males

por Hindi, Jessica, Pilon, Marc‐Olivier, Meloche, Maxime, Leclair, Grégoire, Oussaïd, Essaïd, St‐Jean, Isabelle, Jutras, Martin, Gaulin, Marie‐Josée, Mongrain, Ian, Busseuil, David, Rouleau, Jean Lucien, Tardif, Jean‐Claude, Dubé, Marie‐Pierre, de Denus, Simon
Publicado 2023

A Pharmacogenetic Investigation of Intravenous Furosemide in Decompensated Heart Failure: A Meta-Analysis of 3 Clinical Trials

por de Denus, Simon, Rouleau, Jean L, Mann, Douglas L., Huggins, Gordon S., Cappola, Thomas P., Shah, Svati H., Keleti, Julianna, Zada, Yassamin Feroz, Provost, Sylvie, Bardhadi, Amina, Phillips, Michael S., Normand, Valérie, Mongrain, Ian, Dubé, Marie-Pierre
Publicado 2016

A genetic association study of heart failure: more evidence for the role of BAG3 in idiopathic dilated cardiomyopathy

por de Denus, Simon, Mottet, Fannie, Korol, Sandra, Feroz Zada, Yassamin, Provost, Sylvie, Mongrain, Ian, Asselin, Géraldine, Oussaïd, Essaïd, Busseuil, David, Lettre, Guillaume, Rioux, John, Racine, Normand, O'Meara, Eileen, White, Michel, Rouleau, Jean, Tardif, Jean Claude, Dubé, Marie‐Pierre
Publicado 2020

Pharmacogenomic study of heart failure and candesartan response from the CHARM programme

por Dubé, Marie‐Pierre, Chazara, Olympe, Lemaçon, Audrey, Asselin, Géraldine, Provost, Sylvie, Barhdadi, Amina, Lemieux Perreault, Louis‐Philippe, Mongrain, Ian, Wang, Quanli, Carss, Keren, Paul, Dirk S., Cunningham, Jonathan W., Rouleau, Jean, Solomon, Scott D., McMurray, John J.V., Yusuf, Salim, Granger, Chris B., Haefliger, Carolina, de Denus, Simon, Tardif, Jean‐Claude
Publicado 2022

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

por Auer, Paul L., Teumer, Alexander, Schick, Ursula, O’Shaughnessy, Andrew, Lo, Ken Sin, Chami, Nathalie, Carlson, Chris, de Denus, Simon, Dubé, Marie-Pierre, Haessler, Jeff, Jackson, Rebecca D., Kooperberg, Charles, Perreault, Louis-Philippe Lemieux, Nauck, Matthias, Peters, Ulrike, Rioux, John D., Schmidt, Frank, Turcot, Valérie, Völker, Uwe, Völzke, Henry, Greinacher, Andreas, Hsu, Li, Tardif, Jean-Claude, Diaz, George A., Reiner, Alexander P., Lettre, Guillaume
Publicado 2014

Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT

por Dubé, Marie-Pierre, Legault, Marc-André, Lemaçon, Audrey, Lemieux Perreault, Louis-Philippe, Fouodjio, René, Waters, David D., Kouz, Simon, Pinto, Fausto J., Maggioni, Aldo P., Diaz, Rafael, Berry, Colin, Koenig, Wolfgang, Lopez-Sendon, Jose, Gamra, Habib, Kiwan, Ghassan S., Asselin, Géraldine, Provost, Sylvie, Barhdadi, Amina, Sun, Maxine, Cossette, Mariève, Blondeau, Lucie, Mongrain, Ian, Dubois, Anick, Rhainds, David, Bouabdallaoui, Nadia, Samuel, Michelle, de Denus, Simon, L’Allier, Philippe L., Guertin, Marie-Claude, Roubille, François, Tardif, Jean-Claude
Publicado 2021

Genetics of symptom remission in outpatients with COVID-19

por Dubé, Marie-Pierre, Lemaçon, Audrey, Barhdadi, Amina, Lemieux Perreault, Louis-Philippe, Oussaïd, Essaïd, Asselin, Géraldine, Provost, Sylvie, Sun, Maxine, Sandoval, Johanna, Legault, Marc-André, Mongrain, Ian, Dubois, Anick, Valois, Diane, Dedelis, Emma, Lousky, Jennifer, Choi, Julie, Goulet, Elisabeth, Savard, Christiane, Chicoine, Lea-Mei, Cossette, Mariève, Chabot-Blanchet, Malorie, Guertin, Marie-Claude, de Denus, Simon, Bouabdallaoui, Nadia, Marchand, Richard, Bassevitch, Zohar, Nozza, Anna, Gaudet, Daniel, L’Allier, Philippe L., Hussin, Julie, Boivin, Guy, Busseuil, David, Tardif, Jean-Claude
Publicado 2021