Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation

por Torres-Guzmán, Raquel, Ganado, Maria Patricia, Mur, Cecilia, Marugan, Carlos, Baquero, Carmen, Yang, Yanzhu, Zeng, Yi, Bian, Huimin, Du, Jian, de Dios, Alfonso, Puig, Oscar, Lallena, María José
Publicado 2022

Preclinical characterization of abemaciclib in hormone receptor positive breast cancer

por Torres-Guzmán, Raquel, Calsina, Bruna, Hermoso, Ana, Baquero, Carmen, Alvarez, Beatriz, Amat, Joaquín, McNulty, Ann M., Gong, Xueqian, Boehnke, Karsten, Du, Jian, de Dios, Alfonso, Beckmann, Richard P., Buchanan, Sean, Lallena, María José
Publicado 2017

Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

por Gelbert, Lawrence M., Cai, Shufen, Lin, Xi, Sanchez-Martinez, Concepcion, del Prado, Miriam, Lallena, Maria Jose, Torres, Raquel, Ajamie, Rose T., Wishart, Graham N., Flack, Robert Steven, Neubauer, Blake Lee, Young, Jamie, Chan, Edward M., Iversen, Philip, Cronier, Damien, Kreklau, Emiko, de Dios, Alfonso
Publicado 2014

Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy

por Gharbi, Severine Isabelle, Pelletier, Laura A., Espada, Alfonso, Gutiérrez, Jesus, Sanfeliciano, Sonia Maria Gutiérrez, Rauch, Charles T., Ganado, Maria Patricia, Baquero, Carmen, Zapatero, Elisabet, Zhang, Aiping, Benach, Jordi, Russell, Anna-Maria, Cano, Leticia, Gomez, Sandra, Broughton, Howard, Pulliam, Nicholas, Perez, Carmen Maria, Torres, Raquel, Debets, Marjoke F., de Dios, Alfonso, Puig, Oscar, Hilgers, Mark T., Lallena, Maria Jose
Publicado 2022

Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy

por Gharbi, Severine Isabelle, Pelletier, Laura A., Espada, Alfonso, Gutiérrez, Jesus, Sanfeliciano, Sonia Maria Gutiérrez, Rauch, Charles T., Ganado, Maria Patricia, Baquero, Carmen, Zapatero, Elisabet, Zhang, Aiping, Benach, Jordi, Russell, Anna-Maria, Cano, Leticia, Gomez, Sandra, Broughton, Howard, Pulliam, Nicholas, Perez, Carmen Maria, Torres, Raquel, Debets, Marjoke F., de Dios, Alfonso, Puig, Oscar, Hilgers, Mark T., Lallena, Maria Jose
Publicado 2022