Optimized workflow for single-cell transcriptomics on infectious diseases including COVID-19

por De Domenico, Elena, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Becker, Matthias, Händler, Kristian, Schultze, Joachim L.
Publicado 2020

Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing

por De Domenico, Elena, Owens, Nick D.L., Grant, Ian M., Gomes-Faria, Rosa, Gilchrist, Michael J.
Publicado 2015

Neutrophils in COVID-19

por Reusch, Nico, De Domenico, Elena, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Baßler, Kevin, Schultze, Joachim L., Aschenbrenner, Anna C.
Publicado 2021

Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells

por Peñailillo, Johany, Palacios, Miriam, Mounieres, Constanza, Muñoz, Rosana, Slater, Paula G., De Domenico, Elena, Patrushev, Ilya, Gilchrist, Mike, Larraín, Juan
Publicado 2021

High-resolution analysis of gene activity during the Xenopus mid-blastula transition

por Collart, Clara, Owens, Nick D. L., Bhaw-Rosun, Leena, Cooper, Brook, De Domenico, Elena, Patrushev, Ilya, Sesay, Abdul K., Smith, James N., Smith, James C., Gilchrist, Michael J.
Publicado 2014

A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation

por Hansen, Jan N, Kaiser, Fabian, Leyendecker, Philipp, Stüven, Birthe, Krause, Jens‐Henning, Derakhshandeh, Fatemeh, Irfan, Jaazba, Sroka, Tommy J, Preval, Kenley M, Desai, Paurav B, Kraut, Michael, Theis, Heidi, Drews, Anna‐Dorothee, De‐Domenico, Elena, Händler, Kristian, Pazour, Gregory J, Henderson, David J P, Mick, David U, Wachten, Dagmar
Publicado 2022

Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq

por Carraro, Caterina, Bonaguro, Lorenzo, Srinivasa, Rachana, van Uelft, Martina, Isakzai, Victoria, Schulte-Schrepping, Jonas, Gambhir, Prerna, Elmzzahi, Tarek, Montgomery, Jessica V., Hayer, Hannah, Li, Yuanfang, Theis, Heidi, Kraut, Michael, Mahbubani, Krishnaa T., Aschenbrenner, Anna C., König, Ireen, Fava, Eugenio, Fried, Hans-Ulrich, De Domenico, Elena, Beyer, Marc, Saglam, Adem, Schultze, Joachim L.
Publicado 2023

The discovAIR project: a roadmap towards the Human Lung Cell Atlas

por Luecken, Malte D., Zaragosi, Laure-Emmanuelle, Madissoon, Elo, Sikkema, Lisa, Firsova, Alexandra B., De Domenico, Elena, Kümmerle, Louis, Saglam, Adem, Berg, Marijn, Gay, Aurore C.A., Schniering, Janine, Mayr, Christoph H., Abalo, Xesús M., Larsson, Ludvig, Sountoulidis, Alexandros, Teichmann, Sarah A., van Eunen, Karen, Koppelman, Gerard H., Saeb-Parsy, Kourosh, Leroy, Sylvie, Powell, Pippa, Sarkans, Ugis, Timens, Wim, Lundeberg, Joakim, van den Berge, Maarten, Nilsson, Mats, Horváth, Peter, Denning, Jessica, Papatheodorou, Irene, Schultze, Joachim L., Schiller, Herbert B., Barbry, Pascal, Petoukhov, Ilya, Misharin, Alexander V., Adcock, Ian M., von Papen, Michael, Theis, Fabian J., Samakovlis, Christos, Meyer, Kerstin B., Nawijn, Martijn C.
Publicado 2022

Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation

por Baßler, Kevin, Fujii, Wataru, Kapellos, Theodore S., Dudkin, Erika, Reusch, Nico, Horne, Ari, Reiz, Benedikt, Luecken, Malte D., Osei-Sarpong, Collins, Warnat-Herresthal, Stefanie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Wagner, Allon, Günther, Patrick, Pizarro, Carmen, Schreiber, Tina, Knoll, Rainer, Holsten, Lisa, Kröger, Charlotte, De Domenico, Elena, Becker, Matthias, Händler, Kristian, Wohnhaas, Christian T., Baumgartner, Florian, Köhler, Meike, Theis, Heidi, Kraut, Michael, Wadsworth, Marc H., Hughes, Travis K., Ferreira, Humberto J., Hinkley, Emily, Kaltheuner, Ines H., Geyer, Matthias, Thiele, Christoph, Shalek, Alex K., Feißt, Andreas, Thomas, Daniel, Dickten, Henning, Beyer, Marc, Baum, Patrick, Yosef, Nir, Aschenbrenner, Anna C., Ulas, Thomas, Hasenauer, Jan, Theis, Fabian J., Skowasch, Dirk, Schultze, Joachim L.
Publicado 2022

Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease

por Kapellos, Theodore S., Baßler, Kevin, Fujii, Wataru, Nalkurthi, Christina, Schaar, Anna C., Bonaguro, Lorenzo, Pecht, Tal, Galvao, Izabela, Agrawal, Shobhit, Saglam, Adem, Dudkin, Erica, Frishberg, Amit, de Domenico, Elena, Horne, Arik, Donovan, Chantal, Kim, Richard Y., Gallego-Ortega, David, Gillett, Tessa E., Ansari, Meshal, Schulte-Schrepping, Jonas, Offermann, Nina, Antignano, Ignazio, Sivri, Burcu, Lu, Wenying, Eapen, Mathew S., van Uelft, Martina, Osei-Sarpong, Collins, van den Berge, Maarten, Donker, Hylke C., Groen, Harry J.M., Sohal, Sukhwinder S., Klein, Johanna, Schreiber, Tina, Feißt, Andreas, Yildirim, Ali Önder, Schiller, Herbert B., Nawijn, Martijn C., Becker, Matthias, Händler, Kristian, Beyer, Marc, Capasso, Melania, Ulas, Thomas, Hasenauer, Jan, Pizarro, Carmen, Theis, Fabian J., Hansbro, Philip M., Skowasch, Dirk, Schultze, Joachim L.
Publicado 2023

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

por Krämer, Benjamin, Knoll, Rainer, Bonaguro, Lorenzo, ToVinh, Michael, Raabe, Jan, Astaburuaga-García, Rosario, Schulte-Schrepping, Jonas, Kaiser, Kim Melanie, Rieke, Gereon J., Bischoff, Jenny, Monin, Malte B., Hoffmeister, Christoph, Schlabe, Stefan, De Domenico, Elena, Reusch, Nico, Händler, Kristian, Reynolds, Gary, Blüthgen, Nils, Hack, Gudrun, Finnemann, Claudia, Nischalke, Hans D., Strassburg, Christian P., Stephenson, Emily, Su, Yapeng, Gardner, Louis, Yuan, Dan, Chen, Daniel, Goldman, Jason, Rosenstiel, Philipp, Schmidt, Susanne V., Latz, Eicke, Hrusovsky, Kevin, Ball, Andrew J., Johnson, Joe M., Koenig, Paul-Albert, Schmidt, Florian I., Haniffa, Muzlifah, Heath, James R., Kümmerer, Beate M., Keitel, Verena, Jensen, Björn, Stubbemann, Paula, Kurth, Florian, Sander, Leif E., Sawitzki, Birgit, Aschenbrenner, Anna C., Schultze, Joachim L., Nattermann, Jacob
Publicado 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

por Aschenbrenner, Anna C., Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico, Baßler, Kevin, Saridaki, Maria, Knoll, Rainer, Pecht, Tal, Kapellos, Theodore S., Doulou, Sarandia, Kröger, Charlotte, Herbert, Miriam, Holsten, Lisa, Horne, Arik, Gemünd, Ioanna D., Rovina, Nikoletta, Agrawal, Shobhit, Dahm, Kilian, van Uelft, Martina, Drews, Anna, Lenkeit, Lena, Bruse, Niklas, Gerretsen, Jelle, Gierlich, Jannik, Becker, Matthias, Händler, Kristian, Kraut, Michael, Theis, Heidi, Mengiste, Simachew, De Domenico, Elena, Schulte-Schrepping, Jonas, Seep, Lea, Raabe, Jan, Hoffmeister, Christoph, ToVinh, Michael, Keitel, Verena, Rieke, Gereon, Talevi, Valentina, Skowasch, Dirk, Aziz, N. Ahmad, Pickkers, Peter, van de Veerdonk, Frank L., Netea, Mihai G., Schultze, Joachim L., Kox, Matthijs, Breteler, Monique M. B., Nattermann, Jacob, Koutsoukou, Antonia, Giamarellos-Bourboulis, Evangelos J., Ulas, Thomas
Publicado 2021

Swarm Learning for decentralized and confidential clinical machine learning

por Warnat-Herresthal, Stefanie, Schultze, Hartmut, Shastry, Krishnaprasad Lingadahalli, Manamohan, Sathyanarayanan, Mukherjee, Saikat, Garg, Vishesh, Sarveswara, Ravi, Händler, Kristian, Pickkers, Peter, Aziz, N. Ahmad, Ktena, Sofia, Tran, Florian, Bitzer, Michael, Ossowski, Stephan, Casadei, Nicolas, Herr, Christian, Petersheim, Daniel, Behrends, Uta, Kern, Fabian, Fehlmann, Tobias, Schommers, Philipp, Lehmann, Clara, Augustin, Max, Rybniker, Jan, Altmüller, Janine, Mishra, Neha, Bernardes, Joana P., Krämer, Benjamin, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, De Domenico, Elena, Siever, Christian, Kraut, Michael, Desai, Milind, Monnet, Bruno, Saridaki, Maria, Siegel, Charles Martin, Drews, Anna, Nuesch-Germano, Melanie, Theis, Heidi, Heyckendorf, Jan, Schreiber, Stefan, Kim-Hellmuth, Sarah, Nattermann, Jacob, Skowasch, Dirk, Kurth, Ingo, Keller, Andreas, Bals, Robert, Nürnberg, Peter, Rieß, Olaf, Rosenstiel, Philip, Netea, Mihai G., Theis, Fabian, Mukherjee, Sach, Backes, Michael, Aschenbrenner, Anna C., Ulas, Thomas, Breteler, Monique M. B., Giamarellos-Bourboulis, Evangelos J., Kox, Matthijs, Becker, Matthias, Cheran, Sorin, Woodacre, Michael S., Goh, Eng Lim, Schultze, Joachim L.
Publicado 2021

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

por Schulte-Schrepping, Jonas, Reusch, Nico, Paclik, Daniela, Baßler, Kevin, Schlickeiser, Stephan, Zhang, Bowen, Krämer, Benjamin, Krammer, Tobias, Brumhard, Sophia, Bonaguro, Lorenzo, De Domenico, Elena, Wendisch, Daniel, Grasshoff, Martin, Kapellos, Theodore S., Beckstette, Michael, Pecht, Tal, Saglam, Adem, Dietrich, Oliver, Mei, Henrik E., Schulz, Axel R., Conrad, Claudia, Kunkel, Désirée, Vafadarnejad, Ehsan, Xu, Cheng-Jian, Horne, Arik, Herbert, Miriam, Drews, Anna, Thibeault, Charlotte, Pfeiffer, Moritz, Hippenstiel, Stefan, Hocke, Andreas, Müller-Redetzky, Holger, Heim, Katrin-Moira, Machleidt, Felix, Uhrig, Alexander, Bosquillon de Jarcy, Laure, Jürgens, Linda, Stegemann, Miriam, Glösenkamp, Christoph R., Volk, Hans-Dieter, Goffinet, Christine, Landthaler, Markus, Wyler, Emanuel, Georg, Philipp, Schneider, Maria, Dang-Heine, Chantip, Neuwinger, Nick, Kappert, Kai, Tauber, Rudolf, Corman, Victor, Raabe, Jan, Kaiser, Kim Melanie, Vinh, Michael To, Rieke, Gereon, Meisel, Christian, Ulas, Thomas, Becker, Matthias, Geffers, Robert, Witzenrath, Martin, Drosten, Christian, Suttorp, Norbert, von Kalle, Christof, Kurth, Florian, Händler, Kristian, Schultze, Joachim L., Aschenbrenner, Anna C., Li, Yang, Nattermann, Jacob, Sawitzki, Birgit, Saliba, Antoine-Emmanuel, Sander, Leif Erik
Publicado 2020