Synthetic methodology towards allylic trans-cyclooctene-ethers enables modification of carbohydrates: bioorthogonal manipulation of the lac repressor

por de Geus, Mark A. R., Groenewold, G. J. Mirjam, Maurits, Elmer, Araman, Can, van Kasteren, Sander I.
Publicado 2020

Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

por van de Graaff, Michel J., Oosenbrug, Timo, Marqvorsen, Mikkel H. S., Nascimento, Clarissa R., de Geus, Mark A. R., Manoury, Bénédicte, Ressing, Maaike E., van Kasteren, Sander I.
Publicado 2020

A Lysosome-Targeted Tetrazine for Organelle-Specific Click-to-Release Chemistry in Antigen Presenting Cells

por Ligthart, Nina A.M., de Geus, Mark A.R., van de Plassche, Merel A.T., Torres García, Diana, Isendoorn, Marjolein M.E., Reinalda, Luuk, Ofman, Daniëlle, van Leeuwen, Tyrza, van Kasteren, Sander I.
Publicado 2023

DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling

por Stieger, Christian E., Park, Yerin, de Geus, Mark A. R., Kim, Dongju, Huhn, Christiane, Slenczka, J. Sophia, Ochtrop, Philipp, Müchler, Judith M., Süssmuth, Roderich D., Broichhagen, Johannes, Baik, Mu‐Hyun, Hackenberger, Christian P. R.
Publicado 2022

Fluorogenic Bifunctional trans‐Cyclooctenes as Efficient Tools for Investigating Click‐to‐Release Kinetics

por de Geus, Mark A. R., Maurits, Elmer, Sarris, Alexi J. C., Hansen, Thomas, Kloet, Max S., Kamphorst, Kiki, ten Hoeve, Wolter, Robillard, Marc S., Pannwitz, Andrea, Bonnet, Sylvestre A., Codée, Jeroen D. C., Filippov, Dmitri V., Overkleeft, Herman S., van Kasteren, Sander I.
Publicado 2020

Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes

por van der Gracht, Anouk M. F., de Geus, Mark A. R., Camps, Marcel G. M., Ruckwardt, Tracy J., Sarris, Alexi J. C., Bremmers, Jessica, Maurits, Elmer, Pawlak, Joanna B., Posthoorn, Michelle M., Bonger, Kimberly M., Filippov, Dmitri V., Overkleeft, Herman S., Robillard, Marc S., Ossendorp, Ferry, van Kasteren, Sander I.
Publicado 2018