Vaccines for the future: learning from human immunology

por De Gregorio, Ennio, Rappuoli, Rino
Publicado 2012

From empiricism to rational design: a personal perspective of the evolution of vaccine development

por De Gregorio, Ennio, Rappuoli, Rino
Publicado 2014

Vaccines for the 21st century

por Delany, Isabel, Rappuoli, Rino, De Gregorio, Ennio
Publicado 2014

Vaccine Adjuvants: Mode of Action

por De Gregorio, Ennio, Caproni, Elena, Ulmer, Jeffrey B.
Publicado 2013

Vaccines for the twenty-first century society

por Rappuoli, Rino, Mandl, Christian W., Black, Steven, De Gregorio, Ennio
Publicado 2011

Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design

por Rappuoli, Rino, Bottomley, Matthew J., D’Oro, Ugo, Finco, Oretta, De Gregorio, Ennio
Publicado 2016

Vaccinology in the post−COVID-19 era

por Rappuoli, Rino, De Gregorio, Ennio, Del Giudice, Giuseppe, Phogat, Sanjay, Pecetta, Simone, Pizza, Mariagrazia, Hanon, Emmanuel
Publicado 2021

Src Kinases Are Required for a Balanced Production of IL-12/IL-23 in Human Dendritic Cells Activated by Toll-Like Receptor Agonists

por Kuka, Mirela, Baronio, Roberta, Valentini, Sara, Monaci, Elisabetta, Muzzi, Alessandro, Aprea, Susanna, De Gregorio, Ennio, D'Oro, Ugo
Publicado 2010

Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

por Magini, Diletta, Giovani, Cinzia, Mangiavacchi, Simona, Maccari, Silvia, Cecchi, Raffaella, Ulmer, Jeffrey B., De Gregorio, Ennio, Geall, Andrew J., Brazzoli, Michela, Bertholet, Sylvie
Publicado 2016

Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells

por Cioncada, Rossella, Maddaluno, Marcella, Vo, Hoa Thi My, Woodruff, Matthew, Tavarini, Simona, Sammicheli, Chiara, Tortoli, Marco, Pezzicoli, Alfredo, De Gregorio, Ennio, Carroll, Michael C., D’Oro, Ugo, Piccioli, Diego
Publicado 2017

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

por Buonsanti, Cecilia, Balocchi, Cristiana, Harfouche, Carole, Corrente, Federica, Galli Stampino, Luisa, Mancini, Francesca, Tontini, Marta, Malyala, Padma, Bufali, Simone, Baudner, Barbara, De Gregorio, Ennio, Valiante, Nicholas M., O’Hagan, Derek T., Rappuoli, Rino, D’Oro, Ugo
Publicado 2016

Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination

por Corrado, Alessia, Donato, Paolo, Maccari, Silvia, Cecchi, Raffaella, Spadafina, Tiziana, Arcidiacono, Letizia, Tavarini, Simona, Sammicheli, Chiara, Laera, Donatello, Manetti, Andrea Guido Oreste, Ruggiero, Paolo, Galletti, Bruno, Nuti, Sandra, De Gregorio, Ennio, Bertholet, Sylvie, Seubert, Anja, Bagnoli, Fabio, Bensi, Giuliano, Chiarot, Emiliano
Publicado 2016

MF59- and Al(OH)(3)-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T...

por Monaci, Elisabetta, Mancini, Francesca, Lofano, Giuseppe, Bacconi, Marta, Tavarini, Simona, Sammicheli, Chiara, Arcidiacono, Letizia, Giraldi, Monica, Galletti, Bruno, Rossi Paccani, Silvia, Torre, Antonina, Fontana, Maria Rita, Grandi, Guido, de Gregorio, Ennio, Bensi, Giuliano, Chiarot, Emiliano, Nuti, Sandra, Bagnoli, Fabio, Soldaini, Elisabetta, Bertholet, Sylvie
Publicado 2015

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

por Knudsen, Niels Peter H., Olsen, Anja, Buonsanti, Cecilia, Follmann, Frank, Zhang, Yuan, Coler, Rhea N., Fox, Christopher B., Meinke, Andreas, D´Oro, Ugo, Casini, Daniele, Bonci, Alessandra, Billeskov, Rolf, De Gregorio, Ennio, Rappuoli, Rino, Harandi, Ali M., Andersen, Peter, Agger, Else Marie
Publicado 2016

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4(+) T Cells, and IL-17A

por Mancini, Francesca, Monaci, Elisabetta, Lofano, Giuseppe, Torre, Antonina, Bacconi, Marta, Tavarini, Simona, Sammicheli, Chiara, Arcidiacono, Letizia, Galletti, Bruno, Laera, Donatello, Pallaoro, Michele, Tuscano, Giovanna, Fontana, Maria Rita, Bensi, Giuliano, Grandi, Guido, Rossi-Paccani, Silvia, Nuti, Sandra, Rappuoli, Rino, De Gregorio, Ennio, Bagnoli, Fabio, Soldaini, Elisabetta, Bertholet, Sylvie
Publicado 2016

Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice

por Hekele, Armin, Bertholet, Sylvie, Archer, Jacob, Gibson, Daniel G, Palladino, Giuseppe, Brito, Luis A, Otten, Gillis R, Brazzoli, Michela, Buccato, Scilla, Bonci, Alessandra, Casini, Daniele, Maione, Domenico, Qi, Zhi-Qing, Gill, John E, Caiazza, Nicky C, Urano, Jun, Hubby, Bolyn, Gao, George F, Shu, Yuelong, De Gregorio, Ennio, Mandl, Christian W, Mason, Peter W, Settembre, Ethan C, Ulmer, Jeffrey B, Craig Venter, J, Dormitzer, Philip R, Rappuoli, Rino, Geall, Andrew J
Publicado 2013

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

por Francica, Joseph R., Sheng, Zizhang, Zhang, Zhenhai, Nishimura, Yoshiaki, Shingai, Masashi, Ramesh, Akshaya, Keele, Brandon F., Schmidt, Stephen D., Flynn, Barbara J., Darko, Sam, Lynch, Rebecca M., Yamamoto, Takuya, Matus-Nicodemos, Rodrigo, Wolinsky, David, Nason, Martha, Valiante, Nicholas M., Malyala, Padma, De Gregorio, Ennio, Barnett, Susan W., Singh, Manmohan, O'Hagan, Derek T., Koup, Richard A., Mascola, John R., Martin, Malcolm A., Kepler, Thomas B., Douek, Daniel C., Shapiro, Lawrence, Seder, Robert A.
Publicado 2015