Preclinical Models of Low-Grade Gliomas

por Dasgupta, Pushan, Balasubramanyian, Veerakumar, de Groot, John F., Majd, Nazanin K.
Publicado 2023

Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy

por Liang, Ji, Piao, Yuji, Henry, Verlene, Tiao, Ningyi, de Groot, John F.
Publicado 2015

Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma

por Park, Soon Young, Piao, Yuji, Thomas, Craig, Fuller, Gregory N., de Groot, John F.
Publicado 2016

Disparities along the glioblastoma clinical trials landscape

por Ludmir, Ethan B, Mandel, Jacob J, McAleer, Mary Frances, de Groot, John F
Publicado 2019

PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O(6)-methylguanine DNA damage in glioblastoma

por Wu, Shaofang, Li, Xiaolong, Gao, Feng, de Groot, John F, Koul, Dimpy, Yung, W K Alfred
Publicado 2021

Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice

por de Groot, John F., Fuller, Gregory, Kumar, Ashok J., Piao, Yuji, Eterovic, Karina, Ji, Yongjie, Conrad, Charles A.
Publicado 2010

Role of Neutrophils and Myeloid-Derived Suppressor Cells in Glioma Progression and Treatment Resistance

por Khan, Sabbir, Mittal, Sandeep, McGee, Kain, Alfaro-Munoz, Kristin D., Majd, Nazanin, Balasubramaniyan, Veerakumar, de Groot, John F.
Publicado 2020

Targeting intercellular adhesion molecule-1 prolongs survival in mice bearing bevacizumab-resistant glioblastoma

por Piao, Yuji, Henry, Verlene, Tiao, Ningyi, Park, Soon Young, Martinez-Ledesma, Juan, Dong, Jian Wen, Balasubramaniyan, Veerakumar, de Groot, John F.
Publicado 2017

The promise of DNA damage response inhibitors for the treatment of glioblastoma

por Majd, Nazanin K, Yap, Timothy A, Koul, Dimpy, Balasubramaniyan, Veerakumar, Li, Xiaolong, Khan, Sabbir, Gandy, Katilin S, Yung, W K Alfred, de Groot, John F
Publicado 2021

Aggressiveness of care at end of life in patients with high‐grade glioma

por Harrison, Rebecca A., Ou, Alexander, Naqvi, Syed M. A. A., Naqvi, Syed M., Weathers, Shiao‐Pei S., O'Brien, Barbara J., de Groot, John F., Bruera, Eduardo
Publicado 2021

Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas

por Ferguson, Sherise D, Zhou, Shouhao, Huse, Jason T, de Groot, John F, Xiu, Joanne, Subramaniam, Deepa S, Mehta, Shwetal, Gatalica, Zoran, Swensen, Jeffrey, Sanai, Nader, Spetzler, David, Heimberger, Amy B
Publicado 2018

A relative increase in circulating platelets following chemoradiation predicts for poor survival of patients with glioblastoma

por Boonyawan, Keeratikarn, Hess, Kenneth R., Yang, Jie, Long, Lihong, Wang, Qianghu, Ezhilarasan, Ravesanker, Auia, Alessandra, Alfaro-Munoz, Kristin D., de Groot, John F., Bhat, Krishna P., Sulman, Erik P.
Publicado 2017

Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis

por Lee, Jong-Ho, Liu, Rui, Li, Jing, Zhang, Chuanbao, Wang, Yugang, Cai, Qingsong, Qian, Xu, Xia, Yan, Zheng, Yanhua, Piao, Yuji, Chen, Qianming, de Groot, John F., Jiang, Tao, Lu, Zhimin
Publicado 2017

Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells

por Khan, Sabbir, Mahalingam, Rajasekaran, Sen, Shayak, Martinez-Ledesma, Emmanuel, Khan, Arshad, Gandy, Kaitlin, Lang, Frederick F., Sulman, Erik P., Alfaro-Munoz, Kristin D., Majd, Nazanin K., Balasubramaniyan, Veerakumar, de Groot, John F.
Publicado 2021

The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells

por Dong, Jianwen, Park, Soon Young, Nguyen, Nghi, Ezhilarasan, Ravesanker, Martinez-Ledesma, Emmanuel, Wu, Shaofang, Henry, Verlene, Piao, Yuji, Tiao, Ningyi, Brunell, David, Stephan, Clifford, Verhaak, Roel, Sulman, Erik, Balasubramaniyan, Veerakumar, de Groot, John F.
Publicado 2018

A randomized controlled phase III study of VB-111 combined with bevacizumab vs bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE)

por Cloughesy, Timothy F, Brenner, Andrew, de Groot, John F, Butowski, Nicholas A, Zach, Leor, Campian, Jian L, Ellingson, Benjamin M, Freedman, Laurence S, Cohen, Yael C, Lowenton-Spier, Noa, Rachmilewitz Minei, Tamar, Fain Shmueli, Shifra, Wen, Patrick Y
Publicado 2020

Objective response rate targets for recurrent glioblastoma clinical trials based on the historic association between objective response rate and median overall survival

por Ellingson, Benjamin M, Wen, Patrick Y, Chang, Susan M, van den Bent, Martin, Vogelbaum, Michael A, Li, Gang, Li, Shanpeng, Kim, Jiyoon, Youssef, Gilbert, Wick, Wolfgang, Lassman, Andrew B, Gilbert, Mark R, de Groot, John F, Weller, Michael, Galanis, Evanthia, Cloughesy, Timothy F
Publicado 2023

Validation of diffusion MRI as a biomarker for efficacy using randomized phase III trial of bevacizumab with or without VB-111 in recurrent glioblastoma

por Ellingson, Benjamin M, Patel, Kunal, Wang, Chencai, Raymond, Catalina, Brenner, Andrew, de Groot, John F, Butowski, Nicholas A, Zach, Leor, Campian, Jian L, Schlossman, Jacob, Rizvi, Shan, Cohen, Yael C, Lowenton-Spier, Noa, Minei, Tamar Rachmilewitz, Shmueli, Shifra Fain, Wen, Patrick Y, Cloughesy, Timothy F
Publicado 2021

A validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram

por Ferguson, Sherise D, Hodges, Tiffany R, Majd, Nazanin K, Alfaro-Munoz, Kristin, Al-Holou, Wajd N, Suki, Dima, de Groot, John F, Fuller, Gregory N, Xue, Lee, Li, Miao, Jacobs, Carmen, Rao, Ganesh, Colen, Rivka R, Xiu, Joanne, Verhaak, Roel, Spetzler, David, Khasraw, Mustafa, Sawaya, Raymond, Long, James P, Heimberger, Amy B
Publicado 2020

Report of National Brain Tumor Society roundtable workshop on innovating brain tumor clinical trials: building on lessons learned from COVID-19 experience

por Lee, Eudocia Q, Selig, Wendy, Meehan, Clair, Bacha, Jeffrey, Barone, Amy, Bloomquist, Erik, Chang, Susan M, de Groot, John F, Galanis, Evanthia, Hassan, Islam, Kalidas, Chitkala, Khasraw, Mustafa, Kvedar, Joseph C, Lassman, Andrew B, Puduvalli, Vinay, Sahebjam, Solmaz, Schwamm, Lee H, Tamir, Sharon, Welch, Mary, Yung, W K Alfred, Zadeh, Gelareh, Arons, David, Wen, Patrick Y
Publicado 2021