Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols

por Strikwold, Marije, Spenkelink, Bert, de Haan, Laura H. J., Woutersen, Ruud A., Punt, Ans, Rietjens, Ivonne M. C. M.
Publicado 2016

Estrogen receptor alpha (ERα)–mediated coregulator binding and gene expression discriminates the toxic ERα agonist diethylstilbestrol (DES) from the endogenous ERα agonist 17β-estr...

por Adam, Aziza Hussein Bakheit, de Haan, Laura H. J., Estruch, Ignacio Miro, Hooiveld, Guido J. E. J., Louisse, Jochem, Rietjens, Ivonne M. C. M.
Publicado 2020