Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth

por Rovithi, Maria, de Haas, Richard R., Honeywell, Richard J., Poel, Dennis, Peters, Godefridus J., Griffioen, Arjan W., Verheul, Henk M. W.
Publicado 2016

Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib

por Gotink, Kristy J., Rovithi, Maria, de Haas, Richard R., Honeywell, Richard J., Dekker, Henk, Poel, Dennis, Azijli, Kaamar, Peters, Godefridus J., Broxterman, Henk J., Verheul, Henk M. W.
Publicado 2015

Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasc...

por Gotink, Kristy J., Broxterman, Henk J., Honeywell, Richard J., Dekker, Henk, de Haas, Richard R., Miles, Kiersten M., Adelaiye, Remi, Griffioen, Arjan W., Peters, Godefridus J., Pili, Roberto, Verheul, Henk M.W.
Publicado 2014

Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3–Linked Sialic Acid Ligand Binding

por Li, Rui-Jún Eveline, de Haas, Aram, Rodríguez, Ernesto, Kalay, Hakan, Zaal, Anouk, Jimenez, Connie R., Piersma, Sander R., Pham, Thang V., Henneman, Alex A., de Goeij-de Haas, Richard R., van Vliet, Sandra J., van Kooyk, Yvette
Publicado 2021

Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies

por Cordo’, Valentina, Meijer, Mariska T., Hagelaar, Rico, de Goeij-de Haas, Richard R., Poort, Vera M., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Oshima, Koichi, Ferrando, Adolfo A., Zaman, Guido J. R., Jimenez, Connie R., Meijerink, Jules P. P.
Publicado 2022

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

por Beekhof, Robin, van Alphen, Carolien, Henneman, Alex A, Knol, Jaco C, Pham, Thang V, Rolfs, Frank, Labots, Mariette, Henneberry, Evan, Le Large, Tessa YS, de Haas, Richard R, Piersma, Sander R, Vurchio, Valentina, Bertotti, Andrea, Trusolino, Livio, Verheul, Henk MW, Jimenez, Connie R
Publicado 2019

Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

por Zoetemelk, Marloes, Ramzy, George M., Rausch, Magdalena, Koessler, Thibaud, van Beijnum, Judy R., Weiss, Andrea, Mieville, Valentin, Piersma, Sander R., de Haas, Richard R., Delucinge‐Vivier, Céline, Andres, Axel, Toso, Christian, Henneman, Alexander A., Ragusa, Simone, Petrova, Tatiana V., Docquier, Mylène, McKee, Thomas A., Jimenez, Connie R., Daali, Youssef, Griffioen, Arjan W., Rubbia‐Brandt, Laura, Dietrich, Pierre‐Yves, Nowak‐Sliwinska, Patrycja
Publicado 2020

Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

por Buffart, Tineke E., van den Oord, Rosanne A. H. M., van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F. M., van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R., Dekker, Henk, Piersma, Sander R., Pham, Thang V., van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R., Verheul, Henk M. W.
Publicado 2021

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers

por Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Publicado 2022

Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers

por Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Publicado 2022