Value of Organoids from Comparative Epithelia Models

por Schwarz, Julia S., de Jonge, Hugo R., Forrest, John N.
Publicado 2015

Anti-Cancer Auto-Antibodies: Roles, Applications and Open Issues

por de Jonge, Hugo, Iamele, Luisa, Maggi, Maristella, Pessino, Greta, Scotti, Claudia
Publicado 2021

Rescue of Murine F508del CFTR Activity in Native Intestine by Low Temperature and Proteasome Inhibitors

por Wilke, Martina, Bot, Alice, Jorna, Huub, Scholte, Bob J., de Jonge, Hugo R.
Publicado 2012

Strategies for cystic fibrosis transmembrane conductance regulator inhibition: from molecular mechanisms to treatment for secretory diarrhoeas

por de Jonge, Hugo R., Ardelean, Maria C., Bijvelds, Marcel J. C., Vergani, Paola
Publicado 2020

Bicarbonate Transport in Cystic Fibrosis and Pancreatitis

por Angyal, Dora, Bijvelds, Marcel J. C., Bruno, Marco J., Peppelenbosch, Maikel P., de Jonge, Hugo R.
Publicado 2021

Uridine inhibits the stemness of intestinal stem cells in 3D intestinal organoids and mice

por Liu, Yi-Lin, Guo, Song-Ge, Xie, Chun-yan, Niu, Kaimin, De Jonge, Hugo, Wu, Xin
Publicado 2020

Distinguishing Between Monomeric scFv and Diabody in Solution Using Light and Small Angle X-ray Scattering

por Lüdel, Frank, Bufe, Sandra, Bleymüller, Willem M., de Jonge, Hugo, Iamele, Luisa, Niemann, Hartmut H., Hellweg, Thomas
Publicado 2019

Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers

por Yin, Jianyi, Tse, Chung-Ming, Avula, Leela Rani, Singh, Varsha, Foulke-Abel, Jennifer, de Jonge, Hugo R., Donowitz, Mark
Publicado 2018

Spontaneous rescue from cystic fibrosis in a mouse model

por Charizopoulou, Nikoletta, Wilke, Martina, Dorsch, Martina, Bot, Alice, Jorna, Huub, Jansen, Silke, Stanke, Frauke, Hedrich, Hans J, de Jonge, Hugo R, Tümmler, Burkhard
Publicado 2006

Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage

por Ikpa, Pauline T., Sleddens, Hein F. B. M., Steinbrecher, Kris A., Peppelenbosch, Maikel P., de Jonge, Hugo R., Smits, Ron, Bijvelds, Marcel J. C.
Publicado 2016

SMARCA4 inactivating mutations cause concomitant Coffin–Siris syndrome, microphthalmia and small‐cell carcinoma of the ovary hypercalcaemic type

por Errichiello, Edoardo, Mustafa, Noor, Vetro, Annalisa, Notarangelo, Lucia Dora, de Jonge, Hugo, Rinaldi, Berardo, Vergani, Debora, Giglio, Sabrina Rita, Morbini, Patrizia, Zuffardi, Orsetta
Publicado 2017

Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging

por Duranti, Claudia, Carraresi, Laura, Sette, Angelica, Stefanini, Matteo, Lottini, Tiziano, Crescioli, Silvia, Crociani, Olivia, Iamele, Luisa, De Jonge, Hugo, Gherardi, Ermanno, Arcangeli, Annarosa
Publicado 2018

Drug screening identifies gemcitabine inhibiting rotavirus through alteration of pyrimidine nucleotide synthesis pathway

por Chen, Sunrui, Wang, Yining, Li, Pengfei, Yin, Yuebang, Bijvelds, Marcel J., de Jonge, Hugo R., Peppelenbosch, Maikel P., Kainov, Denis E., Pan, Qiuwei
Publicado 2020

Assessing cell-specific effects of genetic variations using tRNA microarrays

por Polte, Christine, Wedemeyer, Daniel, Oliver, Kathryn E., Wagner, Johannes, Bijvelds, Marcel J. C., Mahoney, John, de Jonge, Hugo R., Sorscher, Eric J., Ignatova, Zoya
Publicado 2019

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR

por Bose, Samuel J., Bijvelds, Marcel J. C., Wang, Yiting, Liu, Jia, Cai, Zhiwei, Bot, Alice G. M., de Jonge, Hugo R., Sheppard, David N.
Publicado 2019

LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway

por Spinelli, Sonia, Begani, Giulia, Guida, Lucrezia, Magnone, Mirko, Galante, Denise, D'Arrigo, Cristina, Scotti, Claudia, Iamele, Luisa, De Jonge, Hugo, Zocchi, Elena, Sturla, Laura
Publicado 2021

Cholic Acid Induces a Cftr Dependent Biliary Secretion and Liver Growth Response in Mice

por Bodewes, Frank A. J. A., Bijvelds, Marcel J., de Vries, Willemien, Baller, Juul F. W., Gouw, Annette S. H., de Jonge, Hugo R., Verkade, Henkjan J.
Publicado 2015

Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice

por Ikpa, Pauline T., Doktorova, Marcela, Meijsen, Kelly F., Nieuwenhuijze, Natascha D.A., Verkade, Henkjan J., Jonker, Johan W., de Jonge, Hugo R., Bijvelds, Marcel J.C.
Publicado 2019

Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers

por Ciciriello, Fabiana, Bijvelds, Marcel J. C., Alghisi, Federico, Meijsen, Kelly F., Cristiani, Luca, Sorio, Claudio, Melotti, Paola, Fiocchi, Alessandro G., Lucidi, Vincenzina, De Jonge, Hugo R.
Publicado 2022

A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Im...

por Vallarola, Antonio, Tortarolo, Massimo, De Gioia, Roberta, Iamele, Luisa, de Jonge, Hugo, de Nola, Giovanni, Bovio, Enrica, Pasetto, Laura, Bonetto, Valentina, Freschi, Mattia, Bendotti, Caterina, Gherardi, Ermanno
Publicado 2020