Overview of Biologically Active Nucleoside Phosphonates

por Groaz, Elisabetta, De Jonghe, Steven
Publicado 2021

Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters

por Abdelnabi, Rana, Maes, Piet, de Jonghe, Steven, Weynand, Birgit, Neyts, Johan
Publicado 2022

Influence of 4′-Substitution on the Activity of Gemcitabine and Its ProTide Against VZV and SARS-CoV-2

por Zheng, Zihua, Groaz, Elisabetta, Snoeck, Robert, De Jonghe, Steven, Herdewijn, Piet, Andrei, Graciela
Publicado 2020

Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model

por Abdelnabi, Rana, Foo, Caroline S, De Jonghe, Steven, Maes, Piet, Weynand, Birgit, Neyts, Johan
Publicado 2021

Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model

por Foo, Caroline S., Abdelnabi, Rana, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Weynand, Birgit, Neyts, Johan
Publicado 2022

Exploration of Pyrido[3,4-d]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2

por Van Hoof, Max, Claes, Sandra, Boon, Katrijn, Van Loy, Tom, Schols, Dominique, Dehaen, Wim, De Jonghe, Steven
Publicado 2023

Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists

por Shad, Mastaneh Safarnejad, Claes, Sandra, Goffin, Eline, Van Loy, Tom, Schols, Dominique, De Jonghe, Steven, Dehaen, Wim
Publicado 2021

Discovery of (  ±)-3-(1 H -pyrazol-1-yl)-6,7-dihydro-5 H -[1,2,4]triazolo[3,4- b ][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral activity...

por Jilloju, Parameshwara Chary, Persoons, Leentje, Kurapati, Sathish Kumar, Schols, Dominique, De Jonghe, Steven, Daelemans, Dirk, Vedula, Rajeswar Rao
Publicado 2021

Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket – targeting P-pocket by fragment screening

por Singh, Abhimanyu K., Martinez, Sergio E., Gu, Weijie, Nguyen, Hoai, Schols, Dominique, Herdewijn, Piet, De Jonghe, Steven, Das, Kalyan
Publicado 2021

Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern

por Vangeel, Laura, Chiu, Winston, De Jonghe, Steven, Maes, Piet, Slechten, Bram, Raymenants, Joren, André, Emmanuel, Leyssen, Pieter, Neyts, Johan, Jochmans, Dirk
Publicado 2022

A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection

por Abdelnabi, Rana, Foo, Caroline S., Kaptein, Suzanne J. F., Boudewijns, Robbert, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Weynand, Birgit, Neyts, Johan
Publicado 2022

Substrate-Dependence of Competitive Nucleotide Pyrophosphatase/Phosphodiesterase1 (NPP1) Inhibitors

por Lee, Sang-Yong, Sarkar, Soumya, Bhattarai, Sanjay, Namasivayam, Vigneshwaran, De Jonghe, Steven, Stephan, Holger, Herdewijn, Piet, El-Tayeb, Ali, Müller, Christa E.
Publicado 2017

Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase

por Kasprzyk, Renata, Spiewla, Tomasz J., Smietanski, Miroslaw, Golojuch, Sebastian, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Neyts, Johan, Kowalska, Joanna, Jemielity, Jacek
Publicado 2021

Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model

por Van Loy, Tom, De Jonghe, Steven, Castermans, Karolien, Dheedene, Wouter, Stoop, Reinout, Verschuren, Lars, Versele, Matthias, Chaltin, Patrick, Luttun, Aernout, Schols, Dominique
Publicado 2022

A Set of Experimentally Validated Decoys for the Human CC Chemokine Receptor 7 (CCR7) Obtained by Virtual Screening

por Proj, Matic, De Jonghe, Steven, Van Loy, Tom, Jukič, Marko, Meden, Anže, Ciber, Luka, Podlipnik, Črtomir, Grošelj, Uroš, Konc, Janez, Schols, Dominique, Gobec, Stanislav
Publicado 2022

Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis

por Le, Ngoc-Thao-Hien, De Jonghe, Steven, Erven, Kristien, Vermeyen, Tom, Baldé, Aliou M., Herrebout, Wouter A., Neyts, Johan, Pannecouque, Christophe, Pieters, Luc, Tuenter, Emmy
Publicado 2023

Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore‐based virtual screening approach

por Mirza, Muhammad Usman, Saadabadi, Atefeh, Vanmeert, Michiel, Salo-Ahen, Outi M.H., Abdullah, Iskandar, Claes, Sandra, De Jonghe, Steven, Schols, Dominique, Ahmad, Sarfraz, Froeyen, Matheus
Publicado 2020

Corrigendum to ‘Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore-based virtual screening approach’ [European Journal of Pharmaceutical Sciences...

por Mirza, Muhammad Usman, Saadabadi, Atefeh, Vanmeert, Michiel, Salo-Ahen, Outi M.H., Abdullah, Iskandar, Claes, Sandra, De Jonghe, Steven, Schols, Dominique, Ahmad, Sarfraz, Froeyen, Matheus
Publicado 2021

In vitro activity of itraconazole against SARS‐CoV‐2

por Van Damme, Ellen, De Meyer, Sandra, Bojkova, Denisa, Ciesek, Sandra, Cinatl, Jindrich, De Jonghe, Steven, Jochmans, Dirk, Leyssen, Pieter, Buyck, Christophe, Neyts, Johan, Van Loock, Marnix
Publicado 2021

Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery

por Chiu, Winston, Schepers, Joost, Francken, Thibault, Vangeel, Laura, Abbasi, Kayvan, Jochmans, Dirk, De Jonghe, Steven, Thibaut, Hendrik Jan, Thiel, Volker, Neyts, Johan, Laporte, Manon, Leyssen, Pieter
Publicado 2023