Synthesis and biological evaluation of novel N-α-haloacylated homoserine lactones as quorum sensing modulators

por Syrpas, Michail, Ruysbergh, Ewout, Stevens, Christian V, De Kimpe, Norbert, Mangelinckx, Sven
Publicado 2014

Mechanism of Gram-positive Shock: Identification of Peptidoglycan and Lipoteichoic Acid Moieties Essential in the Induction of Nitric Oxide Synthase, Shock, and Multiple Organ Fail...

por Kengatharan, Ken M., De Kimpe, Sjef, Robson, Caroline, Foster, Simon J., Thiemermann, Christoph
Publicado 1998

Comparison of health conditions treated with traditional and biomedical health care in a Quechua community in rural Bolivia

por Vandebroek, Ina, Thomas, Evert, Sanca, Sabino, Van Damme, Patrick, Puyvelde, Luc Van, De Kimpe, Norbert
Publicado 2008

Disturbed Ca(2+) Homeostasis Increases Glutaminyl Cyclase Expression; Connecting Two Early Pathogenic Events in Alzheimer’s Disease In Vitro

por De Kimpe, Line, Bennis, Anna, Zwart, Rob, van Haastert, Elise S., Hoozemans, Jeroen J. M., Scheper, Wiep
Publicado 2012

Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinam...

por Callebaut, Gert, Mangelinckx, Sven, Van der Veken, Pieter, Törnroos, Karl W, Augustyns, Koen, De Kimpe, Norbert
Publicado 2012

Haloperoxidase Mediated Quorum Quenching by Nitzschia cf pellucida: Study of the Metabolization of N-Acyl Homoserine Lactones by a Benthic Diatom

por Syrpas, Michail, Ruysbergh, Ewout, Blommaert, Lander, Vanelslander, Bart, Sabbe, Koen, Vyverman, Wim, De Kimpe, Norbert, Mangelinckx, Sven
Publicado 2014

Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome

por De Kimpe, Line, van Haastert, Elise S., Kaminari, Archontia, Zwart, Rob, Rutjes, Helma, Hoozemans, Jeroen J. M., Scheper, Wiep
Publicado 2012

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages

por Karimi, Khalil, Sarir, Hadi, Mortaz, Esmaeil, Smit, Joost J, Hosseini, Hossein, De Kimpe, Sjef J, Nijkamp, Frans P, Folkerts, Gert
Publicado 2006

Placebo‐controlled Phase 2 Trial of Drisapersen for Duchenne Muscular Dystrophy

por McDonald, Craig M., Wong, Brenda, Flanigan, Kevin M., Wilson, Rosamund, de Kimpe, Sjef, Lourbakos, Afrodite, Lin, Zhengning, Campion, Giles
Publicado 2018

Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles)

por Bossou, Annick D, Mangelinckx, Sven, Yedomonhan, Hounnankpon, Boko, Pelagie M, Akogbeto, Martin C, De Kimpe, Norbert, Avlessi, Félicien, Sohounhloue, Dominique C K
Publicado 2013

Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3-triazoles and evaluation of their antimalarial activity

por D’hooghe, Matthias, Vandekerckhove, Stéphanie, Mollet, Karen, Vervisch, Karel, Dekeukeleire, Stijn, Lehoucq, Liesbeth, Lategan, Carmen, Smith, Peter J, Chibale, Kelly, De Kimpe, Norbert
Publicado 2011

Long-term Exon Skipping Studies With 2′-O-Methyl Phosphorothioate Antisense Oligonucleotides in Dystrophic Mouse Models

por Tanganyika-de Winter, Christa L, Heemskerk, Hans, Karnaoukh, Tatyana G, van Putten, Maaike, de Kimpe, Sjef J, van Deutekom, Judith, Aartsma-Rus, Annemieke
Publicado 2012

A Sensitive, Reproducible and Objective Immunofluorescence Analysis Method of Dystrophin in Individual Fibers in Samples from Patients with Duchenne Muscular Dystrophy

por Beekman, Chantal, Sipkens, Jessica A., Testerink, Janwillem, Giannakopoulos, Stavros, Kreuger, Dyonne, van Deutekom, Judith C., Campion, Giles V., de Kimpe, Sjef J., Lourbakos, Afrodite
Publicado 2014

Bis(maltolato)oxovanadium(IV) Induces Angiogenesis via Phosphorylation of VEGFR2

por Parma, Laura, Peters, Hendrika A.B., Johansson, Maria E., Gutiérrez, Saray, Meijerink, Henk, de Kimpe, Sjef, de Vries, Margreet R., Quax, Paul H.A.
Publicado 2020

Preclinical Studies on Intestinal Administration of Antisense Oligonucleotides as a Model for Oral Delivery for Treatment of Duchenne Muscular Dystrophy

por van Putten, Maaike, Young, Courtney, van den Berg, Sjoerd, Pronk, Amanda, Hulsker, Margriet, Karnaoukh, Tatyana G, Vermue, Rick, van Dijk, Ko Willems, de Kimpe, Sjef, Aartsma-Rus, Annemieke
Publicado 2014

Long-Term Efficacy, Safety, and Pharmacokinetics of Drisapersen in Duchenne Muscular Dystrophy: Results from an Open-Label Extension Study

por Goemans, Nathalie M., Tulinius, Már, van den Hauwe, Marleen, Kroksmark, Anna-Karin, Buyse, Gunnar, Wilson, Rosamund J., van Deutekom, Judith C., de Kimpe, Sjef J., Lourbakos, Afrodite, Campion, Giles
Publicado 2016

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP)

por Yılmaz-Eliş, A Seda, Aartsma-Rus, Annemieke, ‘t Hoen, Peter AC, Safdar, Huma, Breukel, Cor, van Vlijmen, Bart JM, van Deutekom, Judith, de Kimpe, Sjef, van Ommen, Gert-Jan, Verbeek, J Sjef
Publicado 2013

Preclinical PK and PD Studies on 2′-O-Methyl-phosphorothioate RNA Antisense Oligonucleotides in the mdx Mouse Model

por Heemskerk, Hans, de Winter, Christa, van Kuik, Petra, Heuvelmans, Niki, Sabatelli, Patrizia, Rimessi, Paola, Braghetta, Paola, van Ommen, Gert-Jan B, de Kimpe, Sjef, Ferlini, Alessandra, Aartsma-Rus, Annemieke, van Deutekom, Judith CT
Publicado 2010

The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice

por Verhaart, Ingrid E C, van Vliet-van den Dool, Laura, Sipkens, Jessica A, de Kimpe, Sjef J, Kolfschoten, Ingrid G M, van Deutekom, Judith C T, Liefaard, Lia, Ridings, Jim E, Hood, Steve R, Aartsma-Rus, Annemieke
Publicado 2014

Evaluation of serum MMP-9 as predictive biomarker for antisense therapy in Duchenne

por Lourbakos, A., Yau, N., de Bruijn, P., Hiller, M., Kozaczynska, K., Jean-Baptiste, R., Reza, M., Wolterbeek, R., Koeks, Z., Ayoglu, B., de Klerk, D., Campion, G., Zaharieva, I., Nadarajah, V. D., Nilsson, P., Al-Khalili Szigyarto, C., Muntoni, F., Lochmüller, H., Verschuuren, J. J., Goemans, N., Tulinius, M., Niks, E. H., de Kimpe, S., Aartsma-Rus, A., ’t Hoen, Peter A. C., Spitali, P.
Publicado 2017