Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis

por Babu, Maria, Favretto, Filippo, de Opakua, Alain Ibáñez, Rankovic, Marija, Becker, Stefan, Zweckstetter, Markus
Publicado 2021

Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding

por Sang, Dajun, Shu, Tong, Pantoja, Christian F., de Opakua, Alain Ibáñez, Zweckstetter, Markus, Holt, Liam J.
Publicado 2022

Acetylation discriminates disease-specific tau deposition

por Chakraborty, Pijush, Rivière, Gwladys, Hebestreit, Alina, de Opakua, Alain Ibáñez, Vorberg, Ina M., Andreas, Loren B., Zweckstetter, Markus
Publicado 2023

Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils

por Chakraborty, Pijush, Rivière, Gwladys, Liu, Shu, de Opakua, Alain Ibáñez, Dervişoğlu, Rıza, Hebestreit, Alina, Andreas, Loren B., Vorberg, Ina M., Zweckstetter, Markus
Publicado 2021

The Gαi-GIV binding interface is a druggable protein-protein interaction

por DiGiacomo, Vincent, de Opakua, Alain Ibáñez, Papakonstantinou, Maria P., Nguyen, Lien T., Merino, Nekane, Blanco-Canosa, Juan B., Blanco, Francisco J., Garcia-Marcos, Mikel
Publicado 2017

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

por de Opakua, Alain Ibáñez, Parag-Sharma, Kshitij, DiGiacomo, Vincent, Merino, Nekane, Leyme, Anthony, Marivin, Arthur, Villate, Maider, Nguyen, Lien T., de la Cruz-Morcillo, Miguel Angel, Blanco-Canosa, Juan B., Ramachandran, Sekar, Baillie, George S., Cerione, Richard A., Blanco, Francisco J., Garcia-Marcos, Mikel
Publicado 2017