What are the immunological consequences of long-term use of biological therapies for juvenile idiopathic arthritis?

por Swart, Joost F, de Roock, Sytze, Wulffraat, Nico M
Publicado 2013

High Treg development in the first year of life gives insight into immune regulation

por De Roock, Sytze, Dijkstra, Krijn, Hoeks, Sanne, Prakken, Berent
Publicado 2014

The human microbiome and juvenile idiopathic arthritis

por Verwoerd, Anouk, Ter Haar, Nienke M., de Roock, Sytze, Vastert, Sebastiaan J., Bogaert, Debby
Publicado 2016

Clinical Juvenile Arthritis Disease Activity Score proves to be a useful tool in treat-to-target therapy in juvenile idiopathic arthritis

por Swart, Joost F, van Dijkhuizen, E H Pieter, Wulffraat, Nico M, de Roock, Sytze
Publicado 2018

IL-18 production upon s100 stimulation is reduced in active sJIA patients compared to sJIA patients in remission and healthy controls

por Haar, Nienke Ter, Holzinger, Dirk, de Jager, Wilco, Scholman, Rianne, de Roock, Sytze, Vastert, Bas
Publicado 2014

PD-1/PD-L1 signaling in JIA synovial regulatory T cell function

por de Roock, Sytze, Keustermans, Genoveva, Duurland, Chantal L, Wehrens, Ellen JM, van Wijk, Femke, Prakken, Berent J
Publicado 2011

Serum biomarkers confirming stable remission in inflammatory bowel disease

por Kessel, Christoph, Lavric, Miha, Weinhage, Toni, Brueckner, Markus, de Roock, Sytze, Däbritz, Jan, Weber, Jakob, Vastert, Sebastiaan J., Foell, Dirk
Publicado 2021

A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation

por Wienke, Judith, Janssen, Willemijn, Scholman, Rianne, Spits, Hilde, van Gijn, Marielle, Boes, Marianne, van Montfrans, Joris, Moes, Nicolette, de Roock, Sytze
Publicado 2015

Bone-marrow derived mesenchymal stromal cells infusion in therapy refractory juvenile idiopathic arthritis patients

por Swart, Joost F, de Roock, Sytze, Nievelstein, Rutger A J, Slaper-Cortenbach, Ineke C M, Boelens, Jaap J, Wulffraat, Nico M
Publicado 2019

Monitoring patients with juvenile idiopathic arthritis using health-related quality of life

por Doeleman, Martijn J. H., de Roock, Sytze, Buijsse, Nathan, Klein, Mark, Bonsel, Gouke J., Seyfert-Margolis, Vicki, Swart, Joost F., Wulffraat, Nico M.
Publicado 2021

Methotrexate therapy associated with a reduced rate of new-onset uveitis in patients with biological-naïve juvenile idiopathic arthritis

por van Straalen, Joeri W, Akay, Görkem, Kouwenberg, Carlyn V, de Roock, Sytze, Kalinina Ayuso, Viera, Wulffraat, Nico M, de Boer, Joke, Swart, Joost F
Publicado 2023

Juvenile Arthritis Patients Suffering from Chronic Inflammation Have Increased Activity of Both IDO and GTP-CH1 Pathways But Decreased BH4 Efficacy: Implications for Well-Being, In...

por Korte-Bouws, Gerdien A. H., Albers, Eline, Voskamp, Marije, Hendriksen, Hendrikus, de Leeuw, Lidewij R., Güntürkün, Onur, de Roock, Sytze, Vastert, Sebastiaan J., Korte, S. Mechiel
Publicado 2019

Cord Blood CD4(+) T Cells Respond to Self Heat Shock Protein 60 (HSP60)

por Aalberse, Joost A., Kapitein, Berber, de Roock, Sytze, Klein, Mark R., de Jager, Wilco, van der Zee, Ruurd, Hoekstra, Maarten O., van Wijk, Femke, Prakken, Berent J.
Publicado 2011

Autoimmune disease-associated gene expression is reduced by BET-inhibition

por Peeters, Janneke G.C., Vervoort, Stephin J., Mijnheer, Gerdien, de Roock, Sytze, Vastert, Sebastiaan J., Nieuwenhuis, Edward E.S., van Wijk, Femke, Prakken, Berent J., Mokry, Michal, van Loosdregt, Jorg
Publicado 2015

Prevalence of familial autoimmune diseases in juvenile idiopathic arthritis: results from the international Pharmachild registry

por van Straalen, Joeri W., de Roock, Sytze, Giancane, Gabriella, Alexeeva, Ekaterina, Koskova, Elena, Mesa-del-Castillo Bermejo, Pablo, Zulian, Francesco, Civino, Adele, Montin, Davide, Wulffraat, Nico M., Ruperto, Nicolino, Swart, Joost F.
Publicado 2022

Pharmacological treatment patterns in patients with juvenile idiopathic arthritis in the Netherlands: a real-world data analysis

por Kip, Michelle M A, de Roock, Sytze, Currie, Gillian, Marshall, Deborah A, Grazziotin, Luiza R, Twilt, Marinka, Yeung, Rae S M, Benseler, Susanne M, Vastert, Sebastiaan J, Wulffraat, Nico, Swart, Joost F, IJzerman, Maarten J
Publicado 2022

Juvenile idiopathic arthritis patients with positive family history of autoimmune thyroid disease might benefit from serological screening: analysis of the international Pharmachil...

por van Straalen, Joeri W., Baas, Laurie, Giancane, Gabriella, Grebenkina, Lyudmila, Brunner, Jurgen, Vega-Cornejo, Gabriel, Chasnyk, Vyacheslav G., Harel, Liora, Appenzeller, Simone, Gervais, Elisabeth, de Roock, Sytze, Wulffraat, Nico M., Ruperto, Nicolino, Swart, Joost F.
Publicado 2023

Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity

por Baars, Matthijs J.D., Douma, Thera, Simeonov, Dimitre R., Myers, Darienne R., Kulhanek, Kayla, Banerjee, Saikat, Zwakenberg, Susan, Baltissen, Marijke P., Amini, Mojtaba, de Roock, Sytze, van Wijk, Femke, Vermeulen, Michiel, Marson, Alexander, Roose, Jeroen P., Vercoulen, Yvonne
Publicado 2020

Costs of Hospital‐Associated Care for Patients With Juvenile Idiopathic Arthritis in the Dutch Health Care System

por Kip, Michelle M. A., de Roock, Sytze, van den Berg, Inge, Currie, Gillian, Marshall, Deborah A., Grazziotin, Luiza R., Twilt, Marinka, Yeung, Rae S. M., Benseler, Susanne M., Vastert, Sebastiaan J., Wulffraat, Nico, Swart, Joost F., IJzerman, Maarten J.
Publicado 2022

Real-world comparison of the effects of etanercept and adalimumab on well-being in non-systemic juvenile idiopathic arthritis: a propensity score matched cohort study

por van Straalen, Joeri W., de Roock, Sytze, Giancane, Gabriella, Consolaro, Alessandro, Rygg, Marite, Nordal, Ellen B., Rubio-Pérez, Nadina, Jelusic, Marija, De Inocencio, Jaime, Vojinovic, Jelena, Wulffraat, Nico M., Bruijning-Verhagen, Patricia C. J., Ruperto, Nicolino, Swart, Joost F.
Publicado 2022