The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration

por Fodder, Katherine, de Silva, Rohan, Warner, Thomas T., Bettencourt, Conceição
Publicado 2023

Evolving prion-like tau conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer’s disease tau

por Hromadkova, Lenka, Kim, Chae, Haldiman, Tracy, Peng, Lihua, Zhu, Xiongwei, Cohen, Mark, de Silva, Rohan, Safar, Jiri G.
Publicado 2023

Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson’s disease

por Swirski, Marta, Miners, J Scott, de Silva, Rohan, Lashley, Tammaryn, Ling, Helen, Holton, Janice, Revesz, Tamas, Love, Seth
Publicado 2014

The role of tau in the pathological process and clinical expression of Huntington’s disease

por Vuono, Romina, Winder-Rhodes, Sophie, de Silva, Rohan, Cisbani, Giulia, Drouin-Ouellet, Janelle, Spillantini, Maria G., Cicchetti, Francesca, Barker, Roger A.
Publicado 2015

Association of MAPT haplotype‐tagging polymorphisms with cerebrospinal fluid biomarkers of Alzheimer's disease: A preliminary study in a Croatian cohort

por Babić Leko, Mirjana, Willumsen, Nanet, Nikolac Perković, Matea, Klepac, Nataša, Borovečki, Fran, Hof, Patrick R., Sonicki, Zdenko, Pivac, Nela, de Silva, Rohan, Šimić, Goran
Publicado 2018

A walk through tau therapeutic strategies

por Jadhav, Santosh, Avila, Jesus, Schöll, Michael, Kovacs, Gabor G., Kövari, Enikö, Skrabana, Rostislav, Evans, Lewis D, Kontsekova, Eva, Malawska, Barbara, de Silva, Rohan, Buee, Luc, Zilka, Norbert
Publicado 2019

Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy()

por Cortese, Andrea, Plagnol, Vincent, Brady, Stefen, Simone, Roberto, Lashley, Tammaryn, Acevedo-Arozena, Abraham, de Silva, Rohan, Greensmith, Linda, Holton, Janice, Hanna, Michael G., Fisher, Elizabeth M.C., Fratta, Pietro
Publicado 2014

Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy

por Ferrari, Raffaele, Ryten, Mina, Simone, Roberto, Trabzuni, Daniah, Nicolaou, Naiya, Hondhamuni, Geshanthi, Ramasamy, Adaikalavan, Vandrovcova, Jana, Weale, Michael E., Lees, Andrew J., Momeni, Parastoo, Hardy, John, de Silva, Rohan
Publicado 2014

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

por Šimić, Goran, Babić Leko, Mirjana, Wray, Selina, Harrington, Charles, Delalle, Ivana, Jovanov-Milošević, Nataša, Bažadona, Danira, Buée, Luc, de Silva, Rohan, Di Giovanni, Giuseppe, Wischik, Claude, Hof, Patrick R.
Publicado 2016

Corrigendum to “Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy.” [Neurobiol. Aging 35 (2014...

por Ferrari, Raffaele, Ryten, Mina, Simone, Roberto, Trabzuni, Daniah, Nicolaou, Nayia, Hondhamuni, Geshanthi, Ramasamy, Adaikalavan, Vandrovcova, Jana, Weale, Michael E., Lees, Andrew J., Momeni, Parastoo, Hardy, John, de Silva, Rohan
Publicado 2015

MOBP and HIP1 in multiple system atrophy: New α‐synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis

por Bettencourt, Conceição, Miki, Yasuo, Piras, Ignazio S., de Silva, Rohan, Foti, Sandrine C., Talboom, Joshua S., Revesz, Tamas, Lashley, Tammaryn, Balazs, Robert, Viré, Emmanuelle, Warner, Thomas T., Huentelman, Matt J., Holton, Janice L.
Publicado 2021

A cognitive chameleon: Lessons from a novel MAPT mutation case

por Liang, Yuying, Gordon, Elizabeth, Rohrer, Jonathan, Downey, Laura, de Silva, Rohan, Jäger, Hans Rolf, Nicholas, Jennifer, Modat, Marc, Cardoso, M. Jorge, Mahoney, Colin, Warren, Jason, Rossor, Martin, Fox, Nick, Caine, Diana
Publicado 2014

The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features

por Kara, Eleanna, Ling, Helen, Pittman, Alan M., Shaw, Karen, de Silva, Rohan, Simone, Roberto, Holton, Janice L., Warren, Jason D., Rohrer, Jonathan D., Xiromerisiou, Georgia, Lees, Andrew, Hardy, John, Houlden, Henry, Revesz, Tamas
Publicado 2012

Elevated 4R‐tau in astrocytes from asymptomatic carriers of the MAPT 10+16 intronic mutation

por Setó‐Salvia, Núria, Esteras, Noemi, de Silva, Rohan, de Pablo‐Fernandez, Eduardo, Arber, Charles, Toomey, Christina E., Polke, James M., Morris, Huw R., Rohrer, Jonathan D., Abramov, Andrey Y., Patani, Rickie, Wray, Selina, Warner, Thomas T.
Publicado 2021

Extensive Anti-CoA Immunostaining in Alzheimer’s Disease and Covalent Modification of Tau by a Key Cellular Metabolite Coenzyme A

por Lashley, Tammaryn, Tossounian, Maria-Armineh, Costello Heaven, Neve, Wallworth, Samantha, Peak-Chew, Sew, Bradshaw, Aaron, Cooper, J. Mark, de Silva, Rohan, Srai, Surjit Kaila, Malanchuk, Oksana, Filonenko, Valeriy, Koopman, Margreet B., Rüdiger, Stefan G. D., Skehel, Mark, Gout, Ivan
Publicado 2021

The analysis of C9orf72 repeat expansions in a large series of clinically and pathologically diagnosed cases with atypical parkinsonism()

por Schottlaender, Lucia V., Polke, James M., Ling, Helen, MacDoanld, Nicola D., Tucci, Arianna, Nanji, Tina, Pittman, Alan, de Silva, Rohan, Holton, Janice L., Revesz, Tamas, Sweeney, Mary G., Singleton, Andy B., Lees, Andrew J., Bhatia, Kailash P., Houlden, Henry
Publicado 2015

Erratum to “The analysis of C9orf72 repeat expansions in a large series of clinically and pathologically diagnosed cases with atypical parkinsonism” [Neurobiol. Aging 36 (2015) 122...

por Schottlaender, Lucia V., Polke, James M., Ling, Helen, MacDoanld, Nicola D., Tucci, Arianna, Nanji, Tina, Pittman, Alan, de Silva, Rohan, Holton, Janice L., Revesz, Tamas, Sweeney, Mary G., Singleton, Andy B., Lees, Andrew J., Bhatia, Kailash P., Houlden, Henry
Publicado 2015

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

por Trabzuni, Daniah, Wray, Selina, Vandrovcova, Jana, Ramasamy, Adaikalavan, Walker, Robert, Smith, Colin, Luk, Connie, Gibbs, J. Raphael, Dillman, Allissa, Hernandez, Dena G., Arepalli, Sampath, Singleton, Andrew B., Cookson, Mark R., Pittman, Alan M., de Silva, Rohan, Weale, Michael E., Hardy, John, Ryten, Mina
Publicado 2012

Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice

por Counsell, John R., Karda, Rajvinder, Diaz, Juan Antinao, Carey, Louise, Wiktorowicz, Tatiana, Buckley, Suzanne M.K., Ameri, Shima, Ng, Joanne, Baruteau, Julien, Almeida, Filipa, de Silva, Rohan, Simone, Roberto, Lugarà, Eleonora, Lignani, Gabriele, Lindemann, Dirk, Rethwilm, Axel, Rahim, Ahad A., Waddington, Simon N., Howe, Steven J.
Publicado 2018

Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer’s disease

por Roberts, Malcolm, Sevastou, Ioanna, Imaizumi, Yoichi, Mistry, Kavita, Talma, Sonia, Dey, Madhurima, Gartlon, Jane, Ochiai, Hiroshi, Zhou, Zhi, Akasofu, Shigeru, Tokuhara, Naoki, Ogo, Makoto, Aoyama, Muneo, Aoyagi, Hirofumi, Strand, Kate, Sajedi, Ezat, Agarwala, Kishan Lal, Spidel, Jared, Albone, Earl, Horie, Kanta, Staddon, James M., de Silva, Rohan
Publicado 2020