Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sa...

por Patwardhan, Parag P., Ivy, Kathryn S., Musi, Elgilda, de Stanchina, Elisa, Schwartz, Gary K.
Publicado 2015

Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene

por Kotini, Andriana G, de Stanchina, Elisa, Themeli, Maria, Sadelain, Michel, Papapetrou, Eirini P
Publicado 2016

Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer

por Leftin, Avigdor, Zhao, Huiyong, Turkekul, Mesru, de Stanchina, Elisa, Manova, Katia, Koutcher, Jason A.
Publicado 2017

Establishing and Maintaining an Extensive Library of Patient-Derived Xenograft Models

por Mattar, Marissa, McCarthy, Craig R., Kulick, Amanda R., Qeriqi, Besnik, Guzman, Sean, de Stanchina, Elisa
Publicado 2018

Impact of Combined mTOR and MEK Inhibition in Uveal Melanoma Is Driven by Tumor Genotype

por Ho, Alan L., Musi, Elgilda, Ambrosini, Grazia, Nair, Jayasree S., Deraje Vasudeva, Shyamprasad, de Stanchina, Elisa, Schwartz, Gary K.
Publicado 2012

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

por Poirier, John T., Gardner, Eric E., Connis, Nick, Moreira, Andre L., de Stanchina, Elisa, Hann, Christine L., Rudin, Charles M.
Publicado 2015

Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma

por Portelinha, Ana, da Silva Ferreira, Mariana, Erazo, Tatiana, Jiang, Man, Asgari, Zahra, de Stanchina, Elisa, Younes, Anas, Wendel, Hans-Guido
Publicado 2023

Pazopanib radio-sensitization of human sarcoma tumors

por Wang, Feng, Li, Hongyan, Markovsky, Ela, Glass, Ryan, de Stanchina, Elisa, Powell, Simon N., Schwartz, Gary K., Haimovitz-Friedman, Adriana
Publicado 2018

Anti gC1qR/p32/HABP1 Antibody Therapy Decreases Tumor Growth in an Orthotopic Murine Xenotransplant Model of Triple Negative Breast Cancer

por Peerschke, Ellinor I., de Stanchina, Elisa, Chang, Qing, Manova-Todorova, Katia, Barlas, Afsar, Savitt, Anne G., Geisbrecht, Brian V., Ghebrehiwet, Berhane
Publicado 2020

Analysis of capecitabine metabolites in conjunction with digital autoradiography in a murine model of pancreatic cancer suggests extensive drug penetration through the tumor

por Russell, James, Fanchon, Louise, Alwaseem, Hanan, Molina, Henrik, O’Donoghue, Isabella, Bahr, Amber, de Stanchina, Elisa, Pillarsetty, Nagavarakishore, Humm, John L.
Publicado 2022

Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma

por Mondello, Patrizia, Derenzini, Enrico, Asgari, Zahra, Philip, John, Brea, Elliott J., Seshan, Venkatraman, Hendrickson, Ronald C., de Stanchina, Elisa, Scheinberg, David A., Younes, Anas
Publicado 2017

Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis

por Duan, Shanshan, Moro, Loredana, Qu, Rui, Simoneschi, Daniele, Cho, Hyunwoo, Jiang, Shaowen, Zhao, Huiyong, Chang, Qing, de Stanchina, Elisa, Arbini, Arnaldo A., Pagano, Michele
Publicado 2021

S104: DIFFERENTIAL TARGET PROFILES AND EFFICACY OF ADCLEC.SYN1 AND CD33-CARS IN HUMANIZED AML MODELS

por Haubner, Sascha, Mansilla-Soto, Jorge, Nataraj, Sarah, Kogel, Friederike, Chang, Qing, de Stanchina, Elisa, Lopez, Michael, Fraser, Kathryn, Park, Jae, Wang, Xiuyan, Rivière, Isabelle, Sadelain, Michel
Publicado 2023

Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody

por Lopez-Albaitero, Andres, Xu, Hong, Guo, Hongfen, Wang, Linlin, Wu, Zhihao, Tran, Hoa, Chandarlapaty, Sarat, Scaltriti, Maurizio, Janjigian, Yelena, de Stanchina, Elisa, Cheung, Nai-Kong V.
Publicado 2017

NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death

por Liu, Yuxuan, Mondello, Patrizia, Erazo, Tatiana, Tannan, Neeta Bala, Asgari, Zahra, de Stanchina, Elisa, Nanjangud, Gouri, Seshan, Venkatraman E., Wang, Shenqiu, Wendel, Hans-Guido, Younes, Anas
Publicado 2018

gC1qR/HABP1/p32 Is a Potential New Therapeutic Target Against Mesothelioma

por Peerschke, Ellinor, Stier, Kenneth, Li, Xiaoyu, Kandov, Evelyn, de Stanchina, Elisa, Chang, Qing, Xiong, Yuquan, Manova-Todorova, Katia, Fan, Ning, Barlas, Afsar, Ghebrehiwet, Berhane, Adusumilli, Prasad S.
Publicado 2020

Inhibitory monoclonal antibody targeting ADAM17 expressed on cancer cells

por Saha, Nayanendu, Xu, Kai, Zhu, Zhongyu, Robev, Dorothea, Kalidindi, Teja, Xu, Yan, Himanen, Juha, de Stanchina, Elisa, Pillarsetty, Naga Vara Kishore, Dimitrov, Dimiter S, Nikolov, Dimitar B
Publicado 2021

CIC-Mediated Modulation of MAPK Signaling Opposes Receptor Tyrosine Kinase Inhibitor Response in Kinase-Addicted Sarcoma

por Odintsov, Igor, Ortiz, Michael V., Khodos, Inna, Mattar, Marissa S., Lui, Allan J.W., Kohsaka, Shinji, de Stanchina, Elisa, Bender, Julia L. Glade, Ladanyi, Marc, Somwar, Romel
Publicado 2022

NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy

por Sanghvi, Viraj R., Mohan, Prathibha, Singh, Kamini, Cao, Linlin, Berishaj, Marjan, Wolfe, Andrew L., Schatz, Jonathan H., Lailler, Nathalie, de Stanchina, Elisa, Viale, Agnes, Wendel, Hans-Guido
Publicado 2021

Frequent 4EBP1 Amplification Induces Synthetic Dependence on FGFR Signaling in Cancer

por Mohan, Prathibha, Pasion, Joyce, Ciriello, Giovanni, Lailler, Nathalie, de Stanchina, Elisa, Viale, Agnes, van den Berg, Anke, Diepstra, Arjan, Wendel, Hans-Guido, Sanghvi, Viraj R., Singh, Kamini
Publicado 2022