A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation

por Xu, Huaming, Li, Zhijian, Kuo, Chao-Chung, Götz, Katrin, Look, Thomas, de Toledo, Marcelo AS, Seré, Kristin, Costa, Ivan G, Zenke, Martin
Publicado 2023

Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

por Cypris, Olivia, Frobel, Joana, Rai, Shivam, Franzen, Julia, Sontag, Stephanie, Goetzke, Roman, Szymanski de Toledo, Marcelo A., Zenke, Martin, Wagner, Wolfgang
Publicado 2019

P1365: HUMAN CD117 AS AN IMMUNOTHERAPEUTIC TARGET IN PRECLINICAL MODELS OF ADVANCED SYSTEMIC MASTOCYTOSIS

por Kaiser, Anne, Myburgh, Renier, Volta, Laura, Pellegrino, Christian, Lysenko, Veronika, Theocharides, Alexandre, Brümmendorf, Tim H, de Toledo, Marcelo A.S., Zenke, Martin, Manz, Markus
Publicado 2023

P1008: THE TELOMERASE INHIBITOR IMETELSTAT DIFFERENTIALLY TARGETS JAK2V617F- VERSUS CALR-MUTANT MYELOPROLIFERATIVE NEOPLASM CELLS AND INHIBITS JAK-STAT SIGNALING

por Olschok, Kathrin, Altenburg, Bianca, de Toledo, Marcelo A.S., Maurer, Angela, Abels, Anne, Beier, Fabian, Gezer, Deniz, Isfort, Susanne, Brümmendorf, Tim H, Zenke, Martin, Chatain, Nicolas, Koschmieder, Steffen
Publicado 2023

The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling

por Olschok, Kathrin, Altenburg, Bianca, de Toledo, Marcelo A. S., Maurer, Angela, Abels, Anne, Beier, Fabian, Gezer, Deniz, Isfort, Susanne, Paeschke, Katrin, Brümmendorf, Tim H., Zenke, Martin, Chatain, Nicolas, Koschmieder, Steffen
Publicado 2023

PLA/Hydroxyapatite scaffolds exhibit in vitro immunological inertness and promote robust osteogenic differentiation of human mesenchymal stem cells without osteogenic stimuli

por Bernardo, Marcela P., da Silva, Bruna C. R., Hamouda, Ahmed E. I., de Toledo, Marcelo A. S., Schalla, Carmen, Rütten, Stephan, Goetzke, Roman, Mattoso, Luiz H. C., Zenke, Martin, Sechi, Antonio
Publicado 2022

Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms

por Vieri, Margherita, Tharmapalan, Vithurithra, Kalmer, Milena, Baumeister, Julian, Nikolić, Miloš, Schnitker, Matthis, Kirschner, Martin, Flosdorf, Niclas, de Toledo, Marcelo A. S., Zenke, Martin, Koschmieder, Steffen, Brümmendorf, Tim H., Beier, Fabian, Wagner, Wolfgang
Publicado 2023

KIT D816V Mast Cells Derived from Induced Pluripotent Stem Cells Recapitulate Systemic Mastocytosis Transcriptional Profile

por de Toledo, Marcelo A. S., Fu, Xuhuang, Maié, Tiago, Buhl, Eva M., Götz, Katrin, Schmitz, Susanne, Kaiser, Anne, Boor, Peter, Braunschweig, Till, Chatain, Nicolas, Costa, Ivan G., Brümmendorf, Tim H., Koschmieder, Steffen, Zenke, Martin
Publicado 2023

Analysis of Genomic Regions of Trichoderma harzianum IOC-3844 Related to Biomass Degradation

por Crucello, Aline, Sforça, Danilo Augusto, Horta, Maria Augusta Crivelente, dos Santos, Clelton Aparecido, Viana, Américo José Carvalho, Beloti, Lilian Luzia, de Toledo, Marcelo Augusto Szymanski, Vincentz, Michel, Kuroshu, Reginaldo Massanobu, de Souza, Anete Pereira
Publicado 2015

Early and late stage MPN patients show distinct gene expression profiles in CD34(+) cells

por Baumeister, Julian, Maié, Tiago, Chatain, Nicolas, Gan, Lin, Weinbergerova, Barbora, de Toledo, Marcelo A. S., Eschweiler, Jörg, Maurer, Angela, Mayer, Jiri, Kubesova, Blanka, Racil, Zdenek, Schuppert, Andreas, Costa, Ivan, Koschmieder, Steffen, Brümmendorf, Tim H., Gezer, Deniz
Publicado 2021

GenSeed-HMM: A Tool for Progressive Assembly Using Profile HMMs as Seeds and its Application in Alpavirinae Viral Discovery from Metagenomic Data

por Alves, João M. P., de Oliveira, André L., Sandberg, Tatiana O. M., Moreno-Gallego, Jaime L., de Toledo, Marcelo A. F., de Moura, Elisabeth M. M., Oliveira, Liliane S., Durham, Alan M., Mehnert, Dolores U., Zanotto, Paolo M. de A., Reyes, Alejandro, Gruber, Arthur
Publicado 2016

The Antitoxin Protein of a Toxin-Antitoxin System from Xylella fastidiosa Is Secreted via Outer Membrane Vesicles

por Santiago, André da Silva, Mendes, Juliano S., dos Santos, Clelton A., de Toledo, Marcelo A. S., Beloti, Lilian L., Crucello, Aline, Horta, Maria A. C., Favaro, Marianna T. de Pinho, Munar, Duber M. M., de Souza, Alessandra A., Cotta, Mônica A., de Souza, Anete P.
Publicado 2016

CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes

por Olschok, Kathrin, Han, Lijuan, de Toledo, Marcelo A.S., Böhnke, Janik, Graßhoff, Martin, Costa, Ivan G., Theocharides, Alexandre, Maurer, Angela, Schüler, Herdit M., Buhl, Eva Miriam, Pannen, Kristina, Baumeister, Julian, Kalmer, Milena, Gupta, Siddharth, Boor, Peter, Gezer, Deniz, Brümmendorf, Tim H., Zenke, Martin, Chatain, Nicolas, Koschmieder, Steffen
Publicado 2021