Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

por de Vasconcelos, Nathalia M., Van Opdenbosch, Nina, Van Gorp, Hanne, Parthoens, Eef, Lamkanfi, Mohamed
Publicado 2018

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

por de Vasconcelos, Nathalia M, Vliegen, Gwendolyn, Gonçalves, Amanda, De Hert, Emilie, Martín-Pérez, Rosa, Van Opdenbosch, Nina, Jallapally, Anvesh, Geiss-Friedlander, Ruth, Lambeir, Anne-Marie, Augustyns, Koen, Van Der Veken, Pieter, De Meester, Ingrid, Lamkanfi, Mohamed
Publicado 2019

Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening

por Ioannou, Marianna, Hoving, Dennis, Aramburu, Iker Valle, Temkin, Mia I., De Vasconcelos, Nathalia M., Tsourouktsoglou, Theodora-Dorita, Wang, Qian, Boeing, Stefan, Goldstone, Robert, Vernardis, Spyros, Demichev, Vadim, Ralser, Markus, David, Sascha, Stahl, Klaus, Bode, Christian, Papayannopoulos, Venizelos
Publicado 2022

Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4

por Van Opdenbosch, Nina, Van Gorp, Hanne, Verdonckt, Maarten, Saavedra, Pedro H.V., de Vasconcelos, Nathalia M., Gonçalves, Amanda, Vande Walle, Lieselotte, Demon, Dieter, Matusiak, Magdalena, Van Hauwermeiren, Filip, D’Hont, Jinke, Hochepied, Tino, Krautwald, Stefan, Kanneganti, Thirumala-Devi, Lamkanfi, Mohamed
Publicado 2017

Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia

por Aramburu, Iker Valle, Hoving, Dennis, Vernardis, Spyros I., Tin, Martha C.F., Ioannou, Marianna, Temkin, Mia I., De Vasconcelos, Nathalia M., Demichev, Vadim, Helbig, Elisa Theresa, Lippert, Lena, Stahl, Klaus, White, Matthew, Radbruch, Helena, Ihlow, Jana, Horst, David, Chiesa, Scott T., Deanfield, John E., David, Sascha, Bode, Christian, Kurth, Florian, Ralser, Markus, Papayannopoulos, Venizelos
Publicado 2022