An integrative approach for building personalized gene regulatory networks for precision medicine

por van der Wijst, Monique G. P., de Vries, Dylan H., Brugge, Harm, Westra, Harm-Jan, Franke, Lude
Publicado 2018

Single-cell RNA sequencing identifies cell type-specific cis-eQTLs and co-expression QTLs

por van der Wijst, Monique G.P., Brugge, Harm, de Vries, Dylan H., Deelen, Patrick, Swertz, Morris A., Franke, Lude
Publicado 2018

The necessity of incorporating non-genetic risk factors into polygenic risk score models

por van Dam, Sipko, Folkertsma, Pytrik, Castela Forte, Jose, de Vries, Dylan H., Herrera Cunillera, Camila, Gannamani, Rahul, Wolffenbuttel, Bruce H. R.
Publicado 2023

Lactobacillus reuteri Colonisation of Extremely Preterm Infants in a Randomised Placebo-Controlled Trial

por Spreckels, Johanne E., Wejryd, Erik, Marchini, Giovanna, Jonsson, Baldvin, de Vries, Dylan H., Jenmalm, Maria C., Landberg, Eva, Sverremark-Ekström, Eva, Martí, Magalí, Abrahamsson, Thomas
Publicado 2021

Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response

por de Vries, Dylan H., Matzaraki, Vasiliki, Bakker, Olivier B., Brugge, Harm, Westra, Harm-Jan, Netea, Mihai G., Franke, Lude, Kumar, Vinod, van der Wijst, Monique G. P.
Publicado 2020

Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure

por Oelen, Roy, de Vries, Dylan H., Brugge, Harm, Gordon, M. Grace, Vochteloo, Martijn, Ye, Chun J., Westra, Harm-Jan, Franke, Lude, van der Wijst, Monique G. P.
Publicado 2022

A comparison of myocardial magnetic resonance extracellular volume mapping at 3 T against histology of tissue collagen in severe aortic valve stenosis and obstructive hypertrophic...

por Bakermans, Adrianus J., Kouwenhoven, Merel, de Vos, Judith, de Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., Koolbergen, David R., Kluin, Jolanda, Nederveen, Aart J., Strijkers, Gustav J., Boekholdt, S. Matthijs
Publicado 2023

Effective questionnaire-based prediction models for type 2 diabetes across several ethnicities: a model development and validation study

por Kokkorakis, Michail, Folkertsma, Pytrik, van Dam, Sipko, Sirotin, Nicole, Taheri, Shahrad, Chagoury, Odette, Idaghdour, Youssef, Henning, Robert H., Forte, José Castela, Mantzoros, Christos S., de Vries, Dylan H., Wolffenbuttel, Bruce H.R.
Publicado 2023

shRNAs Targeting a Common KCNQ1 Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele

por Cócera-Ortega, Lucía, Wilders, Ronald, Kamps, Selina C., Fabrizi, Benedetta, Huber, Irit, van der Made, Ingeborg, van den Bout, Anouk, de Vries, Dylan K., Gepstein, Lior, Verkerk, Arie O., Pinto, Yigal M., Tijsen, Anke J.
Publicado 2022

Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

por Li, Shuang, Schmid, Katharina T., de Vries, Dylan H., Korshevniuk, Maryna, Losert, Corinna, Oelen, Roy, van Blokland, Irene V., Groot, Hilde E., Swertz, Morris A., van der Harst, Pim, Westra, Harm-Jan, van der Wijst, Monique G.P., Heinig, Matthias, Franke, Lude
Publicado 2023

Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy

por Bakermans, Adrianus J., Boekholdt, S. Matthijs, de Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., de Heer, Paul, Uthman, Laween, Denis, Simone W., Zuurbier, Coert J., Houtkooper, Riekelt H., Koolbergen, David R., Kluin, Jolanda, Planken, R. Nils, Lamb, Hildo J., Webb, Andrew G., Strijkers, Gustav J., Beard, Daniel A., Jeneson, Jeroen A.L., Nederveen, Aart J.
Publicado 2021

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

por Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique GP, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M., Chu, Xiaojin, Bakker, Olivier B., Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J. P. M., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Franke, Lude, Li, Yang
Publicado 2020

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

por Võsa, Urmo, Claringbould, Annique, Westra, Harm-Jan, Bonder, Marc Jan, Deelen, Patrick, Zeng, Biao, Kirsten, Holger, Saha, Ashis, Kreuzhuber, Roman, Yazar, Seyhan, Brugge, Harm, Oelen, Roy, de Vries, Dylan H., van der Wijst, Monique G.P., Kasela, Silva, Pervjakova, Natalia, Alves, Isabel, Favé, Marie-Julie, Agbessi, Mawussé, Christiansen, Mark W., Jansen, Rick, Seppälä, Ilkka, Tong, Lin, Teumer, Alexander, Schramm, Katharina, Hemani, Gibran, Verlouw, Joost, Yaghootkar, Hanieh, Sönmez, Reyhan, Brown, Andrew, Kukushkina, Viktorija, Kalnapenkis, Anette, Rüeger, Sina, Porcu, Eleonora, Kronberg, Jaanika, Kettunen, Johannes, Lee, Bernett, Zhang, Futao, Qi, Ting, Hernandez, Jose Alquicira, Arindrarto, Wibowo, Beutner, Frank, Dmitrieva, Julia, Elansary, Mahmoud, Fairfax, Benjamin P., Georges, Michel, Heijmans, Bastiaan T., Hewitt, Alex W., Kähönen, Mika, Kim, Yungil, Knight, Julian C., Kovacs, Peter, Krohn, Knut, Li, Shuang, Loeffler, Markus, Marigorta, Urko M., Mei, Hailang, Momozawa, Yukihide, Müller-Nurasyid, Martina, Nauck, Matthias, Nivard, Michel G., Penninx, Brenda WJH., Pritchard, Jonathan K., Raitakari, Olli T., Rotzschke, Olaf, Slagboom, Eline P., Stehouwer, Coen D.A., Stumvoll, Michael, Sullivan, Patrick, ‘t Hoen, Peter A.C., Thiery, Joachim, Tönjes, Anke, van Dongen, Jenny, van Iterson, Maarten, Veldink, Jan H., Völker, Uwe, Warmerdam, Robert, Wijmenga, Cisca, Swertz, Morris, Andiappan, Anand, Montgomery, Grant W., Ripatti, Samuli, Perola, Markus, Kutalik, Zoltan, Dermitzakis, Emmanouil, Bergmann, Sven, Frayling, Timothy, van Meurs, Joyce, Prokisch, Holger, Ahsan, Habibul, Pierce, Brandon L., Lehtimäki, Terho, Boomsma, Dorret I., Psaty, Bruce M., Gharib, Sina A., Awadalla, Philip, Milani, Lili, Ouwehand, Willem H., Downes, Kate, Stegle, Oliver, Battle, Alexis, Visscher, Peter M., Yang, Jian, Scholz, Markus, Powell, Joseph, Gibson, Greg, Esko, Tõnu, Franke, Lude
Publicado 2021