Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70(-/-) mice with human-like bile acids

por de Vries, Hilde D., Palmiotti, Anna, Li, Rumei, Hovingh, Milaine V., Mulder, Niels L., Koehorst, Martijn, Bloks, Vincent W., van Zutphen, Tim, Kuipers, Folkert, de Boer, Jan Freark
Publicado 2022

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition

por Verkade, Esther, Shen, Wenqiang, Hovingh, Milaine V., Mulder, Niels L., de Bruyn, Krisztina, Koehorst, Martijn, de Vries, Hilde D., Bloks, Vincent W., Kuipers, Folkert, de Boer, Jan Freark
Publicado 2023

A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice

por de Boer, Jan Freark, Verkade, Esther, Mulder, Niels L., de Vries, Hilde D., Huijkman, Nicolette, Koehorst, Martijn, Boer, Theo, Wolters, Justina C., Bloks, Vincent W., van de Sluis, Bart, Kuipers, Folkert
Publicado 2020

Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70(−/−) mice by reducing fat absorption

por Li, Rumei, Palmiotti, Anna, de Vries, Hilde D., Hovingh, Milaine V., Koehorst, Martijn, Mulder, Niels L., Zhang, Yue, Kats, Kim, Bloks, Vincent W., Fu, Jingyuan, Verkade, Henkjan J., de Boer, Jan Freark, Kuipers, Folkert
Publicado 2021

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70(−/−) Mice with a Human-like Bile Acid Composition

por Palmiotti, Anna, de Vries, Hilde D., Hovingh, Milaine V., Koehorst, Martijn, Mulder, Niels L., Verkade, Esther, Veentjer, Melany K., van Dijk, Theo H., Bloks, Vincent W., Havinga, Rick, Verkade, Henkjan J., de Boer, Jan Freark, Kuipers, Folkert
Publicado 2023

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

por de Boer, Jan Freark, de Vries, Hilde D., Palmiotti, Anna, Li, Rumei, Doestzada, Marwah, Hoogerland, Joanne A., Fu, Jingyuan, La Rose, Anouk M., Westerterp, Marit, Mulder, Niels L., Hovingh, Milaine V., Koehorst, Martijn, Kloosterhuis, Niels J., Wolters, Justina C., Bloks, Vincent W., Haas, Joel T., Dombrowicz, David, Staels, Bart, van de Sluis, Bart, Kuipers, Folkert
Publicado 2020