The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2

por Bauer, Lisa, Laksono, Brigitta M., de Vrij, Femke M.S., Kushner, Steven A., Harschnitz, Oliver, van Riel, Debby
Publicado 2022

Conserved UBE3A subcellular distribution between human and mice is facilitated by non-homologous isoforms

por Zampeta, F Isabella, Sonzogni, Monica, Niggl, Eva, Lendemeijer, Bas, Smeenk, Hilde, de Vrij, Femke M S, Kushner, Steven A, Distel, Ben, Elgersma, Ype
Publicado 2020

Replication Kinetics, Cell Tropism, and Associated Immune Responses in SARS-CoV-2- and H5N1 Virus-Infected Human Induced Pluripotent Stem Cell-Derived Neural Models

por Bauer, Lisa, Lendemeijer, Bas, Leijten, Lonneke, Embregts, Carmen W. E., Rockx, Barry, Kushner, Steven A., de Vrij, Femke M. S., van Riel, Debby
Publicado 2021

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

por Lindsten, Kristina, de Vrij, Femke M.S., Verhoef, Lisette G.G.C., Fischer, David F., van Leeuwen, Fred W., Hol, Elly M., Masucci, Maria G., Dantuma, Nico P.
Publicado 2002

A simplified protocol for the generation of cortical brain organoids

por Eigenhuis, Kristel N., Somsen, Hedda B., van der Kroeg, Mark, Smeenk, Hilde, Korporaal, Anne L., Kushner, Steven A., de Vrij, Femke M. S., van den Berg, Debbie L. C.
Publicado 2023

An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum

por Higuera, Gustavo A., Iaffaldano, Grazia, Bedar, Meiwand, Shpak, Guy, Broersen, Robin, Munshi, Shashini T., Dupont, Catherine, Gribnau, Joost, de Vrij, Femke M. S., Kushner, Steven A., De Zeeuw, Chris I.
Publicado 2017

In vitro and in vivo differences in neurovirulence between D614G, Delta And Omicron BA.1 SARS-CoV-2 variants

por Bauer, Lisa, Rissmann, Melanie, Benavides, Feline F. W., Leijten, Lonneke, van Run, Peter, Begeman, Lineke, Veldhuis Kroeze, Edwin J. B., Lendemeijer, Bas, Smeenk, Hilde, de Vrij, Femke M. S., Kushner, Steven A., Koopmans, Marion P. G., Rockx, Barry, van Riel, Debby
Publicado 2022

Epigenetic Characterization of the FMR1 Promoter in Induced Pluripotent Stem Cells from Human Fibroblasts Carrying an Unmethylated Full Mutation

por de Esch, Celine E.F., Ghazvini, Mehrnaz, Loos, Friedemann, Schelling-Kazaryan, Nune, Widagdo, W., Munshi, Shashini T., van der Wal, Erik, Douben, Hannie, Gunhanlar, Nilhan, Kushner, Steven A., Pijnappel, W.W.M. Pim, de Vrij, Femke M.S., Geijsen, Niels, Gribnau, Joost, Willemsen, Rob
Publicado 2014

Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells

por Anfasa, Fatih, Siegers, Jurre Y., van der Kroeg, Mark, Mumtaz, Noreen, Stalin Raj, V., de Vrij, Femke M. S., Widagdo, W., Gabriel, Gülsah, Salinas, Sara, Simonin, Yannick, Reusken, Chantal, Kushner, Steven A., Koopmans, Marion P. G., Haagmans, Bart, Martina, Byron E. E., van Riel, Debby
Publicado 2017

ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia

por Bouwkamp, Christian G., Afawi, Zaid, Fattal-Valevski, Aviva, Krabbendam, Inge E., Rivetti, Stefano, Masalha, Rafik, Quadri, Marialuisa, Breedveld, Guido J., Mandel, Hanna, Tailakh, Muhammad Abu, Beverloo, H. Berna, Stevanin, Giovanni, Brice, Alexis, van IJcken, Wilfred F.J., Vernooij, Meike W., Dolga, Amalia M., de Vrij, Femke M.S., Bonifati, Vincenzo, Kushner, Steven A.
Publicado 2018

Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia

por de Vrij, Femke M., Bouwkamp, Christian G., Gunhanlar, Nilhan, Shpak, Guy, Lendemeijer, Bas, Baghdadi, Maarouf, Gopalakrishna, Shreekara, Ghazvini, Mehrnaz, Li, Tracy M., Quadri, Marialuisa, Olgiati, Simone, Breedveld, Guido J., Coesmans, Michiel, Mientjes, Edwin, de Wit, Ton, Verheijen, Frans W., Beverloo, H. Berna, Cohen, Dan, Kok, Rob M., Bakker, P. Roberto, Nijburg, Aviva, Spijker, Annet T., Haffmans, P. M. Judith, Hoencamp, Erik, Bergink, Veerle, Vorstman, Jacob A., Wu, Timothy, Olde Loohuis, Loes M., Amin, Najaf, Langen, Carolyn D., Hofman, Albert, Hoogendijk, Witte J., van Duijn, Cornelia M., Ikram, M. Arfan, Vernooij, Meike W., Tiemeier, Henning, Uitterlinden, André G., Elgersma, Ype, Distel, Ben, Gribnau, Joost, White, Tonya, Bonifati, Vincenzo, Kushner, Steven A.
Publicado 2018