HSPB1 Facilitates the Formation of Non-Centrosomal Microtubules

por Almeida-Souza, Leonardo, Asselbergh, Bob, De Winter, Vicky, Goethals, Sofie, Timmerman, Vincent, Janssens, Sophie
Publicado 2013

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes

por Ydens, Elke, Demon, Dieter, Lornet, Guillaume, De Winter, Vicky, Timmerman, Vincent, Lamkanfi, Mohamed, Janssens, Sophie
Publicado 2015

Charcot–Marie–Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments

por Holmgren, Anne, Bouhy, Delphine, De Winter, Vicky, Asselbergh, Bob, Timmermans, Jean-Pierre, Irobi, Joy, Timmerman, Vincent
Publicado 2013

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies

por Haidar, Mansour, Asselbergh, Bob, Adriaenssens, Elias, De Winter, Vicky, Timmermans, Jean-Pierre, Auer-Grumbach, Michaela, Juneja, Manisha, Timmerman, Vincent
Publicado 2019

Sensory neuropathy-causing mutations in ATL3 affect ER–mitochondria contact sites and impair axonal mitochondrial distribution

por Krols, Michiel, Asselbergh, Bob, De Rycke, Riet, De Winter, Vicky, Seyer, Alexandre, Müller, Franz-Josef, Kurth, Ingo, Bultynck, Geert, Timmerman, Vincent, Janssens, Sophie
Publicado 2019

Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease

por Geuens, Thomas, De Winter, Vicky, Rajan, Nicholas, Achsel, Tilmann, Mateiu, Ligia, Almeida-Souza, Leonardo, Asselbergh, Bob, Bouhy, Delphine, Auer-Grumbach, Michaela, Bagni, Claudia, Timmerman, Vincent
Publicado 2017

Increased Monomerization of Mutant HSPB1 Leads to Protein Hyperactivity in Charcot-Marie-Tooth Neuropathy

por Almeida-Souza, Leonardo, Goethals, Sofie, de Winter, Vicky, Dierick, Ines, Gallardo, Rodrigo, Van Durme, Joost, Irobi, Joy, Gettemans, Jan, Rousseau, Frederic, Schymkowitz, Joost, Timmerman, Vincent, Janssens, Sophie
Publicado 2010

Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space

por Adriaenssens, Elias, Asselbergh, Bob, Rivera-Mejías, Pablo, Bervoets, Sven, Vendredy, Leen, De Winter, Vicky, Spaas, Katrien, de Rycke, Riet, van Isterdael, Gert, Impens, Francis, Langer, Thomas, Timmerman, Vincent
Publicado 2023

Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction

por Van Lent, Jonas, Verstraelen, Peter, Asselbergh, Bob, Adriaenssens, Elias, Mateiu, Ligia, Verbist, Christophe, De Winter, Vicky, Eggermont, Kristel, Van Den Bosch, Ludo, De Vos, Winnok H, Timmerman, Vincent
Publicado 2021

Mutant HSPB8 causes motor neuron-specific neurite degeneration

por Irobi, Joy, Almeida-Souza, Leonardo, Asselbergh, Bob, De Winter, Vicky, Goethals, Sofie, Dierick, Ines, Krishnan, Jyothsna, Timmermans, Jean-Pierre, Robberecht, Wim, De Jonghe, Peter, Van Den Bosch, Ludo, Janssens, Sophie, Timmerman, Vincent
Publicado 2010

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8

por Bouhy, Delphine, Juneja, Manisha, Katona, Istvan, Holmgren, Anne, Asselbergh, Bob, De Winter, Vicky, Hochepied, Tino, Goossens, Steven, Haigh, Jody J., Libert, Claude, Ceuterick-de Groote, Chantal, Irobi, Joy, Weis, Joachim, Timmerman, Vincent
Publicado 2017

Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1

por Capponi, Simona, Geuens, Thomas, Geroldi, Alessandro, Origone, Paola, Verdiani, Simonetta, Cichero, Elena, Adriaenssens, Elias, De Winter, Vicky, Bandettini di Poggio, Monica, Barberis, Marco, Chiò, Adriano, Fossa, Paola, Mandich, Paola, Bellone, Emilia, Timmerman, Vincent
Publicado 2016

NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice

por Jennings, Matthew J, Kagiava, Alexia, Vendredy, Leen, Spaulding, Emily L, Stavrou, Marina, Hathazi, Denisa, Grüneboom, Anika, De Winter, Vicky, Gess, Burkhard, Schara, Ulrike, Pogoryelova, Oksana, Lochmüller, Hanns, Borchers, Christoph H, Roos, Andreas, Burgess, Robert W, Timmerman, Vincent, Kleopa, Kleopas A, Horvath, Rita
Publicado 2022