Childhood Adversity Is Associated With Increased KITLG Methylation in Healthy Individuals but Not in Bipolar Disorder Patients

por He, Yujie, Vinkers, Christiaan H., Houtepen, Lotte C., de Witte, Lot D., Boks, Marco P.
Publicado 2019

The association between antibodies to neurotropic pathogens and schizophrenia: a case-control study

por de Witte, Lot D, van Mierlo, Hans C, Litjens, Manja, Klein, Hans C, Bahn, Sabine, Osterhaus, Ab D
Publicado 2015

Long-term effects of prenatal infection on the human brain: a prospective multimodal neuroimaging study

por Suleri, Anna, Cecil, Charlotte, Rommel, Anna-Sophie, Hillegers, Manon, White, Tonya, de Witte, Lot D., Muetzel, Ryan L., Bergink, Veerle
Publicado 2023

Characterization of macrophages from schizophrenia patients

por Ormel, Paul R., van Mierlo, Hans C., Litjens, Manja, Strien, Miriam E. van, Hol, Elly M., Kahn, René S., de Witte, Lot D.
Publicado 2017

Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression

por Böttcher, Chotima, Fernández-Zapata, Camila, Snijders, Gijsje J. L., Schlickeiser, Stephan, Sneeboer, Marjolein A. M., Kunkel, Desiree, De Witte, Lot D., Priller, Josef
Publicado 2020

Inflammatory monocyte gene signature predicts beneficial within group effect of simvastatin in patients with schizophrenia spectrum disorders in a secondary analysis of a randomize...

por Aichholzer, Mareike, Gangadin, Shiral S., Sommer, Iris E.C., Wijkhuis, Annemarie, de Witte, Lot D., Kahn, René S., Bahn, Sabine, Drexhage, Hemmo A., Schiweck, Carmen
Publicado 2022

DNA methylation changes related to nutritional deprivation: a genome-wide analysis of population and in vitro data

por He, Yujie, de Witte, Lot D., Houtepen, Lotte C., Nispeling, Danny M., Xu, Zhida, Yu, Qiong, Yu, Yaqin, Hol, Elly M., Kahn, René S., Boks, Marco P.
Publicado 2019

Synapse Pathology in Schizophrenia: A Meta-analysis of Postsynaptic Elements in Postmortem Brain Studies

por Berdenis van Berlekom, Amber, Muflihah, Cita H, Snijders, Gijsje J L J, MacGillavry, Harold D, Middeldorp, Jinte, Hol, Elly M, Kahn, René S, de Witte, Lot D
Publicado 2020

The association between antibodies to neurotropic pathogens and bipolar disorder: A study in the Dutch Bipolar (DB) Cohort and meta-analysis

por Snijders, Gijsje J. L. J., van Mierlo, Hans C., Boks, Marco P., Begemann, Marieke J. H., Sutterland, Arjen L., Litjens, Manja, Ophoff, Roel A., Kahn, René S., de Witte, Lot D.
Publicado 2019

Cerebrospinal fluid abnormalities in first- and multi-episode schizophrenia-spectrum disorders: impact of clinical and demographical variables

por Oviedo-Salcedo, Tatiana, Wagner, Elias, Campana, Mattia, Gagsteiger, Anna, Strube, Wolfgang, Eichhorn, Peter, Louiset, Marie-Luise, Luykx, Jurjen, de Witte, Lot D., Kahn, René S., Benros, Michael E., Falkai, Peter, Hasan, Alkomiet
Publicado 2021

Characterization of HIV-1 Infection in Microglia-Containing Human Cerebral Organoids

por Gumbs, Stephanie B. H., Berdenis van Berlekom, Amber, Kübler, Raphael, Schipper, Pauline J., Gharu, Lavina, Boks, Marco P., Ormel, Paul R., Wensing, Annemarie M. J., de Witte, Lot D., Nijhuis, Monique
Publicado 2022

Shock and kill within the CNS: A promising HIV eradication approach?

por Nühn, Marieke M., Gumbs, Stephanie B. H., Buchholtz, Ninée V. E. J., Jannink, Lisanne M., Gharu, Lavina, de Witte, Lot D., Wensing, Annemarie M. J., Lewin, Sharon R., Nijhuis, Monique, Symons, Jori
Publicado 2022

In vivo (R)-[(11)C]PK11195 PET imaging of 18kDa translocator protein in recent onset psychosis

por van der Doef, Thalia F, de Witte, Lot D, Sutterland, Arjen L, Jobse, Ellen, Yaqub, Maqsood, Boellaard, Ronald, de Haan, Lieuwe, Eriksson, Jonas, Lammertsma, Adriaan A, Kahn, René S, van Berckel, Bart N M
Publicado 2016

Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated

por Sneeboer, Marjolein A. M., Snijders, Gijsje J. L. J., Berdowski, Woutje M., Fernández-Andreu, Alba, van Mierlo, Hans C., Berdenis van Berlekom, Amber, Litjens, Manja, Kahn, René S., Hol, Elly M., de Witte, Lot D.
Publicado 2019

Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease

por Guttikonda, Sudha R., Sikkema, Lisa, Tchieu, Jason, Saurat, Nathalie, Walsh, Ryan, Harschnitz, Oliver, Ciceri, Gabriele, Sneeboer, Marjolein, Mazutis, Linas, Setty, Manu, Zumbo, Paul, Betel, Doron, de Witte, Lot D., Pe’er, Dana, Studer, Lorenz
Publicado 2021

A loss of mature microglial markers without immune activation in schizophrenia

por Snijders, Gijsje J. L. J., van Zuiden, Welmoed, Sneeboer, Marjolein A. M., Berdenis van Berlekom, Amber, van der Geest, Astrid T., Schnieder, Tatiana, MacIntyre, Donald J., Hol, Elly M., Kahn, René S., de Witte, Lot D.
Publicado 2021

Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses

por Gumbs, Stephanie B. H., Kübler, Raphael, Gharu, Lavina, Schipper, Pauline J., Borst, Anne L., Snijders, Gijsje J. L. J., Ormel, Paul R., van Berlekom, Amber Berdenis, Wensing, Annemarie M. J., de Witte, Lot D., Nijhuis, Monique
Publicado 2022

Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model

por Berdenis van Berlekom, Amber, Kübler, Raphael, Hoogeboom, Jeske W., Vonk, Daniëlle, Sluijs, Jacqueline A., Pasterkamp, R. Jeroen, Middeldorp, Jinte, Kraneveld, Aletta D., Garssen, Johan, Kahn, René S., Hol, Elly M., de Witte, Lot D., Boks, Marco P.
Publicado 2022

Simvastatin Augmentation for Patients With Early-Phase Schizophrenia-Spectrum Disorders: A Double-Blind, Randomized Placebo-Controlled Trial

por Sommer, Iris E, Gangadin, Shiral S, de Witte, Lot D, Koops, Sanne, van Baal, C, Bahn, Sabine, Drexhage, Hemmo, van Haren, N E M, Veling, Wim, Bruggeman, R, Martens, Peter, Wiersma, Sybren, Veerman, Selene R T, Grootens, Koen P, van Beveren, Nico, Kahn, Rene S, Begemann, Marieke J H
Publicado 2021

Genetic analysis of the human microglia transcriptome across brain regions, aging and disease pathologies

por de Paiva Lopes, Katia, Snijders, Gijsje J. L., Humphrey, Jack, Allan, Amanda, Sneeboer, Marjolein, Navarro, Elisa, Schilder, Brian M., Vialle, Ricardo A., Parks, Madison, Missall, Roy, van Zuiden, Welmoed, Gigase, Frederieke, Kübler, Raphael, van Berlekom, Amber Berdenis, Hicks, Emily M., Bӧttcher, Chotima, Priller, Josef, Kahn, René S., de Witte, Lot D., Raj, Towfique
Publicado 2022