Using Zebrafish as a Disease Model to Study Fibrotic Disease

por Wang, Xixin, Copmans, Daniëlle, de Witte, Peter A. M.
Publicado 2021

Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid

por Wang, Xixin, Giusti, Arianna, Ny, Annelii, de Witte, Peter A.
Publicado 2020

Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage

por Dewaele, Michael, Martinet, Wim, Rubio, Noemí, Verfaillie, Tom, de Witte, Peter A, Piette, Jacques, Agostinis, Patrizia
Publicado 2011

An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies

por Martin, Parthena, Reeder, Thadd, Sourbron, Jo, de Witte, Peter A. M., Gammaitoni, Arnold R., Galer, Bradley S.
Publicado 2021

Comparative Antiseizure Analysis of Diverse Natural Coumarin Derivatives in Zebrafish

por Kozioł, Ewelina, Jóźwiak, Krzysztof, Budzyńska, Barbara, de Witte, Peter A. M., Copmans, Daniëlle, Skalicka-Woźniak, Krystyna
Publicado 2021

Efficacy of Fenfluramine and Norfenfluramine Enantiomers and Various Antiepileptic Drugs in a Zebrafish Model of Dravet Syndrome

por Li, Jing, Nelis, Maxim, Sourbron, Jo, Copmans, Daniëlle, Lagae, Lieven, Cabooter, Deirdre, de Witte, Peter A. M.
Publicado 2021

Evaluation of 14 Organic Solvents and Carriers for Screening Applications in Zebrafish Embryos and Larvae

por Maes, Jan, Verlooy, Lien, Buenafe, Olivia E., de Witte, Peter A. M., Esguerra, Camila V., Crawford, Alexander D.
Publicado 2012

Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis

por Guarin, Marlly, Ny, Annelii, De Croze, Noémie, Maes, Jan, Léonard, Marc, Annaert, Pieter, de Witte, Peter A. M.
Publicado 2021

Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor

por Pardon, Marie, Claes, Pieter, Druwé, Sarah, Martini, Murielle, Siekierska, Aleksandra, Menet, Christel, de Witte, Peter A. M., Copmans, Daniëlle
Publicado 2022

Genetic Renal Diseases: The Emerging Role of Zebrafish Models

por Elmonem, Mohamed A., Berlingerio, Sante Princiero, van den Heuvel, Lambertus P., de Witte, Peter A., Lowe, Martin, Levtchenko, Elena N.
Publicado 2018

Insights from Zebrafish and Mouse Models on the Activity and Safety of Ar-Turmerone as a Potential Drug Candidate for the Treatment of Epilepsy

por Orellana-Paucar, Adriana Monserrath, Afrikanova, Tatiana, Thomas, Joice, Aibuldinov, Yelaman K., Dehaen, Wim, de Witte, Peter A. M., Esguerra, Camila V.
Publicado 2013

Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish

por Partoens, Michèle, De Meulemeester, Ann-Sofie, Giong, Hoi-Khoanh, Pham, Duc-Hung, Lee, Jeong-Soo, de Witte, Peter A., Siekierska, Aleksandra
Publicado 2021

Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine

por Zhang, Yifan, Kecskés, Angéla, Copmans, Daniëlle, Langlois, Mélanie, Crawford, Alexander D., Ceulemans, Berten, Lagae, Lieven, de Witte, Peter A. M., Esguerra, Camila V.
Publicado 2015

Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery

por Zhang, Yifan, Heylen, Lise, Partoens, Michèle, Mills, James D., Kaminski, Rafal M., Godard, Patrice, Gillard, Michel, de Witte, Peter A. M., Siekierska, Aleksandra
Publicado 2022

Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants

por Crawford, Alexander D., Liekens, Sandra, Kamuhabwa, Appolinary R., Maes, Jan, Munck, Sebastian, Busson, Roger, Rozenski, Jef, Esguerra, Camila V., de Witte, Peter A. M.
Publicado 2011

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish

por Zhang, Yifan, Vanmeert, Michiel, Siekierska, Aleksandra, Ny, Annelii, John, Jubi, Callewaert, Geert, Lescrinier, Eveline, Dehaen, Wim, de Witte, Peter A. M., Kaminski, Rafal M.
Publicado 2017

Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs

por Afrikanova, Tatiana, Serruys, Ann-Sophie K., Buenafe, Olivia E. M., Clinckers, Ralph, Smolders, Ilse, de Witte, Peter A. M., Crawford, Alexander D., Esguerra, Camila V.
Publicado 2013

Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites

por Cordero-Maldonado, María Lorena, Siverio-Mota, Dany, Vicet-Muro, Liliana, Wilches-Arizábala, Isabel María, Esguerra, Camila V., de Witte, Peter A. M., Crawford, Alexander D.
Publicado 2013

Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities

por De Meulemeester, Ann-Sofie, Heylen, Lise, Siekierska, Aleksandra, Mills, James D., Romagnolo, Alessia, Van Der Wel, Nicole N., Aronica, Eleonora, de Witte, Peter A. M.
Publicado 2022

Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B

por Copmans, Daniëlle, Kildgaard, Sara, Rasmussen, Silas A., Ślęzak, Monika, Dirkx, Nina, Partoens, Michèle, Esguerra, Camila V., Crawford, Alexander D., Larsen, Thomas O., de Witte, Peter A. M.
Publicado 2019