Prioritization of New Candidate Genes for Rare Genetic Diseases by a Disease-Aware Evaluation of Heterogeneous Molecular Networks

por de la Fuente, Lorena, Del Pozo-Valero, Marta, Perea-Romero, Irene, Blanco-Kelly, Fiona, Fernández-Caballero, Lidia, Cortón, Marta, Ayuso, Carmen, Mínguez, Pablo
Publicado 2023

Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer

por Luque, Melani, Sanz-Álvarez, Marta, Santamaría, Andrea, Zazo, Sandra, Cristóbal, Ion, de la Fuente, Lorena, Mínguez, Pablo, Eroles, Pilar, Rovira, Ana, Albanell, Joan, Madoz-Gúrpide, Juan, Rojo, Federico
Publicado 2021

New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2

por Pérez-Benavente, Beatriz, Fathinajafabadi, Alihamze, de la Fuente, Lorena, Gandía, Carolina, Martínez-Férriz, Arantxa, Pardo-Sánchez, José Miguel, Milián, Lara, Conesa, Ana, Romero, Octavio A., Carretero, Julián, Matthiesen, Rune, Jariel-Encontre, Isabelle, Piechaczyk, Marc, Farràs, Rosa
Publicado 2022

Fine Breakpoint Mapping by Genome Sequencing Reveals the First Large X Inversion Disrupting the NHS Gene in a Patient with Syndromic Cataracts

por Damián, Alejandra, Ionescu, Raluca Oancea, Rodríguez de Alba, Marta, Tamayo, Alejandra, Trujillo-Tiebas, María José, Cotarelo-Pérez, María Carmen, Pérez Rodríguez, Olga, Villaverde, Cristina, de la Fuente, Lorena, Romero, Raquel, Núñez-Moreno, Gonzalo, Mínguez, Pablo, Ayuso, Carmen, Cortón, Marta
Publicado 2021

tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing

por de la Fuente, Lorena, Arzalluz-Luque, Ángeles, Tardáguila, Manuel, del Risco, Héctor, Martí, Cristina, Tarazona, Sonia, Salguero, Pedro, Scott, Raymond, Lerma, Alberto, Alastrue-Agudo, Ana, Bonilla, Pablo, Newman, Jeremy R. B., Kosugi, Shunichi, McIntyre, Lauren M., Moreno-Manzano, Victoria, Conesa, Ana
Publicado 2020

Aggregated Genomic Data as Cohort-Specific Allelic Frequencies can Boost Variants and Genes Prioritization in Non-Solved Cases of Inherited Retinal Dystrophies

por Iancu, Ionut-Florin, Perea-Romero, Irene, Núñez-Moreno, Gonzalo, de la Fuente, Lorena, Romero, Raquel, Ávila-Fernandez, Almudena, Trujillo-Tiebas, María José, Riveiro-Álvarez, Rosa, Almoguera, Berta, Martín-Mérida, Inmaculada, Del Pozo-Valero, Marta, Damián-Verde, Alejandra, Cortón, Marta, Ayuso, Carmen, Minguez, Pablo
Publicado 2022

Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients

por Ogando, Jesús, Tardáguila, Manuel, Díaz-Alderete, Andrea, Usategui, Alicia, Miranda-Ramos, Vanessa, Martínez-Herrera, Dannys Jorge, de la Fuente, Lorena, García-León, María J., Moreno, María C., Escudero, Sara, Cañete, Juan D., Toribio, María L., Cases, Ildefonso, Pascual-Montano, Alberto, Pablos, José Luis, Mañes, Santos
Publicado 2016

SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification

por Tardaguila, Manuel, de la Fuente, Lorena, Marti, Cristina, Pereira, Cécile, Pardo-Palacios, Francisco Jose, del Risco, Hector, Ferrell, Marc, Mellado, Maravillas, Macchietto, Marissa, Verheggen, Kenneth, Edelmann, Mariola, Ezkurdia, Iakes, Vazquez, Jesus, Tress, Michael, Mortazavi, Ali, Martens, Lennart, Rodriguez-Navarro, Susana, Moreno-Manzano, Victoria, Conesa, Ana
Publicado 2018

An evaluation of pipelines for DNA variant detection can guide a reanalysis protocol to increase the diagnostic ratio of genetic diseases

por Romero, Raquel, de la Fuente, Lorena, Del Pozo-Valero, Marta, Riveiro-Álvarez, Rosa, Trujillo-Tiebas, María José, Martín-Mérida, Inmaculada, Ávila-Fernández, Almudena, Iancu, Ionut-Florin, Perea-Romero, Irene, Núñez-Moreno, Gonzalo, Damián, Alejandra, Rodilla, Cristina, Almoguera, Berta, Cortón, Marta, Ayuso, Carmen, Mínguez, Pablo
Publicado 2022

Analysis of Differentially Expressed MicroRNAs in Serum and Lung Tissues from Individuals with Severe Asthma Treated with Oral Glucocorticoids

por Gil-Martínez, Marta, Lorente-Sorolla, Clara, Rodrigo-Muñoz, José M., Lendínez, Miguel Ángel, Núñez-Moreno, Gonzalo, de la Fuente, Lorena, Mínguez, Pablo, Mahíllo-Fernández, Ignacio, Sastre, Joaquín, Valverde-Monge, Marcela, Quirce, Santiago, Caballero, María L., González-Barcala, Francisco J., Arismendi, Ebymar, Bobolea, Irina, Valero, Antonio, Muñoz, Xavier, Cruz, María Jesús, Martínez-Rivera, Carlos, Plaza, Vicente, Olaguibel, José M., del Pozo, Victoria
Publicado 2023

Peripheral T-cell lymphoma: molecular profiling recognizes subclasses and identifies prognostic markers

por Rodríguez, Marta, Alonso-Alonso, Ruth, Tomás-Roca, Laura, Rodríguez-Pinilla, Socorro M., Manso-Alonso, Rebeca, Cereceda, Laura, Borregón, Jennifer, Villaescusa, Teresa, Córdoba, Raúl, Sánchez-Beato, Margarita, Fernández-Miranda, Ismael, Betancor, Isabel, Bárcena, Carmen, García, Juan F., Mollejo, Manuela, García-Cosio, Mónica, Martin-Acosta, Paloma, Climent, Fina, Caballero, Dolores, de la Fuente, Lorena, Mínguez, Pablo, Kessler, Linda, Scholz, Catherine, Gualberto, Antonio, Mondéjar, Rufino, Piris, Miguel A.
Publicado 2021

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

por Martínez-González, Brenda, Soria, María Eugenia, Vázquez-Sirvent, Lucía, Ferrer-Orta, Cristina, Lobo-Vega, Rebeca, Mínguez, Pablo, de la Fuente, Lorena, Llorens, Carlos, Soriano, Beatriz, Ramos, Ricardo, Cortón, Marta, López-Rodríguez, Rosario, García-Crespo, Carlos, Gallego, Isabel, de Ávila, Ana Isabel, Gómez, Jordi, Enjuanes, Luis, Salar-Vidal, Llanos, Esteban, Jaime, Fernandez-Roblas, Ricardo, Gadea, Ignacio, Ayuso, Carmen, Ruíz-Hornillos, Javier, Verdaguer, Nuria, Domingo, Esteban, Perales, Celia
Publicado 2022

SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations

por Martínez-González, Brenda, Soria, María Eugenia, Vázquez-Sirvent, Lucía, Ferrer-Orta, Cristina, Lobo-Vega, Rebeca, Mínguez, Pablo, de la Fuente, Lorena, Llorens, Carlos, Soriano, Beatriz, Ramos-Ruíz, Ricardo, Cortón, Marta, López-Rodríguez, Rosario, García-Crespo, Carlos, Somovilla, Pilar, Durán-Pastor, Antoni, Gallego, Isabel, de Ávila, Ana Isabel, Delgado, Soledad, Morán, Federico, López-Galíndez, Cecilio, Gómez, Jordi, Enjuanes, Luis, Salar-Vidal, Llanos, Esteban-Muñoz, Mario, Esteban, Jaime, Fernández-Roblas, Ricardo, Gadea, Ignacio, Ayuso, Carmen, Ruíz-Hornillos, Javier, Verdaguer, Nuria, Domingo, Esteban, Perales, Celia
Publicado 2022