Emerging roles of DYRK2 in cancer

por Tandon, Vasudha, de la Vega, Laureano, Banerjee, Sourav
Publicado 2021

Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage

por de la Vega, Laureano, Hornung, Juliane, Kremmer, Elisabeth, Milanovic, Maja, Schmitz, M. Lienhard
Publicado 2013

The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner

por Zhang, Ying, Gilmour, Amy, Ahn, Young-Hoon, de la Vega, Laureano, Dinkova-Kostova, Albena T.
Publicado 2021

Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2

por Morrugares, Rosario, Correa-Sáez, Alejandro, Moreno, Rita, Garrido-Rodríguez, Martín, Muñoz, Eduardo, de la Vega, Laureano, Calzado, Marco A.
Publicado 2019

Pirin, an Nrf2-Regulated Protein, Is Overexpressed in Human Colorectal Tumors

por Zhang, Ying, Knatko, Elena V., Higgins, Maureen, Dayalan Naidu, Sharadha, Smith, Gillian, Honda, Tadashi, de la Vega, Laureano, Dinkova-Kostova, Albena T.
Publicado 2022

The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress

por Moreno, Rita, Banerjee, Sourav, Jackson, Angus W., Quinn, Jean, Baillie, Gregg, Dixon, Jack E., Dinkova-Kostova, Albena T., Edwards, Joanne, de la Vega, Laureano
Publicado 2020

Dual inhibition of HSF1 and DYRK2 impedes cancer progression

por Tandon, Vasudha, Moreno, Rita, Allmeroth, Kira, Quinn, Jean, Wiley, Sandra E., Nicely, Lynden G., Denzel, Martin S., Edwards, Joanne, de la Vega, Laureano, Banerjee, Sourav
Publicado 2023

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

por Casares, Laura, García, Víctor, Garrido-Rodríguez, Martín, Millán, Estrella, Collado, Juan A., García-Martín, Adela, Peñarando, Jon, Calzado, Marco A., de la Vega, Laureano, Muñoz, Eduardo
Publicado 2019

Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity

por Casares, Laura, Unciti-Broceta, Juan Diego, Prados, Maria Eugenia, Caprioglio, Diego, Mattoteia, Daiana, Higgins, Maureen, Apendino, Giovanni, Dinkova-Kostova, Albena T., Muñoz, Eduardo, de la Vega, Laureano
Publicado 2020

TRAF6 Phosphorylation Prevents Its Autophagic Degradation and Re-Shapes LPS-Triggered Signaling Networks

por Busch, Julia, Moreno, Rita, de la Vega, Laureano, Saul, Vera Vivian, Bacher, Susanne, von Zweydorf, Felix, Ueffing, Marius, Weber, Axel, Gloeckner, Christian Johannes, Linne, Uwe, Kracht, Michael, Schmitz, Michael Lienhard
Publicado 2021

Downregulation of Keap1 Confers Features of a Fasted Metabolic State

por Knatko, Elena V., Tatham, Michael H., Zhang, Ying, Castro, Cecilia, Higgins, Maureen, Dayalan Naidu, Sharadha, Leonardi, Chiara, de la Vega, Laureano, Honda, Tadashi, Griffin, Julian L., Hay, Ronald T., Dinkova-Kostova, Albena T.
Publicado 2020

High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro

por Torrente, Laura, Maan, Gunjit, Oumkaltoum Rezig, Asma, Quinn, Jean, Jackson, Angus, Grilli, Andrea, Casares, Laura, Zhang, Ying, Kulesskiy, Evgeny, Saarela, Jani, Bicciato, Silvio, Edwards, Joanne, Dinkova-Kostova, Albena T., de la Vega, Laureano
Publicado 2020

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

por Dayalan Naidu, Sharadha, Dikovskaya, Dina, Gaurilcikaite, Egle, Knatko, Elena V., Healy, Zachary R., Mohan, Hema, Koh, Glenn, Laurell, Axel, Ball, Graeme, Olagnier, David, de la Vega, Laureano, Ganley, Ian G., Talalay, Paul, Dinkova-Kostova, Albena T.
Publicado 2017

Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

por Dayalan Naidu, Sharadha, Sutherland, Calum, Zhang, Ying, Risco, Ana, de la Vega, Laureano, Caunt, Christopher J., Hastie, C. James, Lamont, Douglas J., Torrente, Laura, Chowdhry, Sudhir, Benjamin, Ivor J., Keyse, Stephen M., Cuenda, Ana, Dinkova-Kostova, Albena T.
Publicado 2016

A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

por Lara-Chica, Maribel, Correa-Sáez, Alejandro, Jiménez-Izquierdo, Rafael, Garrido-Rodríguez, Martín, Ponce, Francisco J., Moreno, Rita, Morrison, Kimberley, Di Vona, Chiara, Arató, Krisztina, Jiménez-Jiménez, Carla, Morrugares, Rosario, Schmitz, M. Lienhard, de la Luna, Susana, de la Vega, Laureano, Calzado, Marco A.
Publicado 2021

The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity

por Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano
Publicado 2022

Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression

por Banerjee, Sourav, Wei, Tiantian, Wang, Jue, Lee, Jenna J., Gutierrez, Haydee L., Chapman, Owen, Wiley, Sandra E., Mayfield, Joshua E., Tandon, Vasudha, Juarez, Edwin F., Chavez, Lukas, Liang, Ruqi, Sah, Robert L., Costello, Caitlin, Mesirov, Jill P., de la Vega, Laureano, Cooper, Kimberly L., Dixon, Jack E., Xiao, Junyu, Lei, Xiaoguang
Publicado 2019