Deciphering CAD: Structure and function of a mega‐enzymatic pyrimidine factory in health and disease

por del Caño‐Ochoa, Francisco, Ramón‐Maiques, Santiago
Publicado 2021

A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD

por del Caño-Ochoa, Francisco, Rubio-del-Campo, Antonio, Ramón-Maiques, Santiago
Publicado 2023

Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase

por Bellin, Leo, Del Caño-Ochoa, Francisco, Velázquez-Campoy, Adrián, Möhlmann, Torsten, Ramón-Maiques, Santiago
Publicado 2021

Phosphorylation of T897 in the dimerization domain of Gemin5 modulates protein interactions and translation regulation

por Francisco-Velilla, Rosario, Embarc-Buh, Azman, Abellan, Salvador, del Caño-Ochoa, Francisco, Ramón-Maiques, Santiago, Martinez-Salas, Encarnacion
Publicado 2022

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders

por Francisco-Velilla, Rosario, Embarc-Buh, Azman, del Caño-Ochoa, Francisco, Abellan, Salvador, Vilar, Marçal, Alvarez, Sara, Fernandez-Jaen, Alberto, Kour, Sukhleen, Rajan, Deepa S, Pandey, Udai Bhan, Ramón-Maiques, Santiago, Martinez-Salas, Encarnacion
Publicado 2022

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

por Hruschka, Natascha, Kalisz, Mark, Subijana, Maria, Graña-Castro, Osvaldo, Del Cano-Ochoa, Francisco, Brunet, Laia Paré, Chernukhin, Igor, Sagrera, Ana, De Reynies, Aurelien, Kloesch, Bernhard, Chin, Suet-Feung, Burgués, Octavio, Andreu, David, Bermejo, Begoña, Cejalvo, Juan Miguel, Sutton, Joe, Caldas, Carlos, Ramón-Maiques, Santiago, Carroll, Jason S., Prat, Aleix, Real, Francisco X., Martinelli, Paola
Publicado 2020

Cell-based analysis of CAD variants identifies individuals likely to benefit from uridine therapy

por del Caño-Ochoa, Francisco, Ng, Bobby G., Abedalthagafi, Malak, Almannai, Mohammed, Cohn, Ronald D., Costain, Gregory, Elpeleg, Orly, Houlden, Henry, Karimiani, Ehsan Ghayoor, Liu, Pengfei, Manzini, M. Chiara, Maroofian, Reza, Muriello, Michael, Al-Otaibi, Ali, Patel, Hema, Shimon, Edvardson, Sutton, V. Reid, Toosi, Mehran Beiraghi, Wolfe, Lynne A., Rosenfeld, Jill A., Freeze, Hudson H., Ramón-Maiques, Santiago
Publicado 2020