Poxvirus immunotherapies in combination with immune checkpoint inhibitors synergize to eliminate tumors in a mouse tumor model

por Foy, Susan P, Rountree, Ryan B, Mandl, Stefaine J, Cote, Joseph, dela Cruz, Tracy, Gordon, Evan, Trent, Erica, Delcayre, Alain
Publicado 2013

Poxvirus-based active immunotherapy synergizes with immune checkpoint inhibitors to cause tumor regression and extend survival in preclinical models of cancer

por Foy, Susan P, Rountree, Ryan B, Cote, Joseph, dela Cruz, Tracy, Gordon, Evan, Trent, Erica, Franzusoff, Alex, Breitmeyer, James B, Mandl, Stefanie J
Publicado 2014

Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy

por Mandl, Stefanie J, Rountree, Ryan B, dela Cruz, Tracy B, Foy, Susan P, Cote, Joseph J, Gordon, Evan J, Trent, Erica, Delcayre, Alain, Franzusoff, Alex
Publicado 2014

Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice

por Foy, Susan P., Sennino, Barbara, dela Cruz, Tracy, Cote, Joseph J., Gordon, Evan J., Kemp, Felicia, Xavier, Veronica, Franzusoff, Alex, Rountree, Ryan B., Mandl, Stefanie J.
Publicado 2016

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

por Foy, Susan P., Mandl, Stefanie J., dela Cruz, Tracy, Cote, Joseph J., Gordon, Evan J., Trent, Erica, Delcayre, Alain, Breitmeyer, James, Franzusoff, Alex, Rountree, Ryan B.
Publicado 2016

Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism

por Spatola, Bradley N., Lerner, Alana G., Wong, Clifford, dela Cruz, Tracy, Welch, Megan, Fung, Wanchi, Kovalenko, Maria, Losenkova, Karolina, Yegutkin, Gennady G., Beers, Courtney, Corbin, John, Soros, Vanessa B.
Publicado 2020