DUX4 induces a transcriptome more characteristic of a less-differentiated cell state and inhibits myogenesis

por Knopp, Paul, Krom, Yvonne D., Banerji, Christopher R. S., Panamarova, Maryna, Moyle, Louise A., den Hamer, Bianca, van der Maarel, Silvère M., Zammit, Peter S.
Publicado 2016

Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice

por Bouwman, Linde F., den Hamer, Bianca, Verveer, Elwin P., Lerink, Lente J. S., Krom, Yvonne D., van der Maarel, Silvère M., de Greef, Jessica C.
Publicado 2020

USP18 is an essential regulator of muscle cell differentiation and maturation

por Olie, Cyriel Sebastiaan, Pinto-Fernández, Adán, Damianou, Andreas, Vendrell, Iolanda, Mei, Hailiang, den Hamer, Bianca, van der Wal, Erik, de Greef, Jessica C., Raz, Vered, Kessler, Benedikt M.
Publicado 2023

Systemic delivery of a DUX4-targeting antisense oligonucleotide to treat facioscapulohumeral muscular dystrophy

por Bouwman, Linde F., den Hamer, Bianca, van den Heuvel, Anita, Franken, Marnix, Jackson, Michaela, Dwyer, Chrissa A., Tapscott, Stephen J., Rigo, Frank, van der Maarel, Silvère M., de Greef, Jessica C.
Publicado 2021

Highly contractile 3D tissue engineered skeletal muscles from human iPSCs reveal similarities with primary myoblast-derived tissues

por van der Wal, Erik, Iuliano, Alessandro, in ’t Groen, Stijn L.M., Bholasing, Anjali P., Priesmann, Dominik, Sharma, Preeti, den Hamer, Bianca, Saggiomo, Vittorio, Krüger, Marcus, Pijnappel, W.W.M. Pim, de Greef, Jessica C.
Publicado 2023

Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

por Hou, Jun, Aerts, Joachim, den Hamer, Bianca, van IJcken, Wilfred, den Bakker, Michael, Riegman, Peter, van der Leest, Cor, van der Spek, Peter, Foekens, John A., Hoogsteden, Henk C., Grosveld, Frank, Philipsen, Sjaak
Publicado 2010

Intrinsic Epigenetic Regulation of the D4Z4 Macrosatellite Repeat in a Transgenic Mouse Model for FSHD

por Krom, Yvonne D., Thijssen, Peter E., Young, Janet M., den Hamer, Bianca, Balog, Judit, Yao, Zizhen, Maves, Lisa, Snider, Lauren, Knopp, Paul, Zammit, Peter S., Rijkers, Tonnie, van Engelen, Baziel G. M., Padberg, George W., Frants, Rune R., Tawil, Rabi, Tapscott, Stephen J., van der Maarel, Silvère M.
Publicado 2013

SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease

por Tapia del Fierro, Andres, den Hamer, Bianca, Benetti, Natalia, Jansz, Natasha, Chen, Kelan, Beck, Tamara, Vanyai, Hannah, Gurzau, Alexandra D., Daxinger, Lucia, Xue, Shifeng, Ly, Thanh Thao Nguyen, Wanigasuriya, Iromi, Iminitoff, Megan, Breslin, Kelsey, Oey, Harald, Krom, Yvonne D., van der Hoorn, Dinja, Bouwman, Linde F., Johanson, Timothy M., Ritchie, Matthew E., Gouil, Quentin A., Reversade, Bruno, Prin, Fabrice, Mohun, Timothy, van der Maarel, Silvère M., McGlinn, Edwina, Murphy, James M., Keniry, Andrew, de Greef, Jessica C., Blewitt, Marnie E.
Publicado 2023