A massively parallel approach for assessing CRISPR off-targets in vitro

por Huang, Shisheng, Huang, Xingxu
Publicado 2023

Base editors: a powerful tool for generating animal models of human diseases

por Lu, Zongyang, Huang, Xingxu
Publicado 2018

Methods and applications of CRISPR/Cas system for genome editing in stem cells

por Yang, Guang, Huang, Xingxu
Publicado 2019

Next-generation pathogen diagnosis with CRISPR/Cas-based detection methods

por Wang, Xinjie, Shang, Xiaoyun, Huang, Xingxu
Publicado 2020

sgRNAcas9: A Software Package for Designing CRISPR sgRNA and Evaluating Potential Off-Target Cleavage Sites

por Xie, Shengsong, Shen, Bin, Zhang, Chaobao, Huang, Xingxu, Zhang, Yonglian
Publicado 2014

A Convenient Cas9-based Conditional Knockout Strategy for Simultaneously Targeting Multiple Genes in Mouse

por Chen, Jiang, Du, Yinan, He, Xueyan, Huang, Xingxu, Shi, Yun S.
Publicado 2017

Construction and optimization of a base editor based on the MS2 system

por Zhang, Shuzhen, Feng, Songjie, Jiang, Wen, Huang, Xingxu, Chen, Jieping
Publicado 2019

Advances in CRISPR/Cas gene therapy for inborn errors of immunity

por Liu, Xinyi, Li, Guanglei, Liu, Yin, Zhou, Fuling, Huang, Xingxu, Li, Kui
Publicado 2023

Cell Division Mode Change Mediates the Regulation of Cerebellar Granule Neurogenesis Controlled by the Sonic Hedgehog Signaling

por Yang, Rong, Wang, Minglei, Wang, Jia, Huang, Xingxu, Yang, Ru, Gao, Wei-Qiang
Publicado 2015

MOV10L1 Binds RNA G-Quadruplex in a Structure-Specific Manner and Resolves It More Efficiently Than MOV10

por Zhang, Xia, Yu, Lina, Ye, Shasha, Xie, Jie, Huang, Xingxu, Zheng, Ke, Sun, Bo
Publicado 2019

ecRESCUE: a novel ecDHFR-regulated RESCUE system with reduced RNA off-targeting activity

por Wang, Yihan, Li, Guo, Li, Xiangyang, Wang, Yuzhe, Huang, Xingxu, Hu, Xiaoxiang, Gao, Jianen
Publicado 2021

Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing

por Li, Guo, Wang, Yihan, Li, Xiangyang, Wang, Yuzhe, Huang, Xingxu, Gao, Jianen, Hu, Xiaoxiang
Publicado 2021

Rapid and Sensitive Diagnosis of Drug-Resistant FLT3-F691L Mutation by CRISPR Detection

por Liu, Yin, Chen, Yanling, Huang, Shisheng, Ma, Xiaodong, Huang, Xingxu, Wang, Xinjie, Zhou, Fuling
Publicado 2021

Ultrasensitive SARS-CoV-2 diagnosis by CRISPR-based screen-printed carbon electrode

por Wu, Lina, Wang, Xinjie, Wu, Chengyuan, Cao, Xizhong, Tang, Taishan, Huang, He, Huang, Xingxu
Publicado 2022

CRISPR/Cas9-mediated knockout of intracellular molecule SHP-1 enhances tumor-killing ability of CD133-targeted CAR T cells in vitro

por Liu, Ming, Zhang, Linlin, Zhong, Mingtian, Long, Yihao, Yang, Wenhui, Liu, Ting, Huang, Xingxu, Ma, Xiaodong
Publicado 2023

Separase Phosphosite Mutation Leads to Genome Instability and Primordial Germ Cell Depletion during Oogenesis

por Xu, Juan, Wang, Meizhi, Gao, Xinxing, Hu, Bian, Du, Yinan, Zhou, Jiankui, Tian, Xuemei, Huang, Xingxu
Publicado 2011

Heritable Multiplex Genetic Engineering in Rats Using CRISPR/Cas9

por Ma, Yuanwu, Shen, Bin, Zhang, Xu, Lu, Yingdong, Chen, Wei, Ma, Jing, Huang, Xingxu, Zhang, Lianfeng
Publicado 2014

Generation of an Oocyte-Specific Cas9 Transgenic Mouse for Genome Editing

por Zhang, Linlin, Zhou, Jiankui, Han, Jinxiong, Hu, Bian, Hou, Ningning, Shi, Yun, Huang, Xingxu, Lou, Xin
Publicado 2016

Enhancing prime editing efficiency by modified pegRNA with RNA G-quadruplexes

por Li, Xiangyang, Wang, Xin, Sun, Wenjun, Huang, Shisheng, Zhong, Mingtian, Yao, Yuan, Ji, Quanjiang, Huang, Xingxu
Publicado 2022

Engineering an adenine base editor in human embryonic stem cells with minimal DNA and RNA off-target activities

por Zhang, Zhenwu, Tao, Wanyu, Huang, Shisheng, Sun, Wenjun, Wang, Yue, Jiang, Wen, Huang, Xingxu, Lin, Chao-Po
Publicado 2022