CRISPR: A Screener’s Guide

por le Sage, Carlos, Lawo, Steffen, Cross, Benedict C. S.
Publicado 2019

CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing

por Chiang, Ting-Wei Will, le Sage, Carlos, Larrieu, Delphine, Demir, Mukerrem, Jackson, Stephen P.
Publicado 2016

Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites

por Brown, Jessica S., Lukashchuk, Natalia, Sczaniecka-Clift, Matylda, Britton, Sébastien, le Sage, Carlos, Calsou, Patrick, Beli, Petra, Galanty, Yaron, Jackson, Stephen P.
Publicado 2015

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

por Nishi, Ryotaro, Wijnhoven, Paul, le Sage, Carlos, Tjeertes, Jorrit, Galanty, Yaron, Forment, Josep V., Clague, Michael J., Urbé, Sylvie, Jackson, Stephen P
Publicado 2014

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

por le Sage, Carlos, Lawo, Steffen, Panicker, Prince, Scales, Tim M. E., Rahman, Syed Asad, Little, Annette S., McCarthy, Nicola J., Moore, Jonathan D., Cross, Benedict C. S.
Publicado 2017

Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

por Wilting, Saskia M, van Boerdonk, Robert AA, Henken, Florianne E, Meijer, Chris JLM, Diosdado, Begoňa, Meijer, Gerrit A, le Sage, Carlos, Agami, Reuven, Snijders, Peter JF, Steenbergen, Renske DM
Publicado 2010

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

por Léveillé, Nicolas, Elkon, Ran, Davalos, Veronica, Manoharan, Vijayalaxmi, Hollingworth, Dave, Vrielink, Joachim Oude, le Sage, Carlos, Melo, Carlos A., Horlings, Hugo M., Wesseling, Jelle, Ule, Jernej, Esteller, Manel, Ramos, Andres, Agami, Reuven
Publicado 2011

A Flexible, Pooled CRISPR Library for Drug Development Screens

por Blanck, Maximilian, Budnik-Zawilska, Milka B., Lenger, Steven R., McGonigle, John E., Martin, Glynn R.A., le Sage, Carlos, Lawo, Steffen, Pemberton, Helen N., Tiwana, Gaganpreet S., Sorrell, David A., Cross, Benedict C.S.
Publicado 2020

Synthetic lethality between PAXX and XLF in mammalian development

por Balmus, Gabriel, Barros, Ana C., Wijnhoven, Paul W.G., Lescale, Chloé, Hasse, Hélène Lenden, Boroviak, Katharina, le Sage, Carlos, Doe, Brendan, Speak, Anneliese O., Galli, Antonella, Jacobsen, Matt, Deriano, Ludovic, Adams, David J., Blackford, Andrew N., Jackson, Stephen P.
Publicado 2016