Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome

por Schijvens, Anne M., ter Heine, Rob, de Wildt, Saskia N., Schreuder, Michiel F.
Publicado 2018

High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints

por Jansen, Anouk M. E., ter Heine, Rob, Verweij, Paul E., Brüggemann, Roger J. M.
Publicado 2023

Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities

por Keizer, Ron J., ter Heine, Rob, Frymoyer, Adam, Lesko, Lawrence J., Mangat, Ranvir, Goswami, Srijib
Publicado 2018

Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies

por Wasmann, Roeland E., Svensson, Elin M., Schalkwijk, Stein J., Brüggemann, Roger J., ter Heine, Rob
Publicado 2020

Repurposing antifungals: population pharmacokinetics of itraconazole and hydroxy-itraconazole following administration of a nanocrystal formulation

por Jansen, Anouk M E, Ter Heine, Rob, Donnelly, J P, Blijlevens, Nicole, Brüggemann, Roger J M
Publicado 2023

Lactate infusion as therapeutical intervention: a scoping review

por van Gemert, Loes A., de Galan, Bastiaan E., Wevers, Ron A., ter Heine, Rob, Willemsen, Michèl A.
Publicado 2022

Correction to: A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis

por van Beek, Stijn W., ter Heine, Rob, Alffenaar, Jan-Willem C., Magis-Escurra, Cecile, Aarnoutse, Rob E., Svensson, Elin M.
Publicado 2021

A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis

por van Beek, Stijn W., ter Heine, Rob, Alffenaar, Jan-Willem C., Magis-Escurra, Cecile, Aarnoutse, Rob E., Svensson, Elin M.
Publicado 2021

Pharmacokinetics of HIV-Integrase Inhibitors During Pregnancy: Mechanisms, Clinical Implications and Knowledge Gaps

por van der Galiën, Ruben, ter Heine, Rob, Greupink, Rick, Schalkwijk, Stein J., van Herwaarden, Antonius E., Colbers, Angela, Burger, David M.
Publicado 2018

Age, Weight, and CYP2D6 Genotype Are Major Determinants of Primaquine Pharmacokinetics in African Children

por Gonçalves, Bronner P., Pett, Helmi, Tiono, Alfred B., Murry, Daryl, Sirima, Sodiomon B., Niemi, Mikko, Bousema, Teun, Drakeley, Chris, ter Heine, Rob
Publicado 2017

Pharmacokinetically‐guided dosing to improve the efficacy of brigatinib in non‐small cell lung cancer patients

por Koele, Simon E., van Beek, Stijn W., van der Wekken, Anthonie J., Piet, Berber, van den Heuvel, Michel M., ter Heine, Rob
Publicado 2021

Low and Highly Variable Exposure to Prophylactic LMWH Nadroparin in Critically Ill Patients: Back to the Drawing Board for Prophylactic Dosing?

por Diepstraten, Jeroen, van Rongen, Anne, Zijlstra, Marianne P., Kruip, Marieke J. H. A., van der Heiden, Pim L. J., ter Heine, Rob
Publicado 2022

Highly sensitive quantification of pemetrexed in human plasma using UPLC‐MS/MS to support microdosing studies

por van Ewijk‐Beneken Kolmer, Eleonora W. J., Teulen, Marga J. A., Boosman, Rene J., de Rouw, Nikki, Burgers, Jacobus A., ter Heine, Rob
Publicado 2021

The effect of chemotherapy on the exposure–response relation of abiraterone in metastatic castration‐resistant prostate cancer

por Boerrigter, Emmy, Benoist, Guillemette E., Overbeek, Joanneke K., Donders, Rogier, Mehra, Niven, van Oort, Inge M., ter Heine, Rob, van Erp, Nielka P.
Publicado 2021

Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies

por Jansen, Anouk M. E., Mertens, Beatrijs, Spriet, Isabel, Verweij, Paul E., Schouten, Jeroen, Wauters, Joost, Debaveye, Yves, ter Heine, Rob, Brüggemann, Roger J. M.
Publicado 2023

Pharmacokinetic boosting to enable a once-daily reduced dose of tofacitinib in patients with rheumatoid arthritis and psoriatic arthritis (the PRACTICAL study)

por van der Togt, Céleste J.T., Verhoef, Lise M., van den Bemt, Bart J.F., den Broeder, Nathan, ter Heine, Rob, den Broeder, Alfons A.
Publicado 2022

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients

por van Erp, Nielka P., van Herpen, Carla M., de Wit, Djoeke, Willemsen, Annelieke, Burger, David M., Huitema, Alwin D. R., Kapiteijn, Ellen, ter Heine, Rob
Publicado 2016

Model-based assessment of the safety of community interventions with primaquine in sub-Saharan Africa

por van Beek, Stijn W., Svensson, Elin M., Tiono, Alfred B., Okebe, Joseph, D’Alessandro, Umberto, Gonçalves, Bronner P., Bousema, Teun, Drakeley, Chris, ter Heine, Rob
Publicado 2021

Evidence‐based rationale for low dose nivolumab in critically ill patients with sepsis‐induced immunosuppression

por van den Haak, Demy A. C., Otten, Leila‐Sophie, Koenen, Hans J. P. M., Smeets, Ruben L., Piet, Berber, Pickkers, Peter, Kox, Matthijs, ter Heine, Rob
Publicado 2023

Simulation-based suggestions to improve ibuprofen dosing for patent ductus arteriosus in preterm newborns

por Flint, Robert B., ter Heine, Rob, Spaans, Edwin, Burger, David M., de Klerk, Johan C. A., Allegaert, Karel, Knibbe, Catherijne A. J., Simons, Sinno H. P.
Publicado 2018