The role of O-GlcNAcylation in development

por Czajewski, Ignacy, van Aalten, Daan M. F.
Publicado 2023

An efficient and versatile synthesis of GlcNAcstatins—potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1,2-a]pyridine scaffold

por Borodkin, Vladimir S., van Aalten, Daan M.F.
Publicado 2010

Tools for functional dissection of site-specific O-GlcNAcylation

por Gorelik, Andrii, van Aalten, Daan M. F.
Publicado 2020

Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds

por Dorfmueller, Helge C., van Aalten, Daan M.F.
Publicado 2010

O-GlcNAcase: Promiscuous Hexosaminidase or Key Regulator of O-GlcNAc Signaling?

por Alonso, Jana, Schimpl, Marianne, van Aalten, Daan M. F.
Publicado 2014

Effects of hypo-O-GlcNAcylation on Drosophila development

por Mariappa, Daniel, Ferenbach, Andrew T., van Aalten, Daan M. F.
Publicado 2018

A mouse model for functional dissection of TAB1 O-GlcNAcylation

por Authier, Florence, Muha, Villő, van Aalten, Daan M.F.
Publicado 2020

Bioinformatic prediction of putative conveyers of O-GlcNAc transferase intellectual disability

por Mitchell, Conor W., Czajewski, Ignacy, van Aalten, Daan M.F.
Publicado 2022

Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins

por Trapannone, Riccardo, Mariappa, Daniel, Ferenbach, Andrew T., vanAalten, Daan M.F.
Publicado 2016

Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase

por Raimi, Olawale G., Hurtado-Guerrero, Ramon, vanAalten, Daan M.F.
Publicado 2018

Chemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell Death

por Pathak, Shalini, Dorfmueller, Helge C., Borodkin, Vladimir S., van Aalten, Daan M.F.
Publicado 2008

GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation

por Dorfmueller, Helge C., Borodkin, Vladimir S., Schimpl, Marianne, van Aalten, Daan M. F.
Publicado 2009

Human OGA binds substrates in a conserved peptide recognition groove

por Schimpl, Marianne, Schüttelkopf, Alexander W., Borodkin, Vladimir S., van Aalten, Daan M. F.
Publicado 2010

Synergy of Peptide and Sugar in O-GlcNAcase Substrate Recognition

por Schimpl, Marianne, Borodkin, Vladimir S., Gray, Lindsey J., van Aalten, Daan M.F.
Publicado 2012

A Structural and Biochemical Model of Processive Chitin Synthesis

por Dorfmueller, Helge C., Ferenbach, Andrew T., Borodkin, Vladimir S., van Aalten, Daan M. F.
Publicado 2014

A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1

por Chen, Xiping, Raimi, Olawale G., Ferenbach, Andrew T., van Aalten, Daan M.F.
Publicado 2020

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

por Lamb, Daniel, Schüttelkopf, Alexander W., van Aalten, Daan M. F., Brighty, David W.
Publicado 2011

Comparative structural analysis of retroviral fusion proteins identifies regions that modulate membrane fusion: a potential retroviral achilles heal?

por Lamb, Daniel, Schüttelkopf, Alexander W, van Aalten, Daan M F, Brighty, David W
Publicado 2011

Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis

por Striebeck, Alexander, Robinson, David A., Schüttelkopf, Alexander W., van Aalten, Daan M. F.
Publicado 2013

Thio-Linked UDP–Peptide Conjugates as O-GlcNAc Transferase Inhibitors

por Rafie, Karim, Gorelik, Andrii, Trapannone, Riccardo, Borodkin, Vladimir S., van Aalten, Daan M. F.
Publicado 2018