Rat traps: filling the toolbox for manipulating the rat genome

por van Boxtel, Ruben, Cuppen, Edwin
Publicado 2010

Stem cell mutations, associated cancer risk, and consequences for regenerative medicine

por Derks, Lucca L.M., van Boxtel, Ruben
Publicado 2023

The Dynamics of Somatic Mutagenesis During Life in Humans

por Manders, Freek, van Boxtel, Ruben, Middelkamp, Sjors
Publicado 2021

Mutation accumulation in mtDNA of cancers resembles mutagenesis in normal stem cells

por Manders, Freek, van Dinter, Jip, van Boxtel, Ruben
Publicado 2022

MutationalPatterns: comprehensive genome-wide analysis of mutational processes

por Blokzijl, Francis, Janssen, Roel, van Boxtel, Ruben, Cuppen, Edwin
Publicado 2018

The Mutagenic Impact of Environmental Exposures in Human Cells and Cancer: Imprints Through Time

por Rosendahl Huber, Axel, Van Hoeck, Arne, Van Boxtel, Ruben
Publicado 2021

Portrait of a cancer: mutational signature analyses for cancer diagnostics

por Van Hoeck, Arne, Tjoonk, Niels H., van Boxtel, Ruben, Cuppen, Edwin
Publicado 2019

SOX4 Mediates TGF-β-Induced Expression of Mesenchymal Markers during Mammary Cell Epithelial to Mesenchymal Transition

por Vervoort, Stephin J., Lourenço, Ana Rita, van Boxtel, Ruben, Coffer, Paul J.
Publicado 2013

The cellular composition and function of the bone marrow niche after allogeneic hematopoietic cell transplantation

por Peci, Flavia, Dekker, Linde, Pagliaro, Anna, van Boxtel, Ruben, Nierkens, Stefan, Belderbos, Mirjam
Publicado 2022

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals

por van Boxtel, Ruben, Toonen, Pim W, Verheul, Mark, van Roekel, Henk S, Nijman, Isaac J, Guryev, Victor, Cuppen, Edwin
Publicado 2008

Early divergence of mutational processes in human fetal tissues

por Kuijk, Ewart, Blokzijl, Francis, Jager, Myrthe, Besselink, Nicolle, Boymans, Sander, Chuva de Sousa Lopes, Susana M., van Boxtel, Ruben, Cuppen, Edwin
Publicado 2019

Whole-genome sequencing and mutational analysis of human cord-blood derived stem and progenitor cells

por Rosendahl Huber, Axel, van Leeuwen, Anaïs J.C. N., Peci, Flavia, de Kanter, Jurrian K., Bertrums, Eline J.M., van Boxtel, Ruben
Publicado 2022

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

por Govers, Anita M.A.P., Wiggers, Caroline R.M., van Boxtel, Ruben, Mokry, Michal, Nieuwenhuis, Edward E.S., Creyghton, Menno P., Bartels, Marije, Coffer, Paul J.
Publicado 2019

Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis

por Hasaart, Karlijn A. L., Manders, Freek, van der Hoorn, Marie-Louise, Verheul, Mark, Poplonski, Tomasz, Kuijk, Ewart, de Sousa Lopes, Susana M. Chuva, van Boxtel, Ruben
Publicado 2020

Megakaryocyte lineage development is controlled by modulation of protein acetylation

por Bartels, Marije, Govers, Anita, Polak, Roel, Vervoort, Stephin, van Boxtel, Ruben, Pals, Cornelieke, Bierings, Marc, van Solinge, Wouter, Egberts, Toine, Nieuwenhuis, Edward, Mokry, Michal, Coffer, Paul James
Publicado 2018

Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis

por Osorio, Fernando G., Rosendahl Huber, Axel, Oka, Rurika, Verheul, Mark, Patel, Sachin H., Hasaart, Karlijn, de la Fonteijne, Lisanne, Varela, Ignacio, Camargo, Fernando D., van Boxtel, Ruben
Publicado 2018

The mutational impact of culturing human pluripotent and adult stem cells

por Kuijk, Ewart, Jager, Myrthe, van der Roest, Bastiaan, Locati, Mauro D., Van Hoeck, Arne, Korzelius, Jerome, Janssen, Roel, Besselink, Nicolle, Boymans, Sander, van Boxtel, Ruben, Cuppen, Edwin
Publicado 2020

Publisher Correction: The mutational impact of culturing human pluripotent and adult stem cells

por Kuijk, Ewart, Jager, Myrthe, van der Roest, Bastiaan, Locati, Mauro D., Van Hoeck, Arne, Korzelius, Jerome, Janssen, Roel, Besselink, Nicolle, Boymans, Sander, van Boxtel, Ruben, Cuppen, Edwin
Publicado 2020

Mutation Signatures of Pediatric Acute Myeloid Leukemia and Normal Blood Progenitors Associated with Differential Patient Outcomes

por Brandsma, Arianne M., Bertrums, Eline J.M., van Roosmalen, Markus J., Hofman, Damon A., Oka, Rurika, Verheul, Mark, Manders, Freek, Ubels, Joske, Belderbos, Mirjam E., van Boxtel, Ruben
Publicado 2021

MutationalPatterns: the one stop shop for the analysis of mutational processes

por Manders, Freek, Brandsma, Arianne M., de Kanter, Jurrian, Verheul, Mark, Oka, Rurika, van Roosmalen, Markus J., van der Roest, Bastiaan, van Hoeck, Arne, Cuppen, Edwin, van Boxtel, Ruben
Publicado 2022