Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity

por Sundqvist, Anders, ten Dijke, Peter, van Dam, Hans
Publicado 2012

Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination

por Xie, Feng, Zhang, Zhengkui, van Dam, Hans, Zhang, Long, Zhou, Fangfang
Publicado 2014

GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb

por Zhou, Fangfang, Zhang, Long, van Laar, Theo, van Dam, Hans, ten Dijke, Peter
Publicado 2011

A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC

por Eichhorn, Pieter J. A, Creyghton, Menno P, Wilhelmsen, Kevin, van Dam, Hans, Bernards, René
Publicado 2007

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation

por Zhang, Long, Zhou, Fangfang, van Laar, Theo, Zhang, Juan, van Dam, Hans, ten Dijke, Peter
Publicado 2011

The regulation of TGF-β/SMAD signaling by protein deubiquitination

por Zhang, Juan, Zhang, Xiaofei, Xie, Feng, Zhang, Zhengkui, van Dam, Hans, Zhang, Long, Zhou, Fangfang
Publicado 2014

Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models

por Li, Yihao, Drabsch, Yvette, Pujuguet, Philippe, Ren, Jiang, van Laar, Theo, Zhang, Long, van Dam, Hans, Clément-Lacroix, Philippe, ten Dijke, Peter
Publicado 2015

Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression

por Ren, Jiang, Smid, Marcel, Iaria, Josephine, Salvatori, Daniela C. F., van Dam, Hans, Zhu, Hong Jian, Martens, John W. M., ten Dijke, Peter
Publicado 2019

VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation

por Li, Yihao, Cui, Chao, Xie, Feng, Kiełbasa, Szymon, Mei, Hailiang, van Dinther, Maarten, van Dam, Hans, Bauer, Andreas, Zhang, Long, ten Dijke, Peter
Publicado 2019

TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness

por Sundqvist, Anders, Vasilaki, Eleftheria, Voytyuk, Oleksandr, Bai, Yu, Morikawa, Masato, Moustakas, Aristidis, Miyazono, Kohei, Heldin, Carl-Henrik, ten Dijke, Peter, van Dam, Hans
Publicado 2020

JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion

por Sundqvist, Anders, Morikawa, Masato, Ren, Jiang, Vasilaki, Eleftheria, Kawasaki, Natsumi, Kobayashi, Mai, Koinuma, Daizo, Aburatani, Hiroyuki, Miyazono, Kohei, Heldin, Carl-Henrik, van Dam, Hans, ten Dijke, Peter
Publicado 2018

JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses

por Sundqvist, Anders, Voytyuk, Oleksandr, Hamdi, Mohamed, Popeijus, Herman E., Bijlsma-van der Burgt, Corina, Janssen, Josephine, Martens, John W.M., Moustakas, Aristidis, Heldin, Carl-Henrik, ten Dijke, Peter, van Dam, Hans
Publicado 2019

Genome-wide assessment of differential roles for p300 and CBP in transcription regulation

por Ramos, Yolande F. M., Hestand, Matthew S., Verlaan, Matty, Krabbendam, Elise, Ariyurek, Yavuz, van Galen, Michiel, van Dam, Hans, van Ommen, Gert-Jan B., den Dunnen, Johan T., Zantema, Alt, ′t Hoen, Peter A. C.
Publicado 2010

Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

por Sánchez‐Duffhues, Gonzalo, García de Vinuesa, Amaya, van de Pol, Vera, Geerts, Marlieke E, de Vries, Margreet R, Janson, Stef GT, van Dam, Hans, Lindeman, Jan H., Goumans, Marie‐José, ten Dijke, Peter
Publicado 2019

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis

por Xie, Feng, Jin, Ke, Shao, Li, Fan, Yao, Tu, Yifei, Li, Yihao, Yang, Bin, van Dam, Hans, ten Dijke, Peter, Weng, Honglei, Dooley, Steven, Wang, Shuai, Jia, Junling, Jin, Jin, Zhou, Fangfang, Zhang, Long
Publicado 2017

BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression

por Naber, Hildegonda P. H., Wiercinska, Eliza, Pardali, Evangelia, van Laar, Theo, Nirmala, Ella, Sundqvist, Anders, van Dam, Hans, van der Horst, Geertje, van der Pluijm, Gabri, Heckmann, Bertrand, Danen, Erik H. J., ten Dijke, Peter
Publicado 2011

Breast cancer cell-derived extracellular vesicles promote CD8(+) T cell exhaustion via TGF-β type II receptor signaling

por Xie, Feng, Zhou, Xiaoxue, Su, Peng, Li, Heyu, Tu, Yifei, Du, Jinjin, Pan, Chen, Wei, Xiang, Zheng, Min, Jin, Ke, Miao, Liyan, Wang, Chao, Meng, Xuli, van Dam, Hans, ten Dijke, Peter, Zhang, Long, Zhou, Fangfang
Publicado 2022

Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7

por Zhang, Zhengkui, Fan, Yao, Xie, Feng, Zhou, Hang, Jin, Ke, Shao, Li, Shi, Wenhao, Fang, Pengfei, Yang, Bing, van Dam, Hans, ten Dijke, Peter, Zheng, Xiaofeng, Yan, Xiaohua, Jia, Junling, Zheng, Min, Jin, Jin, Ding, Chen, Ye, Sheng, Zhou, Fangfang, Zhang, Long
Publicado 2017

Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2

por Gan, Jin, de Vries, Jelle, Akkermans, Jimmy J. L. L., Mohammed, Yassene, Tjokrodirijo, Rayman T. N., de Ru, Arnoud H., Kim, Robbert Q., Vargas, David A., Pol, Vito, Fasan, Rudi, van Veelen, Peter A., Neefjes, Jacques, van Dam, Hans, Ovaa, Huib, Sapmaz, Aysegul, Geurink, Paul P.
Publicado 2023