A fine scale phenotype–genotype virulence map of a bacterial pathogen

por van Opijnen, Tim, Camilli, Andrew
Publicado 2012

ShinyOmics: collaborative exploration of omics-data

por Surujon, Defne, van Opijnen, Tim
Publicado 2020

Strain Dependent Genetic Networks for Antibiotic-Sensitivity in a Bacterial Pathogen with a Large Pan-Genome

por van Opijnen, Tim, Dedrick, Sandra, Bento, José
Publicado 2016

Tn-seq; high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

por van Opijnen, Tim, Bodi, Kip L., Camilli, Andrew
Publicado 2009

Genome-wide phage susceptibility analysis in Acinetobacter baumannii reveals capsule modulation strategies that determine phage infectivity

por Bai, Jinna, Raustad, Nicole, Denoncourt, Jason, van Opijnen, Tim, Geisinger, Edward
Publicado 2023

Adaptation of HIV-1 Depends on the Host-Cell Environment

por van Opijnen, Tim, de Ronde, Anthony, Boerlijst, Maarten C., Berkhout, Ben
Publicado 2007

A decade of advances in transposon-insertion sequencing

por Cain, Amy K., Barquist, Lars, Goodman, Andrew L., Paulsen, Ian T., Parkhill, Julian, van Opijnen, Tim
Publicado 2020

LptD depletion disrupts morphological homeostasis and upregulates carbohydrate metabolism in Escherichia coli

por Frisinger, Frida Svanberg, Jana, Bimal, Ortiz-Marquez, Juan C, van Opijnen, Tim, Donadio, Stefano, Guardabassi, Luca
Publicado 2023

Topologically correct synthetic reconstruction of pathogen social behavior found during Yersinia growth in deep tissue sites

por Clark, Stacie A, Thibault, Derek, Shull, Lauren M, Davis, Kimberly M, Aunins, Emily, van Opijnen, Tim, Isberg, Ralph
Publicado 2020

Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity

por Zhu, Zeyu, Surujon, Defne, Ortiz-Marquez, Juan C., Huo, Wenwen, Isberg, Ralph R., Bento, José, van Opijnen, Tim
Publicado 2020

The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence

por Warrier, Indu, Ram-Mohan, Nikhil, Zhu, Zeyu, Hazery, Ariana, Echlin, Haley, Rosch, Jason, Meyer, Michelle M., van Opijnen, Tim
Publicado 2018

Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes

por Thibault, Derek, Jensen, Paul A., Wood, Stephen, Qabar, Christine, Clark, Stacie, Shainheit, Mara G., Isberg, Ralph R., van Opijnen, Tim
Publicado 2019

Interspecies recombination, not de novo mutation, maintains virulence after β-lactam resistance acquisition in Streptococcus pneumoniae

por Nishimoto, Andrew T., Dao, Tina H., Jia, Qidong, Ortiz-Marquez, Juan C., Echlin, Haley, Vogel, Peter, van Opijnen, Tim, Rosch, Jason W.
Publicado 2022

A bacterial pan-genome makes gene essentiality strain-dependent and evolvable

por Rosconi, Federico, Rudmann, Emily, Li, Jien, Surujon, Defne, Anthony, Jon, Frank, Matthew, Jones, Dakota S., Rock, Charles, Rosch, Jason W., Johnston, Christopher D., van Opijnen, Tim
Publicado 2022

Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice

por Huo, Wenwen, Busch, Lindsay M., Hernandez-Bird, Juan, Hamami, Efrat, Marshall, Christopher W., Geisinger, Edward, Cooper, Vaughn S., van Opijnen, Tim, Rosch, Jason W., Isberg, Ralph R.
Publicado 2022

Control of Virulence by Small RNAs in Streptococcus pneumoniae

por Mann, Beth, van Opijnen, Tim, Wang, Jianmin, Obert, Caroline, Wang, Yong-Dong, Carter, Robert, McGoldrick, Daniel J., Ridout, Granger, Camilli, Andrew, Tuomanen, Elaine I., Rosch, Jason W.
Publicado 2012

The Landscape of Phenotypic and Transcriptional Responses to Ciprofloxacin in Acinetobacter baumannii: Acquired Resistance Alleles Modulate Drug-Induced SOS Response and Prophage R...

por Geisinger, Edward, Vargas-Cuebas, Germán, Mortman, Nadav J., Syal, Sapna, Dai, Yunfei, Wainwright, Elizabeth L., Lazinski, David, Wood, Stephen, Zhu, Zeyu, Anthony, Jon, van Opijnen, Tim, Isberg, Ralph R.
Publicado 2019

Yersinia pseudotuberculosis doxycycline tolerance strategies include modulating expression of genes involved in cell permeability and tRNA modifications

por Alvarez-Manzo, Hector S., Davidson, Robert K., Van Cauwelaert de Wyels, Jasper, Cotten, Katherine L., Nguyen, Benjamin H., Xiao, Melody, Zhu, Zeyu, Anthony, Jon, van Opijnen, Tim, Davis, Kimberly Michele
Publicado 2022

The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter

por Hooppaw, Anna J., McGuffey, Jenna C., Di Venanzio, Gisela, Ortiz-Marquez, Juan C., Weber, Brent S., Lightly, Tasia Joy, van Opijnen, Tim, Scott, Nichollas E., Cardona, Silvia T., Feldman, Mario F.
Publicado 2022

Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

por Geisinger, Edward, Mortman, Nadav J., Dai, Yunfei, Cokol, Murat, Syal, Sapna, Farinha, Andrew, Fisher, Delaney G., Tang, Amy Y., Lazinski, David W., Wood, Stephen, Anthony, Jon, van Opijnen, Tim, Isberg, Ralph R.
Publicado 2020