Patterns and Mechanisms of Ancestral Histone Protein Inheritance in Budding Yeast

por Radman-Livaja, Marta, Verzijlbergen, Kitty F., Weiner, Assaf, van Welsem, Tibor, Friedman, Nir, Rando, Oliver J., van Leeuwen, Fred
Publicado 2011

DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro

por Kwesi-Maliepaard, Eliza Mari, Malik, Muddassir, van Welsem, Tibor, van Doorn, Remco, Vermeer, Maarten H., Vlaming, Hanneke, Jacobs, Heinz, van Leeuwen, Fred
Publicado 2022

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

por Huseinovic, Angelina, van Leeuwen, Jolanda S., van Welsem, Tibor, Stulemeijer, Iris, van Leeuwen, Fred, Vermeulen, Nico P. E., Kooter, Jan M., Vos, J. Chris
Publicado 2017

Decoding the chromatin proteome of a single genomic locus by DNA sequencing

por Korthout, Tessy, Poramba-Liyanage, Deepani W., van Kruijsbergen, Ila, Verzijlbergen, Kitty F., van Gemert, Frank P. A., van Welsem, Tibor, van Leeuwen, Fred
Publicado 2018

A Barcode Screen for Epigenetic Regulators Reveals a Role for the NuB4/HAT-B Histone Acetyltransferase Complex in Histone Turnover

por Verzijlbergen, Kitty F., van Welsem, Tibor, Sie, Daoud, Lenstra, Tineke L., Turner, Daniel J., Holstege, Frank C. P., Kerkhoven, Ron M., van Leeuwen, Fred
Publicado 2011

Recombination-Induced Tag Exchange (RITE) Cassette Series to Monitor Protein Dynamics in Saccharomyces cerevisiae

por Terweij, Marit, van Welsem, Tibor, van Deventer, Sjoerd, Verzijlbergen, Kitty F., Menendez-Benito, Victoria, Ontoso, David, San-Segundo, Pedro, Neefjes, Jacques, van Leeuwen, Fred
Publicado 2013

Inhibition of transcription leads to rewiring of locus-specific chromatin proteomes

por Poramba-Liyanage, Deepani W., Korthout, Tessy, Cucinotta, Christine E., van Kruijsbergen, Ila, van Welsem, Tibor, El Atmioui, Dris, Ovaa, Huib, Tsukiyama, Toshio, van Leeuwen, Fred
Publicado 2020

A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae

por Ming Sun, Su, Batté, Amandine, Elmer, Mireille, van der Horst, Sophie C., van Welsem, Tibor, Bean, Gordon, Ideker, Trey, van Leeuwen, Fred, van Attikum, Haico
Publicado 2020

Strategy for Development of Site-Specific Ubiquitin Antibodies

por van Kruijsbergen, Ila, Mulder, Monique P. C., Uckelmann, Michael, van Welsem, Tibor, de Widt, John, Spanjaard, Aldo, Jacobs, Heinz, El Oualid, Farid, Ovaa, Huib, van Leeuwen, Fred
Publicado 2020

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms

por Stulemeijer, Iris JE, Pike, Brietta L, Faber, Alex W, Verzijlbergen, Kitty F, van Welsem, Tibor, Frederiks, Floor, Lenstra, Tineke L, Holstege, Frank CP, Gasser, Susan M, van Leeuwen, Fred
Publicado 2011

Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

por Vlaming, Hanneke, Molenaar, Thom M, van Welsem, Tibor, Poramba-Liyanage, Deepani W, Smith, Desiree E, Velds, Arno, Hoekman, Liesbeth, Korthout, Tessy, Hendriks, Sjoerd, Maarten Altelaar, AF, van Leeuwen, Fred
Publicado 2016

A Key Role for Chd1 in Histone H3 Dynamics at the 3′ Ends of Long Genes in Yeast

por Radman-Livaja, Marta, Quan, Tiffani K., Valenzuela, Lourdes, Armstrong, Jennifer A., van Welsem, Tibor, Kim, TaeSoo, Lee, Laura J., Buratowski, Stephen, van Leeuwen, Fred, Rando, Oliver J., Hartzog, Grant A.
Publicado 2012

The histone methyltransferase SETD2 negatively regulates cell size

por Molenaar, Thom M., Malik, Muddassir, Silva, Joana, Liu, Ning Qing, Haarhuis, Judith H. I., Ambrosi, Christina, Kwesi-Maliepaard, Eliza Mari, van Welsem, Tibor, Baubec, Tuncay, Faller, William J., van Leeuwen, Fred
Publicado 2022

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties

por Stulemeijer, Iris J. E., De Vos, Dirk, van Harten, Kirsten, Joshi, Onkar K., Blomberg, Olga, van Welsem, Tibor, Terweij, Marit, Vlaming, Hanneke, de Graaf, Erik L., Altelaar, A. F. Maarten, Bakker, Barbara M., van Leeuwen, Fred
Publicado 2015

Histone methyltransferase DOT1L controls state‐specific identity during B cell differentiation

por Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Kwesi‐Maliepaard, Eliza Mari, Muhaimin, Fitriari Izzatunnisa, Caganova, Marieta, Pardieck, Iris N, van den Brand, Teun, van Welsem, Tibor, de Rink, Iris, Song, Ji‐Ying, de Wit, Elzo, Arens, Ramon, Jacobs, Heinz, van Leeuwen, Fred
Publicado 2021

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

por Vlaming, Hanneke, McLean, Chelsea M, Korthout, Tessy, Alemdehy, Mir Farshid, Hendriks, Sjoerd, Lancini, Cesare, Palit, Sander, Klarenbeek, Sjoerd, Kwesi‐Maliepaard, Eliza Mari, Molenaar, Thom M, Hoekman, Liesbeth, Schmidlin, Thierry T, Altelaar, AF Maarten, van Welsem, Tibor, Dannenberg, Jan‐Hermen, Jacobs, Heinz, van Leeuwen, Fred
Publicado 2019

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8(+) T cells

por Kwesi-Maliepaard, Eliza Mari, Aslam, Muhammad Assad, Alemdehy, Mir Farshid, van den Brand, Teun, McLean, Chelsea, Vlaming, Hanneke, van Welsem, Tibor, Korthout, Tessy, Lancini, Cesare, Hendriks, Sjoerd, Ahrends, Tomasz, van Dinther, Dieke, den Haan, Joke M. M., Borst, Jannie, de Wit, Elzo, van Leeuwen, Fred, Jacobs, Heinz
Publicado 2020

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism

por van Welsem, Tibor, Korthout, Tessy, Ekkebus, Reggy, Morais, Dominique, Molenaar, Thom M, van Harten, Kirsten, Poramba-Liyanage, Deepani W, Sun, Su Ming, Lenstra, Tineke L, Srivas, Rohith, Ideker, Trey, Holstege, Frank C P, van Attikum, Haico, El Oualid, Farid, Ovaa, Huib, Stulemeijer, Iris J E, Vlaming, Hanneke, van Leeuwen, Fred
Publicado 2018