Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity

por Kim, Robbert Q., Geurink, Paul P., Mulder, Monique P. C., Fish, Alexander, Ekkebus, Reggy, El Oualid, Farid, van Dijk, Willem J., van Dalen, Duco, Ovaa, Huib, van Ingen, Hugo, Sixma, Titia K.
Publicado 2019

Development of Diubiquitin‐Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

por Geurink, Paul P., van Tol, Bianca D. M., van Dalen, Duco, Brundel, Paul J. G., Mevissen, Tycho E. T., Pruneda, Jonathan N., Elliott, Paul R., van Tilburg, Gabriëlle B. A., Komander, David, Ovaa, Huib
Publicado 2016

Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody

por van Elsas, Marit J., van der Schoot, Johan M. S., Bartels, Alexander, Steuten, Kas, van Dalen, Duco, Wijfjes, Zacharias, Figdor, Carl G., van Hall, Thorbald, van der Burg, Sjoerd H., Verdoes, Martijn, Scheeren, Ferenc A.
Publicado 2022

Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents

por Hagemans, Iris M., Wierstra, Peter J., Steuten, Kas, Molkenboer-Kuenen, Janneke D. M., van Dalen, Duco, ter Beest, Martin, van der Schoot, Johan M. S., Ilina, Olga, Gotthardt, Martin, Figdor, Carl G., Scheeren, Ferenc A., Heskamp, Sandra, Verdoes, Martijn
Publicado 2022

Correction to: Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents Iris

por Hagemans, Iris M., Wierstra, Peter J., Steuten, Kas, Molkenboer-Kuenen, Janneke D. M., van Dalen, Duco, ter Beest, Martin, van der Schoot, Johan M. S., Ilina, Olga, Gotthardt, Martin, Figdor, Carl G., Scheeren, Ferenc A., Heskamp, Sandra, Verdoes, Martijn
Publicado 2022

Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering

por Le Gall, Camille M., van der Schoot, Johan M. S., Ramos-Tomillero, Iván, Khalily, Melek Parlak, van Dalen, Floris J., Wijfjes, Zacharias, Smeding, Liyan, van Dalen, Duco, Cammarata, Anna, Bonger, Kimberly M., Figdor, Carl G., Scheeren, Ferenc A., Verdoes, Martijn
Publicado 2021

Allosteric control of Ubp6 and the proteasome via a bidirectional switch

por Hung, Ka Ying Sharon, Klumpe, Sven, Eisele, Markus R., Elsasser, Suzanne, Tian, Geng, Sun, Shuangwu, Moroco, Jamie A., Cheng, Tat Cheung, Joshi, Tapan, Seibel, Timo, Van Dalen, Duco, Feng, Xin-Hua, Lu, Ying, Ovaa, Huib, Engen, John R., Lee, Byung-Hoon, Rudack, Till, Sakata, Eri, Finley, Daniel
Publicado 2022

Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

por van der Schoot, Johan M. S., Fennemann, Felix L., Valente, Michael, Dolen, Yusuf, Hagemans, Iris M., Becker, Anouk M. D., Le Gall, Camille M., van Dalen, Duco, Cevirgel, Alper, van Bruggen, Jaco A. C., Engelfriet, Melanie, Caval, Tomislav, Bentlage, Arthur E. H., Fransen, Marieke F., Nederend, Maaike, Leusen, Jeanette H. W., Heck, Albert J. R., Vidarsson, Gestur, Figdor, Carl G., Verdoes, Martijn, Scheeren, Ferenc A.
Publicado 2019