Chemical Tools to Study Protein ADP-Ribosylation

por van der Heden van Noort, Gerbrand J.
Publicado 2020

How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling

por van der Heden van Noort, Gerbrand J., Ovaa, Huib
Publicado 2018

Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor

por Hameed, Dharjath S., Ovaa, Huib, van der Heden van Noort, Gerbrand J., Sapmaz, Aysegul
Publicado 2022

Total Chemical Synthesis of LC3A and LC3B Activity-Based Probes

por Huppelschoten, Yara, Buchardt, Jens, Nielsen, Thomas E., Sapmaz, Aysegul, van der Heden van Noort, Gerbrand J.
Publicado 2023

Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer

por van der Heden van Noort, Gerbrand J., Kooij, Raymond, Elliott, Paul R., Komander, David, Ovaa, Huib
Publicado 2017

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease

por Békés, Miklós, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Ovaa, Huib, Huang, Tony T., Lima, Christopher D.
Publicado 2016

Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases

por Kang, Sangwoo, Kim, Gyuhee, Choi, Minhyeong, Jeong, Minwoo, van der Heden van Noort, Gerbrand J, Roh, Soung-Hun, Shin, Donghyuk
Publicado 2023

In‐Plate Chemical Synthesis of Isopeptide‐Linked SUMOylated Peptide Fluorescence Polarization Reagents for High‐Throughput Screening of SENP Preferences

por Huppelschoten, Yara, Mukhopadhyay, Rishov, Buchardt, Jens, Nielsen, Thomas E., Vertegaal, Alfred C. O., Ovaa, Huib, van der Heden van Noort, Gerbrand J.
Publicado 2022

Profiling DUBs and Ubl-specific proteases with activity-based probes

por Geurink, Paul P., van der Heden van Noort, Gerbrand J., Mulder, Monique P.C., Knaap, Robert C.M., Kikkert, Marjolein, Ovaa, Huib
Publicado 2019

Total Chemical Synthesis of a Functionalized GFP Nanobody

por Huppelschoten, Yara, Elhebieshy, Angela F., Hameed, Dharjath S., Sapmaz, Aysegul, Buchardt, Jens, Nielsen, Thomas E., Ovaa, Huib, van der Heden van Noort, Gerbrand J.
Publicado 2022

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

por Flierman, Dennis, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Geurink, Paul P., Mevissen, Tycho E.T., Hospenthal, Manuela K., Komander, David, Ovaa, Huib
Publicado 2016

Generation of the UFM1 Toolkit for Profiling UFM1‐Specific Proteases and Ligases

por Witting, Katharina F., van der Heden van Noort, Gerbrand J., Kofoed, Christian, Talavera Ormeño, Cami, el Atmioui, Dris, Mulder, Monique P. C., Ovaa, Huib
Publicado 2018

Physicochemical property consensus sequences for functional analysis, design of multivalent antigens and targeted antivirals

por Schein, Catherine H, Bowen, David M, Lewis, Jessica A, Choi, Kyung, Paul, Aniko, van der Heden van Noort, Gerbrand J, Lu, Wenzhe, Filippov, Dmitri V
Publicado 2012

Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

por Shin, Donghyuk, Bhattacharya, Anshu, Cheng, Yi-Lin, Alonso, Marta Campos, Mehdipour, Ahmad Reza, van der Heden van Noort, Gerbrand J, Ovaa, Huib, Hummer, Gerhard, Dikic, Ivan
Publicado 2020

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System

por Janssen, Guido V., Zhang, Susan, Merkx, Remco, Schiesswohl, Christa, Chatterjee, Champak, Darwin, K. Heran, Geurink, Paul P., van der Heden van Noort, Gerbrand J., Ovaa, Huib
Publicado 2021

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection

por Kim, Robbert Q., Misra, Mohit, Gonzalez, Alexis, Tomašković, Ines, Shin, Donghyuk, Schindelin, Hermann, Filippov, Dmitri V., Ovaa, Huib, Đikić, Ivan, van der Heden van Noort, Gerbrand J.
Publicado 2020

Nedd8 hydrolysis by UCH proteases in Plasmodium parasites

por Karpiyevich, Maryia, Adjalley, Sophie, Mol, Marco, Ascher, David B., Mason, Bethany, van der Heden van Noort, Gerbrand J., Laman, Heike, Ovaa, Huib, Lee, Marcus C. S., Artavanis-Tsakonas, Katerina
Publicado 2019

Synthesis of Stable NAD(+) Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC

por Madern, Jerre M., Kim, Robbert Q., Misra, Mohit, Dikic, Ivan, Zhang, Yong, Ovaa, Huib, Codée, Jeroen D. C., Filippov, Dmitri V., van der Heden van Noort, Gerbrand J.
Publicado 2020

Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins

por Voorneveld, Jim, Kloet, Max S., Wijngaarden, Sven, Kim, Robbert Q., Moutsiopoulou, Angeliki, Verdegaal, Marnix, Misra, Mohit, Đikić, Ivan, van der Marel, Gijsbert A., Overkleeft, Herman S., Filippov, Dmitri V., van der Heden van Noort, Gerbrand J.
Publicado 2022

Modification of picornavirus genomic RNA using ‘click’ chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA...

por Langereis, Martijn A., Feng, Qian, Nelissen, Frank H. T., Virgen-Slane, Richard, van der Heden van Noort, Gerbrand J., Maciejewski, Sonia, Filippov, Dmitri V., Semler, Bert L., van Delft, Floris L., van Kuppeveld, Frank J.M.
Publicado 2014